Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: A systematic review and meta-analysis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults : A systematic review and meta-analysis. / Rønnstad, Amalie Thorsti Møller; Halling-Overgaard, Anne-Sofie; Hamann, Carsten R; Skov, Lone; Egeberg, Alexander; Thyssen, Jacob P.

In: Journal of the American Academy of Dermatology, Vol. 79, No. 3, 2018, p. 448-456.e30.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Rønnstad, ATM, Halling-Overgaard, A-S, Hamann, CR, Skov, L, Egeberg, A & Thyssen, JP 2018, 'Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: A systematic review and meta-analysis', Journal of the American Academy of Dermatology, vol. 79, no. 3, pp. 448-456.e30. https://doi.org/10.1016/j.jaad.2018.03.017

APA

Rønnstad, A. T. M., Halling-Overgaard, A-S., Hamann, C. R., Skov, L., Egeberg, A., & Thyssen, J. P. (2018). Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: A systematic review and meta-analysis. Journal of the American Academy of Dermatology, 79(3), 448-456.e30. https://doi.org/10.1016/j.jaad.2018.03.017

Vancouver

Rønnstad ATM, Halling-Overgaard A-S, Hamann CR, Skov L, Egeberg A, Thyssen JP. Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: A systematic review and meta-analysis. Journal of the American Academy of Dermatology. 2018;79(3):448-456.e30. https://doi.org/10.1016/j.jaad.2018.03.017

Author

Rønnstad, Amalie Thorsti Møller ; Halling-Overgaard, Anne-Sofie ; Hamann, Carsten R ; Skov, Lone ; Egeberg, Alexander ; Thyssen, Jacob P. / Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults : A systematic review and meta-analysis. In: Journal of the American Academy of Dermatology. 2018 ; Vol. 79, No. 3. pp. 448-456.e30.

Bibtex

@article{a927e97eb67e42bbbcb0b4ab7144137b,
title = "Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: A systematic review and meta-analysis",
abstract = "BACKGROUND: Atopic dermatitis (AD) has been associated with anxiety and depression, but the magnitude of the alleged association is unknown.OBJECTIVE: To perform a systematic review and meta-analysis of the association between AD in children and adults and, respectively, depression, anxiety, and suicidal behavior.METHODS: The medical databases PubMed, Embase, and PsychINFO were searched.RESULTS: There was a significant association between adult AD and, respectively, depression (pooled odds ratio [OR], 2.19; 95% confidence interval [CI], 1.87-2.57) and anxiety (pooled OR, 2.19; 95% CI, 1.75-2.73). AD was also associated with depression in children (pooled OR, 1.27; 95% CI, 1.12-1.45); few data were available for anxiety. A positive association was found between AD in adults and adolescents and suicidal ideation (pooled OR, 4.32; 95% CI, 1.93-9.66). Only a few studies examined the risk of completed suicide, but the majority showed a positive association between completed suicide and AD.LIMITATIONS: Included studies used different definitions of depression and anxiety, and few studies examined the severity of AD.CONCLUSION: Depression, anxiety, and suicidal ideation should be considered by doctors when treating patients with AD. Because AD disease improvement appears to reduce these risks, this should be a priority.",
keywords = "Adult, Anxiety/epidemiology, Child, Comorbidity, Depression/epidemiology, Dermatitis, Atopic/epidemiology, Humans, Odds Ratio, Suicidal Ideation, Suicide, Attempted",
author = "R{\o}nnstad, {Amalie Thorsti M{\o}ller} and Anne-Sofie Halling-Overgaard and Hamann, {Carsten R} and Lone Skov and Alexander Egeberg and Thyssen, {Jacob P.}",
year = "2018",
doi = "10.1016/j.jaad.2018.03.017",
language = "English",
volume = "79",
pages = "448--456.e30",
journal = "American Academy of Dermatology. Journal",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults

T2 - A systematic review and meta-analysis

AU - Rønnstad, Amalie Thorsti Møller

AU - Halling-Overgaard, Anne-Sofie

AU - Hamann, Carsten R

AU - Skov, Lone

AU - Egeberg, Alexander

AU - Thyssen, Jacob P.

PY - 2018

Y1 - 2018

N2 - BACKGROUND: Atopic dermatitis (AD) has been associated with anxiety and depression, but the magnitude of the alleged association is unknown.OBJECTIVE: To perform a systematic review and meta-analysis of the association between AD in children and adults and, respectively, depression, anxiety, and suicidal behavior.METHODS: The medical databases PubMed, Embase, and PsychINFO were searched.RESULTS: There was a significant association between adult AD and, respectively, depression (pooled odds ratio [OR], 2.19; 95% confidence interval [CI], 1.87-2.57) and anxiety (pooled OR, 2.19; 95% CI, 1.75-2.73). AD was also associated with depression in children (pooled OR, 1.27; 95% CI, 1.12-1.45); few data were available for anxiety. A positive association was found between AD in adults and adolescents and suicidal ideation (pooled OR, 4.32; 95% CI, 1.93-9.66). Only a few studies examined the risk of completed suicide, but the majority showed a positive association between completed suicide and AD.LIMITATIONS: Included studies used different definitions of depression and anxiety, and few studies examined the severity of AD.CONCLUSION: Depression, anxiety, and suicidal ideation should be considered by doctors when treating patients with AD. Because AD disease improvement appears to reduce these risks, this should be a priority.

AB - BACKGROUND: Atopic dermatitis (AD) has been associated with anxiety and depression, but the magnitude of the alleged association is unknown.OBJECTIVE: To perform a systematic review and meta-analysis of the association between AD in children and adults and, respectively, depression, anxiety, and suicidal behavior.METHODS: The medical databases PubMed, Embase, and PsychINFO were searched.RESULTS: There was a significant association between adult AD and, respectively, depression (pooled odds ratio [OR], 2.19; 95% confidence interval [CI], 1.87-2.57) and anxiety (pooled OR, 2.19; 95% CI, 1.75-2.73). AD was also associated with depression in children (pooled OR, 1.27; 95% CI, 1.12-1.45); few data were available for anxiety. A positive association was found between AD in adults and adolescents and suicidal ideation (pooled OR, 4.32; 95% CI, 1.93-9.66). Only a few studies examined the risk of completed suicide, but the majority showed a positive association between completed suicide and AD.LIMITATIONS: Included studies used different definitions of depression and anxiety, and few studies examined the severity of AD.CONCLUSION: Depression, anxiety, and suicidal ideation should be considered by doctors when treating patients with AD. Because AD disease improvement appears to reduce these risks, this should be a priority.

KW - Adult

KW - Anxiety/epidemiology

KW - Child

KW - Comorbidity

KW - Depression/epidemiology

KW - Dermatitis, Atopic/epidemiology

KW - Humans

KW - Odds Ratio

KW - Suicidal Ideation

KW - Suicide, Attempted

U2 - 10.1016/j.jaad.2018.03.017

DO - 10.1016/j.jaad.2018.03.017

M3 - Journal article

C2 - 30119868

VL - 79

SP - 448-456.e30

JO - American Academy of Dermatology. Journal

JF - American Academy of Dermatology. Journal

SN - 0190-9622

IS - 3

ER -

ID: 217512894