Early clinical experience with subcutaneous GR43175 in acute migraine: an overview
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Early clinical experience with subcutaneous GR43175 in acute migraine : an overview. / Tfelt-Hansen, P; Brand, J; Dano, P; Doenicke, A; Findley, L J; Iversen, Helle Klingenberg; Melchart, D; Sahlender, H M.
In: Cephalalgia : an international journal of headache, Vol. 9 Suppl 9, 1989, p. 73-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Early clinical experience with subcutaneous GR43175 in acute migraine
T2 - an overview
AU - Tfelt-Hansen, P
AU - Brand, J
AU - Dano, P
AU - Doenicke, A
AU - Findley, L J
AU - Iversen, Helle Klingenberg
AU - Melchart, D
AU - Sahlender, H M
PY - 1989
Y1 - 1989
N2 - In six European clinics 111 migraine patients were treated in a series of open dose-ranging studies with subcutaneous injections of 1 to 4 mg GR43175, a novel 5-HT 1-like receptor agonist. Response rates after 20-30 min were dose related and rose from 33% with 1 mg to 96% with 4 mg GR43175. Side effects were minor and transient. These promising results warrant confirmation in placebo-controlled double-blind trials. Migraine, treatment, 5-HT agonist, open studies.
AB - In six European clinics 111 migraine patients were treated in a series of open dose-ranging studies with subcutaneous injections of 1 to 4 mg GR43175, a novel 5-HT 1-like receptor agonist. Response rates after 20-30 min were dose related and rose from 33% with 1 mg to 96% with 4 mg GR43175. Side effects were minor and transient. These promising results warrant confirmation in placebo-controlled double-blind trials. Migraine, treatment, 5-HT agonist, open studies.
KW - Adolescent
KW - Adult
KW - Aged
KW - Dose-Response Relationship, Drug
KW - Female
KW - Humans
KW - Indoles
KW - Injections, Subcutaneous
KW - Male
KW - Middle Aged
KW - Migraine Disorders
KW - Sulfonamides
KW - Sumatriptan
M3 - Journal article
C2 - 2544287
VL - 9 Suppl 9
SP - 73
EP - 77
JO - Cephalalgia
JF - Cephalalgia
SN - 0800-1952
ER -
ID: 128984851