Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

Research output: Contribution to journal › Review › Research › peer-review

Standard

Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates. / Villadsen, Klaus; Martos Maldonado, Manuel Cristo; Jensen, Knud Jørgen; Thygesen, Mikkel Boas.

In: ChemBioChem, Vol. 18, No. 7, 2017, p. 574-612.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Villadsen, K, Martos Maldonado, MC, Jensen, KJ & Thygesen, MB 2017, 'Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates', ChemBioChem, vol. 18, no. 7, pp. 574-612. https://doi.org/10.1002/cbic.201600582

APA

Villadsen, K., Martos Maldonado, M. C., Jensen, K. J., & Thygesen, M. B. (2017). Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates. ChemBioChem, 18(7), 574-612. https://doi.org/10.1002/cbic.201600582

Vancouver

Villadsen K, Martos Maldonado MC, Jensen KJ, Thygesen MB. Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates. ChemBioChem. 2017;18(7):574-612. https://doi.org/10.1002/cbic.201600582

Author

Villadsen, Klaus ; Martos Maldonado, Manuel Cristo ; Jensen, Knud Jørgen ; Thygesen, Mikkel Boas. / Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates. In: ChemBioChem. 2017 ; Vol. 18, No. 7. pp. 574-612.

Bibtex

@article{f0c2250e473a411e8b65e93fd997c5e6,
title = "Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates",
abstract = "Glycobiology is the comprehensive biological investigation of carbohydrates. The study of the role and function of complex carbohydrates often requires the attachment of carbohydrates to surfaces, their tagging with fluorophores, or their conversion into natural or non-natural glycoconjugates, such as glycopeptides or glycolipids. Glycobiology and its “omics”, glycomics, require easy and robust chemical methods for the construction of these glycoconjugates. This review gives an overview of the rapidly expanding field of chemical reactions that selectively convert unprotected carbohydrates into glycoconjugates through the anomeric position. The discussion is divided in terms of the anomeric bond type of the newly formed glycoconjugates, including O-, N-, S-, and C-glycosides.",
keywords = "carbohydrate–protein interactions, glycan tagging, glycobiology, glycoconjugates, glycoproteins",
author = "Klaus Villadsen and {Martos Maldonado}, {Manuel Cristo} and Jensen, {Knud J{\o}rgen} and Thygesen, {Mikkel Boas}",
year = "2017",
doi = "10.1002/cbic.201600582",
language = "English",
volume = "18",
pages = "574--612",
journal = "ChemBioChem",
issn = "1439-4227",
publisher = "Wiley - V C H Verlag GmbH & Co. KGaA",
number = "7",

}

RIS

TY - JOUR

T1 - Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

AU - Villadsen, Klaus

AU - Martos Maldonado, Manuel Cristo

AU - Jensen, Knud Jørgen

AU - Thygesen, Mikkel Boas

PY - 2017

Y1 - 2017

N2 - Glycobiology is the comprehensive biological investigation of carbohydrates. The study of the role and function of complex carbohydrates often requires the attachment of carbohydrates to surfaces, their tagging with fluorophores, or their conversion into natural or non-natural glycoconjugates, such as glycopeptides or glycolipids. Glycobiology and its “omics”, glycomics, require easy and robust chemical methods for the construction of these glycoconjugates. This review gives an overview of the rapidly expanding field of chemical reactions that selectively convert unprotected carbohydrates into glycoconjugates through the anomeric position. The discussion is divided in terms of the anomeric bond type of the newly formed glycoconjugates, including O-, N-, S-, and C-glycosides.

AB - Glycobiology is the comprehensive biological investigation of carbohydrates. The study of the role and function of complex carbohydrates often requires the attachment of carbohydrates to surfaces, their tagging with fluorophores, or their conversion into natural or non-natural glycoconjugates, such as glycopeptides or glycolipids. Glycobiology and its “omics”, glycomics, require easy and robust chemical methods for the construction of these glycoconjugates. This review gives an overview of the rapidly expanding field of chemical reactions that selectively convert unprotected carbohydrates into glycoconjugates through the anomeric position. The discussion is divided in terms of the anomeric bond type of the newly formed glycoconjugates, including O-, N-, S-, and C-glycosides.

KW - carbohydrate–protein interactions

KW - glycan tagging

KW - glycobiology

KW - glycoconjugates

KW - glycoproteins

U2 - 10.1002/cbic.201600582

DO - 10.1002/cbic.201600582

M3 - Review

C2 - 28067438

AN - SCOPUS:85014036661

VL - 18

SP - 574

EP - 612

JO - ChemBioChem

JF - ChemBioChem

SN - 1439-4227

IS - 7

ER -

ID: 176610067