Xueyuan Leng

Xueyuan Leng


  • Duxin Group

    Blegdamsvej 3B, 2200 København N., Bygning 6, Building: 06-3-42

    Phone: +45 35 33 36 05

Fields of interest

  • Molecular Biology
  • Eukaryotic Replication
  • Eukaryotic Transcription
  • DNA Damage Repair
  • Plant Science
  • Cell Biology


Current research

DNA damage repair and eukaryotic replication

  • DNA-protein crosslink (DPC) repair
  • DNA damage pathway
  • Eukaryotic replicaiton

Transcription Kinetics in Plants

Functional gene expression is crucial for plant development, by which plants transform from zygotes into multi-cellular living forms. RNA polymerase II (Pol II) plays an irreplaceable role in ensuring function gene expression by conducting the transcription of all genes and coordinating their co-transcriptional mRNA processing events (i.e. splicing). Recently, A kinetic model of transcription offers a better way to understand the connection between transcription and co-transcriptional events. However, obtaining direct support for the biological significance of the kinetic model is often challenging due to pleiotropic effects of perturbing transcription. The transcription elongation speed is a core parameter in the kinetic model of transcription, which is tightly linked to co-transcriptional events. To address the biological significance of transcription speed in plant development we are focusing on the transcription kinetics of Pol II in model plant Arabidopsis

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