Walden Bjørn-Yoshimoto

Walden Bjørn-Yoshimoto

Assistant professor


  1. 2022
  2. Published

    (S)-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist

    Poulie, Christian Bernard Matthijs, Larsen, Y., Leteneur, C., Barthet, G., Bjørn-Yoshimoto, Walden, Malhaire, F., Nielsen, B., Pin, J. P., Mulle, C., Pickering, Darryl S & Bunch, Lennart, 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1580–1587

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins

    Koch, T. L., Ramiro, I. B. L., Flórez Salcedo, P., Engholm, Ebbe, Jensen, Knud Jørgen, Chase, K., Olivera, B. M., Bjørn-Yoshimoto, Walden, Safavi-hemami, H. & True, J. (ed.), 2022, In: Molecular Biology and Evolution. 39, 4, 20 p., msac075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

    Ramiro, I. B. L., Bjørn-Yoshimoto, Walden, Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner-Osborne, Hans, Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2020
  6. Published

    Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

    Bjørn-Yoshimoto, Walden, Ramiro, I. B. L., Yandell, M., McIntosh, J. M., Olivera, B. M., Ellgaard, Lars & Safavi, Helena, 2020, In: Biomedicines. 8, 8, 22 p., 235.

    Research output: Contribution to journalReviewResearchpeer-review

  7. 2019
  8. Published

    Design and Synthesis of 2,3-trans-Proline Analogs as Ligands for the Ionotropic Glutamate Receptors and the Excitatory Amino Acid Transporters

    Poulie, Christian Bernard Matthijs, Alcaide Lopez, A., Krell-Jørgensen, M. P., Larsen, Y., Astier, E., Bjørn-Yoshimoto, Walden, Yi, F., Syrenne, J. T., Storgaard, M., Nielsen, Birgitte, Frydenvang, Karla Andrea, Jensen, Anders A., Hansen, K. B., Pickering, Darryl S & Bunch, Lennart, 19 Jun 2019, In: A C S Chemical Neuroscience. 10, 6, p. 2989-3007 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. 2018
  11. Published

    5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

    Peng, Y., McCorvy, J. D., Harpsøe, Kasper, Lansu, K., Yuan, S., Popov, P., Qu, L., Pu, M., Che, T., Nikolajsen, L. F., Huang, X., Wu, Y., Shen, L., Bjørn-Yoshimoto, Walden, Ding, K., Wacker, D., Han, G. W., Cheng, J., Katritch, V., Jensen, Anders A., Hanson, M. A., Zhao, S., Gloriam, David E., Roth, B. L., Stevens, R. C. & Liu, Z., 2018, In: Cell. 172, 4, p. 719-730 P719-730.E14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    Improving heterologous production of phenylpropanoids in Saccharomyces cerevisiae by tackling an unwanted side reaction of Tsc13, an endogenous double-bond reductase

    Lehka, B. J., Eichenberger, M., Bjørn-Yoshimoto, Walden, Vanegas, K. G., Buijs, N., Jensen, N. B., Dyekjær, J. D., Jenssen, H., Simon, E. & Naesby, M., Jan 2017, In: F E M S Yeast Research. 17, 1, 12 p., fox004.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2016
  15. Published

    Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102

    Haym, I., Huynh, Tri Hien Viet, Hansen, S. W., Pedersen, M. H. F., Ruiz, J. A., Erichsen, M. N., Gynther, M., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 17 Feb 2016, In: ChemMedChem. 11, 4, p. 403-19 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    New Insight into the Structure-Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors UCPH-101 and UCPH-102

    Hansen, S. W., Erichsen, M. N., Huynh, Tri Hien Viet, Ruiz, J. A., Haym, I., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Hansen, Jeanette Venla, Storgaard, M., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 17 Feb 2016, In: ChemMedChem. 11, 4, p. 382-402 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III

    Huynh, Tri Hien Viet, Erichsen, M. N., Tora, A. S., Goudet, C., Sagot, E., Assaf, Z., Thomsen, C., Brodbeck, R., Stensbøl, T. B., Bjørn-Yoshimoto, Walden, Nielsen, Birgitte, Pin, J., Gefflaut, T. & Bunch, Lennart, 11 Feb 2016, In: Journal of Medicinal Chemistry. 59, 3, p. 914-24 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Beta-Sulfonamido Functionalized Aspartate Analogs as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype-Selectivity Profiles Arising from Subtle Structural Differences

    Hansen, J. C., Bjørn-Yoshimoto, Walden, Bisballe, N., Nielsen, Birgitte, Jensen, Anders A. & Bunch, Lennart, 2016, In: Journal of Medicinal Chemistry. 59, p. 8771-8786 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Bioavailability studies and in vitro profiling of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-102)

    Haym, I., Huyng, T. H. V., Hansen, S. W., Pedersen, M. H. F., Ruiz, J. A., Erichsen, M. N., Gynther, M., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 2016, In: ChemMedChem. 11, 4, p. 403-419 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity-Relationship Study

    Hansen, S. W., Erichsen, M. N., Fu, B., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Hansen, J. C., Jensen, Anders A. & Bunch, Lennart, 2016, In: Journal of Medicinal Chemistry. 59, 19, p. 8757-8770 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III

    Huynh, T. H. V., Erichsen, M. N., Tora, A. S., Goudet, C., Sagot, E., Assaf, Z., Thomsen, C., Brodbeck, R., Stensbol, T. B., Bjørn-Yoshimoto, Walden, Nielsen, Birgitte, Pin, J., Gefflaut, T. & Bunch, Lennart, 2016, In: Journal of Medicinal Chemistry. 59, 3, p. 914-924 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    New insights into the structure-activity-relationship of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitors UCPH-101 and UCPH-102

    Hansen, S. W., Erichsen, M. N., Huynh, T. H. V., Ruiz, J. A., Haym, I., Bjørn-Yoshimoto, Walden, Abrahamsen, B., Hansen, J., Storgaard, M., Eriksen, A. L., Jensen, Anders A. & Bunch, Lennart, 2016, In: ChemMedChem. 11, p. 382-402 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The importance of the excitatory amino acid transporter 3 (EAAT3)

    Bjørn-Yoshimoto, Walden & Underhill, S. M., 2016, In: Neurochemistry International. 98, p. 4–18 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2015
  25. Published

    Excitatory amino acid transporters: recent insights into molecular mechanisms, novel modes of modulation and new therapeutic possibilities

    Jensen, Anders A., Fahlke, C., Bjørn-Yoshimoto, Walden & Bunch, Lennart, 2015, In: Current Opinion in Pharmacology. 20, p. 116-123 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2010
  27. Published

    Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons

    Eriksen, J., Bjørn-Yoshimoto, Walden, Jørgensen, T. N., Newman, A. H. & Gether, Ulrik, 2010, In: Journal of Biological Chemistry. 285, 35, p. 27289-301 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 49166531