Cost-effectiveness analysis of introducing RDTs for malaria diagnosis as compared to microscopy and presumptive diagnosis in central and peripheral public health facilities in Ghana
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Cost-effectiveness analysis of introducing RDTs for malaria diagnosis as compared to microscopy and presumptive diagnosis in central and peripheral public health facilities in Ghana. / Ansah, Evelyn K; Epokor, Michael; Whitty, Christopher J M; Yeung, Shunmay; Hansen, Kristian Schultz.
In: American Journal of Tropical Medicine and Hygiene, Vol. 89, No. 4, 10.2013, p. 724-36.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Cost-effectiveness analysis of introducing RDTs for malaria diagnosis as compared to microscopy and presumptive diagnosis in central and peripheral public health facilities in Ghana
AU - Ansah, Evelyn K
AU - Epokor, Michael
AU - Whitty, Christopher J M
AU - Yeung, Shunmay
AU - Hansen, Kristian Schultz
PY - 2013/10
Y1 - 2013/10
N2 - Cost-effectiveness information on where malaria rapid diagnostic tests (RDTs) should be introduced is limited. We developed incremental cost-effectiveness analyses with data from rural health facilities in Ghana with and without microscopy. In the latter, where diagnosis had been presumptive, the introduction of RDTs increased the proportion of patients who were correctly treated in relation to treatment with antimalarials, from 42% to 65% at an incremental societal cost of Ghana cedis (GHS)12.2 (US$8.3) per additional correctly treated patients. In the "microscopy setting" there was no advantage to replacing microscopy by RDT as the cost and proportion of correctly treated patients were similar. Results were sensitive to a decrease in the cost of RDTs, which cost GHS1.72 (US$1.17) per test at the time of the study and to improvements in adherence to negative tests that was just above 50% for both RDTs and microscopy.
AB - Cost-effectiveness information on where malaria rapid diagnostic tests (RDTs) should be introduced is limited. We developed incremental cost-effectiveness analyses with data from rural health facilities in Ghana with and without microscopy. In the latter, where diagnosis had been presumptive, the introduction of RDTs increased the proportion of patients who were correctly treated in relation to treatment with antimalarials, from 42% to 65% at an incremental societal cost of Ghana cedis (GHS)12.2 (US$8.3) per additional correctly treated patients. In the "microscopy setting" there was no advantage to replacing microscopy by RDT as the cost and proportion of correctly treated patients were similar. Results were sensitive to a decrease in the cost of RDTs, which cost GHS1.72 (US$1.17) per test at the time of the study and to improvements in adherence to negative tests that was just above 50% for both RDTs and microscopy.
KW - Antimalarials
KW - Cost-Benefit Analysis
KW - Ghana
KW - Health Care Costs
KW - Humans
KW - Malaria
KW - Public Health
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.4269/ajtmh.13-0033
DO - 10.4269/ajtmh.13-0033
M3 - Journal article
C2 - 23980131
VL - 89
SP - 724
EP - 736
JO - Journal. National Malaria Society
JF - Journal. National Malaria Society
SN - 0002-9637
IS - 4
ER -
ID: 168569706