Duration of Psoriatic Skin Disease as Risk Factor for Subsequent Onset of Psoriatic Arthritis
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Duration of Psoriatic Skin Disease as Risk Factor for Subsequent Onset of Psoriatic Arthritis. / Egeberg, Alexander; Skov, Lone; Zachariae, Claus; Gislason, Gunnar H; Thyssen, Jacob P; Mallbris, Lotus.
In: Acta Dermato-Venereologica, Vol. 98, No. 6, 2018, p. 546-550.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Duration of Psoriatic Skin Disease as Risk Factor for Subsequent Onset of Psoriatic Arthritis
AU - Egeberg, Alexander
AU - Skov, Lone
AU - Zachariae, Claus
AU - Gislason, Gunnar H
AU - Thyssen, Jacob P
AU - Mallbris, Lotus
PY - 2018
Y1 - 2018
N2 - It is unclear whether psoriasis is a progressive disease that requires early aggressive intervention. This population-based study identified patients with psoriasis and psoriatic arthritis (PsA). Survival analysis and Kaplan-Meier life table techniques were used. The study comprised 10,011 psoriasis patients (severe n = 4,618), and 1,269 patients also had PsA. Incidence of PsA increased with duration of cutaneous symptoms (p = 0.0001). Psoriasis diagnosed before age 20 or 30 years, respectively, suggested a lower risk of PsA than psoriasis diagnosed after age 50 years, yet age at first cutaneous symptoms did not predict development of PsA. No clear association with disease severity was found. PsA incidence appeared stable with longer duration of psoriasis, but further data are needed to firmly establish the relationship with age of psoriasis onset.
AB - It is unclear whether psoriasis is a progressive disease that requires early aggressive intervention. This population-based study identified patients with psoriasis and psoriatic arthritis (PsA). Survival analysis and Kaplan-Meier life table techniques were used. The study comprised 10,011 psoriasis patients (severe n = 4,618), and 1,269 patients also had PsA. Incidence of PsA increased with duration of cutaneous symptoms (p = 0.0001). Psoriasis diagnosed before age 20 or 30 years, respectively, suggested a lower risk of PsA than psoriasis diagnosed after age 50 years, yet age at first cutaneous symptoms did not predict development of PsA. No clear association with disease severity was found. PsA incidence appeared stable with longer duration of psoriasis, but further data are needed to firmly establish the relationship with age of psoriasis onset.
KW - Adult
KW - Age of Onset
KW - Aged
KW - Arthritis, Psoriatic/diagnosis
KW - Denmark/epidemiology
KW - Female
KW - Humans
KW - Incidence
KW - Kaplan-Meier Estimate
KW - Logistic Models
KW - Male
KW - Middle Aged
KW - Odds Ratio
KW - Prevalence
KW - Psoriasis/diagnosis
KW - Registries
KW - Risk Factors
KW - Time Factors
KW - Young Adult
U2 - 10.2340/00015555-2912
DO - 10.2340/00015555-2912
M3 - Journal article
C2 - 29487945
VL - 98
SP - 546
EP - 550
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 6
ER -
ID: 213915403