Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

Research output: Contribution to journalConference abstract in journalResearch

Standard

Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity. / Stella, Stefano; Mesa, Pablo; Thomsen, Johannes; Paul, Bijoya; Alcon, Pablo; Jensen, Simon B.; Moses, Matias E.; Montoya, Guillermo; Hatzakis, Nikos S.

In: Biophysical Journal, Vol. 118, No. 3, 07.02.2020, p. 223A-224A.

Research output: Contribution to journalConference abstract in journalResearch

Harvard

Stella, S, Mesa, P, Thomsen, J, Paul, B, Alcon, P, Jensen, SB, Moses, ME, Montoya, G & Hatzakis, NS 2020, 'Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity', Biophysical Journal, vol. 118, no. 3, pp. 223A-224A. https://doi.org/10.1016/j.bpj.2019.11.1324

APA

Stella, S., Mesa, P., Thomsen, J., Paul, B., Alcon, P., Jensen, S. B., Moses, M. E., Montoya, G., & Hatzakis, N. S. (2020). Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity. Biophysical Journal, 118(3), 223A-224A. https://doi.org/10.1016/j.bpj.2019.11.1324

Vancouver

Stella S, Mesa P, Thomsen J, Paul B, Alcon P, Jensen SB et al. Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity. Biophysical Journal. 2020 Feb 7;118(3):223A-224A. https://doi.org/10.1016/j.bpj.2019.11.1324

Author

Stella, Stefano ; Mesa, Pablo ; Thomsen, Johannes ; Paul, Bijoya ; Alcon, Pablo ; Jensen, Simon B. ; Moses, Matias E. ; Montoya, Guillermo ; Hatzakis, Nikos S. / Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity. In: Biophysical Journal. 2020 ; Vol. 118, No. 3. pp. 223A-224A.

Bibtex

@article{dcb288d9dac448c6ac4b1e2c26400fdf,
title = "Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity",
author = "Stefano Stella and Pablo Mesa and Johannes Thomsen and Bijoya Paul and Pablo Alcon and Jensen, {Simon B.} and Moses, {Matias E.} and Guillermo Montoya and Hatzakis, {Nikos S.}",
year = "2020",
month = feb,
day = "7",
doi = "10.1016/j.bpj.2019.11.1324",
language = "English",
volume = "118",
pages = "223A--224A",
journal = "Biophysical Society. Annual Meeting. Abstracts",
issn = "0523-6800",
publisher = "Biophysical Society",
number = "3",

}

RIS

TY - ABST

T1 - Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

AU - Stella, Stefano

AU - Mesa, Pablo

AU - Thomsen, Johannes

AU - Paul, Bijoya

AU - Alcon, Pablo

AU - Jensen, Simon B.

AU - Moses, Matias E.

AU - Montoya, Guillermo

AU - Hatzakis, Nikos S.

PY - 2020/2/7

Y1 - 2020/2/7

U2 - 10.1016/j.bpj.2019.11.1324

DO - 10.1016/j.bpj.2019.11.1324

M3 - Conference abstract in journal

VL - 118

SP - 223A-224A

JO - Biophysical Society. Annual Meeting. Abstracts

JF - Biophysical Society. Annual Meeting. Abstracts

SN - 0523-6800

IS - 3

ER -

ID: 245369521