[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice
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[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice. / Jensen, Mette Munk; Erichsen, Kamille Dumong; Johnbeck, Camilla Bardram; Björkling, Fredrik; Madsen, Jacob; Jensen, Peter Buhl; Sehested, Maxwell; Højgaard, Liselotte; Kjær, Andreas.
In: B M C Cancer, Vol. 13, 168, 2013, p. 1-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - [18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice
AU - Jensen, Mette Munk
AU - Erichsen, Kamille Dumong
AU - Johnbeck, Camilla Bardram
AU - Björkling, Fredrik
AU - Madsen, Jacob
AU - Jensen, Peter Buhl
AU - Sehested, Maxwell
AU - Højgaard, Liselotte
AU - Kjær, Andreas
PY - 2013
Y1 - 2013
N2 - Belinostat is a histone deacetylase inhibitor with anti-tumor effect in several pre-clinical tumor models and clinical trials. The aim of the study was to evaluate changes in cell proliferation and glucose uptake by use of 3'-deoxy-3'-[(18)F]fluorothymidine ([18F]FLT) and 2-deoxy-2-[(18)F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) following treatment with belinostat in ovarian cancer in vivo models.
AB - Belinostat is a histone deacetylase inhibitor with anti-tumor effect in several pre-clinical tumor models and clinical trials. The aim of the study was to evaluate changes in cell proliferation and glucose uptake by use of 3'-deoxy-3'-[(18)F]fluorothymidine ([18F]FLT) and 2-deoxy-2-[(18)F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) following treatment with belinostat in ovarian cancer in vivo models.
U2 - 10.1186/1471-2407-13-168
DO - 10.1186/1471-2407-13-168
M3 - Journal article
C2 - 23548101
VL - 13
SP - 1
EP - 9
JO - B M C Cancer
JF - B M C Cancer
SN - 1471-2407
M1 - 168
ER -
ID: 45864120