TY - JOUR

T1 - Clinical characteristics of pediatric hidradenitis suppurativa

T2 - a cross-sectional multicenter study of 140 patients

AU - Riis, Peter Theut

AU - Saunte, Ditte Marie

AU - Sigsgaard, Viktoria

AU - Villani, Axel Patrice

AU - Guillem, Philippe

AU - Pascual, José C.

AU - Kappe, Naomi N.

AU - Vanlaerhoven, Annika M.J.D.

AU - van der Zee, Hessel H.

AU - Prens, Errol P.

AU - El-Domyati, Moetaz

AU - Abdel-Wahab, Hossam

AU - Moftah, Nayera

AU - Abdelghani, Rania

AU - Agut-Busquet, Eugenia

AU - Romaní, Jorge

AU - Hlela, Carol

AU - van den Worm, Lerinza

AU - Bettoli, Vincenzo

AU - Calamo, Giada

AU - Gürer, Mehmet Ali

AU - Beksaç, Burcu

AU - Matusiak, Lukasz

AU - Glowaczewska, Amelia

AU - Szepietowski, Jacek C.

AU - Emtestam, Lennart

AU - Lapins, Jan

AU - Kottb, Hassan Riad

AU - Fatani, Mohammad

AU - Weibel, Lisa

AU - Theiler, Martin

AU - Delage-Toriel, Maïa

AU - Lam, Thi Thanh Hong

AU - Nassif, Aude

AU - Becherel, Pierre Andre

AU - Dolenc-Voljc, Mateja

AU - Doss, Nejib

AU - Bouazzi, Dorra

AU - Benhadou, Farida

AU - del Marmol, Veronique

AU - Jemec, Gregor B.E.

PY - 2020/12/1

Y1 - 2020/12/1

N2 - Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.

AB - Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.

KW - Acne inversa

KW - Children

KW - Hidradenitis suppurativa

KW - Pediatric

U2 - 10.1007/s00403-020-02053-6

DO - 10.1007/s00403-020-02053-6

M3 - Journal article

C2 - 32166376

AN - SCOPUS:85081751716

VL - 312

SP - 715

EP - 724

JO - Archiv für Dermatologische Forschung

JF - Archiv für Dermatologische Forschung

SN - 0340-3696

IS - 10

ER -