Delabeling of Penicillin Allergy: Room for Improvement
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Delabeling of Penicillin Allergy : Room for Improvement. / Fransson, Sara; Damving, Christina Monnerup; Boel, Jonas Bredtoft; Arpi, Magnus; Skinhøj, Ida Gjørup; Jarløv, Jens Otto; Mosbech, Holger F; Poulsen, Lars K; Garvey, Lene H.
In: International Archives of Allergy and Immunology, Vol. 184, No. 9, 2023, p. 870–874.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Delabeling of Penicillin Allergy
T2 - Room for Improvement
AU - Fransson, Sara
AU - Damving, Christina Monnerup
AU - Boel, Jonas Bredtoft
AU - Arpi, Magnus
AU - Skinhøj, Ida Gjørup
AU - Jarløv, Jens Otto
AU - Mosbech, Holger F
AU - Poulsen, Lars K
AU - Garvey, Lene H
N1 - © 2023 S. Karger AG, Basel.
PY - 2023
Y1 - 2023
N2 - BACKGROUND: Penicillin allergy labels have been shown to be associated with suboptimal treatment, negative health outcomes, and increased antibiotic resistance. Many inpatients claim to have penicillin allergy, but studies show that allergy can be disproved and the label removed in up to 90% of cases.OBJECTIVES: The purpose of the study was to investigate the proportion of patients with a penicillin allergy label in a Danish hospital and to classify patients according to the risk of having penicillin allergy in "no risk," low, and high risk.METHODS: For 22 days, inpatients with penicillin allergy labels were interviewed, had their dispensed penicillin prescriptions examined, and were subsequently categorized into risk groups based on the risk evaluation criteria in national guidelines.RESULTS: In total, 260 patients had a penicillin allergy label (10% of the inpatients). Out of 151 included patients, 25 were "no risk" patients (17%), who could potentially have their penicillin allergy label removed without testing. 42 were low-risk patients (28%). 10 "no risk" patients and 20 low-risk patients had been prescribed and dispensed one or more penicillins despite an allergy label.CONCLUSION: Ten percent of inpatients have a penicillin allergy label in a Danish hospital. 17% of these could potentially have their penicillin allergy label removed without allergy testing.
AB - BACKGROUND: Penicillin allergy labels have been shown to be associated with suboptimal treatment, negative health outcomes, and increased antibiotic resistance. Many inpatients claim to have penicillin allergy, but studies show that allergy can be disproved and the label removed in up to 90% of cases.OBJECTIVES: The purpose of the study was to investigate the proportion of patients with a penicillin allergy label in a Danish hospital and to classify patients according to the risk of having penicillin allergy in "no risk," low, and high risk.METHODS: For 22 days, inpatients with penicillin allergy labels were interviewed, had their dispensed penicillin prescriptions examined, and were subsequently categorized into risk groups based on the risk evaluation criteria in national guidelines.RESULTS: In total, 260 patients had a penicillin allergy label (10% of the inpatients). Out of 151 included patients, 25 were "no risk" patients (17%), who could potentially have their penicillin allergy label removed without testing. 42 were low-risk patients (28%). 10 "no risk" patients and 20 low-risk patients had been prescribed and dispensed one or more penicillins despite an allergy label.CONCLUSION: Ten percent of inpatients have a penicillin allergy label in a Danish hospital. 17% of these could potentially have their penicillin allergy label removed without allergy testing.
U2 - 10.1159/000530770
DO - 10.1159/000530770
M3 - Journal article
C2 - 37321191
VL - 184
SP - 870
EP - 874
JO - International Archives of Allergy and Immunology
JF - International Archives of Allergy and Immunology
SN - 1018-2438
IS - 9
ER -
ID: 359338709