Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression: A randomised, double-blind pilot study
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Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression : A randomised, double-blind pilot study. / Søndergaard, M. P.; Jarden, J. O.; Martiny, K.; Andersen, G.; Bech, P.
In: Psychotherapy and Psychosomatics, Vol. 75, No. 4, 01.06.2006, p. 244-248.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression
T2 - A randomised, double-blind pilot study
AU - Søndergaard, M. P.
AU - Jarden, J. O.
AU - Martiny, K.
AU - Andersen, G.
AU - Bech, P.
PY - 2006/6/1
Y1 - 2006/6/1
N2 - Background: Post-stroke depression affects the outcome of stroke rehabilitation and is observed in approximately 30% of all stroke patients. We investigated whetherthe addition of light treatment to medical antidepressants influences the course of depression as measured by the Hamilton Depression Scale. Methods: The effect of a combination of light therapy and citalopram in stroke victims receiving citalopram was examined by use of two different doses of light therapy under double-blind conditions. Altogether, 63 patients were included in the study. The mean age was 74.9 years. Results: After 4 weeks of therapy, the 6-item subscale of the Hamilton Depression Scale showed a statistically significantly larger improvement in patients receiving high-intensity light treatment compared to those treated with medium-intensity light (p < 0.05). Conclusion: This pilot study demonstrates a dose response effect of light used as an adjunct therapy to antidepressants in post-stroke patients with major depression.
AB - Background: Post-stroke depression affects the outcome of stroke rehabilitation and is observed in approximately 30% of all stroke patients. We investigated whetherthe addition of light treatment to medical antidepressants influences the course of depression as measured by the Hamilton Depression Scale. Methods: The effect of a combination of light therapy and citalopram in stroke victims receiving citalopram was examined by use of two different doses of light therapy under double-blind conditions. Altogether, 63 patients were included in the study. The mean age was 74.9 years. Results: After 4 weeks of therapy, the 6-item subscale of the Hamilton Depression Scale showed a statistically significantly larger improvement in patients receiving high-intensity light treatment compared to those treated with medium-intensity light (p < 0.05). Conclusion: This pilot study demonstrates a dose response effect of light used as an adjunct therapy to antidepressants in post-stroke patients with major depression.
KW - Citalopram
KW - Light therapy
KW - Post-stroke depression
U2 - 10.1159/000092895
DO - 10.1159/000092895
M3 - Journal article
C2 - 16785774
AN - SCOPUS:33745319041
VL - 75
SP - 244
EP - 248
JO - Psychotherapy and Psychosomatics
JF - Psychotherapy and Psychosomatics
SN - 0033-3190
IS - 4
ER -
ID: 209243383