Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit. / Rubinstein, E; Gjørup, I; Schulze, S; Jonsson, T; Højgaard, L.

In: European Journal of Surgery Supplement, Vol. 158, No. 6-7, 01.06.1992, p. 361-4.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Rubinstein, E, Gjørup, I, Schulze, S, Jonsson, T & Højgaard, L 1992, 'Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit', European Journal of Surgery Supplement, vol. 158, no. 6-7, pp. 361-4.

APA

Rubinstein, E., Gjørup, I., Schulze, S., Jonsson, T., & Højgaard, L. (1992). Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit. European Journal of Surgery Supplement, 158(6-7), 361-4.

Vancouver

Rubinstein E, Gjørup I, Schulze S, Jonsson T, Højgaard L. Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit. European Journal of Surgery Supplement. 1992 Jun 1;158(6-7):361-4.

Author

Rubinstein, E ; Gjørup, I ; Schulze, S ; Jonsson, T ; Højgaard, L. / Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit. In: European Journal of Surgery Supplement. 1992 ; Vol. 158, No. 6-7. pp. 361-4.

Bibtex

@article{d992c12c05664986a2a56562df08c493,
title = "Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit",
abstract = "OBJECTIVE: To assess measurement of gastric electrical potential difference, pH of gastric mucosa, and endoscopic findings in patients in intensive care units who are at risk of developing stress ulcers.DESIGN: Open comparison with age- and sex-matched control subjects.SETTING: Herlev Hospital, Denmark.SUBJECTS: Sixteen consecutive patients with no history of gastrointestinal haemorrhage, coagulopathy, or ulcer disease who had been admitted to the intensive care unit, and 16 age- and sex-matched outpatients with normal endoscopic findings.INTERVENTIONS: Upper gastrointestinal endoscopy, during which any lesions that were found were scored according to severity, the gastric potential difference, and the pH of gastric juice were measured.OUTCOME MEASURES: Correlation between the incidence of stress ulceration found at endoscopy, gastric potential difference, and gastric pH.RESULTS: Gastric potential difference was significantly reduced and gastric pH significantly increased in the patients in the intensive care unit (p less than 0.05 in both cases), all of whom had stress ulcers in more than one gastric segment. Nine of the patients had gastric pH readings of greater than 4.CONCLUSION: Gastric electrical potential difference may be useful measurement for the assessment of stress ulceration in patients in intensive care units.",
keywords = "Adult, Aged, Case-Control Studies, Female, Gastric Acid, Gastric Acidity Determination, Gastroscopy, Humans, Hydrogen-Ion Concentration, Intensive Care Units, Male, Membrane Potentials, Middle Aged, Stomach Ulcer, Stress, Physiological, Journal Article",
author = "E Rubinstein and I Gj{\o}rup and S Schulze and T Jonsson and L H{\o}jgaard",
year = "1992",
month = jun,
day = "1",
language = "English",
volume = "158",
pages = "361--4",
journal = "European Journal of Surgery, Acta Chirurgica, Supplement",
issn = "1102-416X",
publisher = "Universitetsforlaget AS",
number = "6-7",

}

RIS

TY - JOUR

T1 - Development of stress ulcers assessed by gastric electrical potential difference, pH of gastric juice, and endoscopy in patients in the intensive care unit

AU - Rubinstein, E

AU - Gjørup, I

AU - Schulze, S

AU - Jonsson, T

AU - Højgaard, L

PY - 1992/6/1

Y1 - 1992/6/1

N2 - OBJECTIVE: To assess measurement of gastric electrical potential difference, pH of gastric mucosa, and endoscopic findings in patients in intensive care units who are at risk of developing stress ulcers.DESIGN: Open comparison with age- and sex-matched control subjects.SETTING: Herlev Hospital, Denmark.SUBJECTS: Sixteen consecutive patients with no history of gastrointestinal haemorrhage, coagulopathy, or ulcer disease who had been admitted to the intensive care unit, and 16 age- and sex-matched outpatients with normal endoscopic findings.INTERVENTIONS: Upper gastrointestinal endoscopy, during which any lesions that were found were scored according to severity, the gastric potential difference, and the pH of gastric juice were measured.OUTCOME MEASURES: Correlation between the incidence of stress ulceration found at endoscopy, gastric potential difference, and gastric pH.RESULTS: Gastric potential difference was significantly reduced and gastric pH significantly increased in the patients in the intensive care unit (p less than 0.05 in both cases), all of whom had stress ulcers in more than one gastric segment. Nine of the patients had gastric pH readings of greater than 4.CONCLUSION: Gastric electrical potential difference may be useful measurement for the assessment of stress ulceration in patients in intensive care units.

AB - OBJECTIVE: To assess measurement of gastric electrical potential difference, pH of gastric mucosa, and endoscopic findings in patients in intensive care units who are at risk of developing stress ulcers.DESIGN: Open comparison with age- and sex-matched control subjects.SETTING: Herlev Hospital, Denmark.SUBJECTS: Sixteen consecutive patients with no history of gastrointestinal haemorrhage, coagulopathy, or ulcer disease who had been admitted to the intensive care unit, and 16 age- and sex-matched outpatients with normal endoscopic findings.INTERVENTIONS: Upper gastrointestinal endoscopy, during which any lesions that were found were scored according to severity, the gastric potential difference, and the pH of gastric juice were measured.OUTCOME MEASURES: Correlation between the incidence of stress ulceration found at endoscopy, gastric potential difference, and gastric pH.RESULTS: Gastric potential difference was significantly reduced and gastric pH significantly increased in the patients in the intensive care unit (p less than 0.05 in both cases), all of whom had stress ulcers in more than one gastric segment. Nine of the patients had gastric pH readings of greater than 4.CONCLUSION: Gastric electrical potential difference may be useful measurement for the assessment of stress ulceration in patients in intensive care units.

KW - Adult

KW - Aged

KW - Case-Control Studies

KW - Female

KW - Gastric Acid

KW - Gastric Acidity Determination

KW - Gastroscopy

KW - Humans

KW - Hydrogen-Ion Concentration

KW - Intensive Care Units

KW - Male

KW - Membrane Potentials

KW - Middle Aged

KW - Stomach Ulcer

KW - Stress, Physiological

KW - Journal Article

M3 - Journal article

C2 - 1356469

VL - 158

SP - 361

EP - 364

JO - European Journal of Surgery, Acta Chirurgica, Supplement

JF - European Journal of Surgery, Acta Chirurgica, Supplement

SN - 1102-416X

IS - 6-7

ER -

ID: 165884926