Vibe Hallundbæk Østergaard
Associate Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
- 2003
- Published
A human topoisomerase IIα heterodimer with only one ATP binding site can go through successive catalytic cycles
Skouboe, C., Bjergbaek, L., Østergaard, Vibe Hallundbæk, Larsen, M. K., Knudsen, B. R. & Andersen, A. H., 21 Feb 2003, In: Journal of Biological Chemistry. 278, 8, p. 5768-5774 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
The Transducer Domain Is Important for Clamp Operation in Human DNA Topoisomerase IIα
Østergaard, Vibe Hallundbæk, Bjergbaek, L., Skouboe, C., Giangiacomo, L., Knudsen, B. R. & Andersen, A. H., 16 Jan 2004, In: Journal of Biological Chemistry. 279, 3, p. 1684-1691 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting the cell-killing mechanism of the topoisomerase II-targeting drug ICRF-193
Østergaard, Vibe Hallundbæk, Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28100-28105 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hindering the strand passage reaction of human topoisomerase IIα without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp
Østergaard, Vibe Hallundbæk, Giangiacomo, L., Bjergbaek, L., Knudsen, B. R. & Andersen, A. H., 2 Jul 2004, In: Journal of Biological Chemistry. 279, 27, p. 28093-28099 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40
Simpson, L. J., Ross, A. L., Szüts, D., Alviani, C. A., Østergaard, Vibe Hallundbæk, Patel, K. J. & Sale, J. E., 1 Sep 2006, In: EMBO Reports. 7, 9, p. 927-932 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair
Østergaard, Vibe Hallundbæk, Langevin, F., Kuiken, H. J., Pace, P., Niedzwiedz, W., Simpson, L. J., Ohzeki, M., Takata, M., Sale, J. E. & Patel, K. J., 14 Dec 2007, In: Molecular Cell. 28, 5, p. 798-809 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
The QTK Loop is Essential for the Communication between the N-Terminal ATPase Domain and the Central Cleavage-Ligation Region in Human Topoisomerase IIα
Bendsen, S., Østergaard, Vibe Hallundbæk, Skouboe, C., Brinch, M., Knudsen, B. R. & Andersen, A. H., 2009, In: Biochemistry. 48, 27, p. 6508-6515 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination
Germann, S. M., Østergaard, Vibe Hallundbæk, Haas, C., Salis, P., Motegi, A. & Lisby, Michael, 2011, In: D N A Repair. 10, 2, p. 210-224 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells
Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The genetic and biochemical basis of FANCD2 Monoubiquitination
Rajendra, E., Østergaard, Vibe Hallundbæk, Langevin, F., Wang, M., Dornan, G. L., Patel, K. J. & Passmore, L. A., 2014, In: Molecular Cell. 54, 5, p. 858-869 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11903628
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The genetic and biochemical basis of FANCD2 Monoubiquitination
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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity
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FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells
Research output: Contribution to journal › Journal article › Research › peer-review
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