Do changes in lymph node status distribution explain trends in survival of breast cancer patients in Denmark?
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Do changes in lymph node status distribution explain trends in survival of breast cancer patients in Denmark? / Rostgaard, Klaus; Vaeth, Michael; Rootzén, Helle; Mouridsen, Henning; Olesen, Knud P; Lynge, Elsebeth.
In: European Journal of Cancer Prevention, Vol. 15, No. 5, 2006, p. 398-404.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Do changes in lymph node status distribution explain trends in survival of breast cancer patients in Denmark?
AU - Rostgaard, Klaus
AU - Vaeth, Michael
AU - Rootzén, Helle
AU - Mouridsen, Henning
AU - Olesen, Knud P
AU - Lynge, Elsebeth
N1 - Keywords: Aged; Breast Neoplasms; Denmark; Female; Humans; Incidence; Lymph Nodes; Middle Aged; Survival Analysis; Survival Rate
PY - 2006
Y1 - 2006
N2 - We studied the impact on survival of changes in breast cancer patients' distribution by lymph node status at the time of diagnosis. Our study included breast cancer patients diagnosed from 1978 to 1994 in Denmark, where the treatment schemes for breast cancer patients were fairly stable, and where mammography screening was limited. We measured lymph node status by the proportion of positive lymph nodes of all excised lymph nodes, as assessed by a pathologist. This measure was available for two-thirds of the breast cancer patients. The outcome was 5-year relative survival. Changes in lymph node status distribution explained half of the improvement in 5-year relative survival, and seem to be the single most important cause behind the improved survival of breast cancer patients in Denmark.
AB - We studied the impact on survival of changes in breast cancer patients' distribution by lymph node status at the time of diagnosis. Our study included breast cancer patients diagnosed from 1978 to 1994 in Denmark, where the treatment schemes for breast cancer patients were fairly stable, and where mammography screening was limited. We measured lymph node status by the proportion of positive lymph nodes of all excised lymph nodes, as assessed by a pathologist. This measure was available for two-thirds of the breast cancer patients. The outcome was 5-year relative survival. Changes in lymph node status distribution explained half of the improvement in 5-year relative survival, and seem to be the single most important cause behind the improved survival of breast cancer patients in Denmark.
M3 - Journal article
C2 - 16912568
VL - 15
SP - 398
EP - 404
JO - European Journal of Cancer Prevention
JF - European Journal of Cancer Prevention
SN - 0959-8278
IS - 5
ER -
ID: 8592338