Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers: the Eurodiale study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers : the Eurodiale study. / Siersma, Volkert; Thorsen, Hanne; Holstein, Per E.; Kars, Marleen; Apelqvist, Jan; Jude, Edward B.; Piaggesi, Alberto; Bakker, Karel; Edmonds, Michael; Jirkovská, Alexandra; Mauricio, Didac; Reike, Heinrich; Spraul, Maximilian; Uccioli, Luigi; Urbancic, Vilma; van Acker, Kristien; van Baal, Jeff; Schaper, Nicolaas C.

In: Journal of Diabetes and its Complications, Vol. 31, No. 7, 07.2017, p. 1145-1151.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Siersma, V, Thorsen, H, Holstein, PE, Kars, M, Apelqvist, J, Jude, EB, Piaggesi, A, Bakker, K, Edmonds, M, Jirkovská, A, Mauricio, D, Reike, H, Spraul, M, Uccioli, L, Urbancic, V, van Acker, K, van Baal, J & Schaper, NC 2017, 'Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers: the Eurodiale study', Journal of Diabetes and its Complications, vol. 31, no. 7, pp. 1145-1151. https://doi.org/10.1016/j.jdiacomp.2017.04.008

APA

Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., Piaggesi, A., Bakker, K., Edmonds, M., Jirkovská, A., Mauricio, D., Reike, H., Spraul, M., Uccioli, L., Urbancic, V., van Acker, K., van Baal, J., & Schaper, N. C. (2017). Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers: the Eurodiale study. Journal of Diabetes and its Complications, 31(7), 1145-1151. https://doi.org/10.1016/j.jdiacomp.2017.04.008

Vancouver

Siersma V, Thorsen H, Holstein PE, Kars M, Apelqvist J, Jude EB et al. Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers: the Eurodiale study. Journal of Diabetes and its Complications. 2017 Jul;31(7):1145-1151. https://doi.org/10.1016/j.jdiacomp.2017.04.008

Author

Siersma, Volkert ; Thorsen, Hanne ; Holstein, Per E. ; Kars, Marleen ; Apelqvist, Jan ; Jude, Edward B. ; Piaggesi, Alberto ; Bakker, Karel ; Edmonds, Michael ; Jirkovská, Alexandra ; Mauricio, Didac ; Reike, Heinrich ; Spraul, Maximilian ; Uccioli, Luigi ; Urbancic, Vilma ; van Acker, Kristien ; van Baal, Jeff ; Schaper, Nicolaas C. / Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers : the Eurodiale study. In: Journal of Diabetes and its Complications. 2017 ; Vol. 31, No. 7. pp. 1145-1151.

Bibtex

@article{071bb0d985a045a28cd2b33ee78937f9,
title = "Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers: the Eurodiale study",
abstract = "Aims: Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. Methods: 1088 patients presenting for DFU treatment at the centers participating in the Eurodiale study were followed prospectively up to one year. HRQoL was measured both at presentation and after healing or at end of follow up, using EQ-5D: a standardized instrument consisting of five domains and a summary index. The influence of diabetic comorbidity on the course of HRQoL was evaluated for each of the EQ-5D outcomes in multi-level linear regression analyses, adjusting for baseline characteristics. Results: HRQoL improved in all EQ-5D outcomes over the course of treatment for those DFUs that healed. The few significant differences in the development of HRQoL between patients with and without comorbidity showed a more beneficial development for patients with comorbidity in DFUs that did not heal or healed slowly. Conclusions: Comorbidity does not hamper improvement of HRQoL in DFU treatment. On the contrary, HRQoL improved sometimes more in patients with certain comorbidity with hard-to-heal ulcers.",
keywords = "Comorbidity, Diabetes mellitus, Diabetic foot ulcer, Health-related quality of life, Longitudinal study",
author = "Volkert Siersma and Hanne Thorsen and Holstein, {Per E.} and Marleen Kars and Jan Apelqvist and Jude, {Edward B.} and Alberto Piaggesi and Karel Bakker and Michael Edmonds and Alexandra Jirkovsk{\'a} and Didac Mauricio and Heinrich Reike and Maximilian Spraul and Luigi Uccioli and Vilma Urbancic and {van Acker}, Kristien and {van Baal}, Jeff and Schaper, {Nicolaas C.}",
year = "2017",
month = jul,
doi = "10.1016/j.jdiacomp.2017.04.008",
language = "English",
volume = "31",
pages = "1145--1151",
journal = "Journal of Diabetes and its Complications",
issn = "1056-8727",
publisher = "Elsevier",
number = "7",

}

RIS

TY - JOUR

T1 - Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers

T2 - the Eurodiale study

AU - Siersma, Volkert

AU - Thorsen, Hanne

AU - Holstein, Per E.

AU - Kars, Marleen

AU - Apelqvist, Jan

AU - Jude, Edward B.

AU - Piaggesi, Alberto

AU - Bakker, Karel

AU - Edmonds, Michael

AU - Jirkovská, Alexandra

AU - Mauricio, Didac

AU - Reike, Heinrich

AU - Spraul, Maximilian

AU - Uccioli, Luigi

AU - Urbancic, Vilma

AU - van Acker, Kristien

AU - van Baal, Jeff

AU - Schaper, Nicolaas C.

PY - 2017/7

Y1 - 2017/7

N2 - Aims: Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. Methods: 1088 patients presenting for DFU treatment at the centers participating in the Eurodiale study were followed prospectively up to one year. HRQoL was measured both at presentation and after healing or at end of follow up, using EQ-5D: a standardized instrument consisting of five domains and a summary index. The influence of diabetic comorbidity on the course of HRQoL was evaluated for each of the EQ-5D outcomes in multi-level linear regression analyses, adjusting for baseline characteristics. Results: HRQoL improved in all EQ-5D outcomes over the course of treatment for those DFUs that healed. The few significant differences in the development of HRQoL between patients with and without comorbidity showed a more beneficial development for patients with comorbidity in DFUs that did not heal or healed slowly. Conclusions: Comorbidity does not hamper improvement of HRQoL in DFU treatment. On the contrary, HRQoL improved sometimes more in patients with certain comorbidity with hard-to-heal ulcers.

AB - Aims: Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. Methods: 1088 patients presenting for DFU treatment at the centers participating in the Eurodiale study were followed prospectively up to one year. HRQoL was measured both at presentation and after healing or at end of follow up, using EQ-5D: a standardized instrument consisting of five domains and a summary index. The influence of diabetic comorbidity on the course of HRQoL was evaluated for each of the EQ-5D outcomes in multi-level linear regression analyses, adjusting for baseline characteristics. Results: HRQoL improved in all EQ-5D outcomes over the course of treatment for those DFUs that healed. The few significant differences in the development of HRQoL between patients with and without comorbidity showed a more beneficial development for patients with comorbidity in DFUs that did not heal or healed slowly. Conclusions: Comorbidity does not hamper improvement of HRQoL in DFU treatment. On the contrary, HRQoL improved sometimes more in patients with certain comorbidity with hard-to-heal ulcers.

KW - Comorbidity

KW - Diabetes mellitus

KW - Diabetic foot ulcer

KW - Health-related quality of life

KW - Longitudinal study

U2 - 10.1016/j.jdiacomp.2017.04.008

DO - 10.1016/j.jdiacomp.2017.04.008

M3 - Journal article

C2 - 28457703

AN - SCOPUS:85018320443

VL - 31

SP - 1145

EP - 1151

JO - Journal of Diabetes and its Complications

JF - Journal of Diabetes and its Complications

SN - 1056-8727

IS - 7

ER -

ID: 179047724