Thomas Werge

Thomas Werge

Clinical Professor

Member of:

  • Psychiatry


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  1. Published

    The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

    Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The genetic history of Scandinavia from the Roman Iron Age to the present

    Rodríguez-Varela, R., Moore, K. H. S., Ebenesersdóttir, S. S., Kilinc, G. M., Kjellström, A., Papmehl-Dufay, L., Alfsdotter, C., Berglund, B., Alrawi, L., Kashuba, N., Sobrado, V., Lagerholm, V. K., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T. & 24 others, Munters, A. R., Bernhardsson, C., Skar, B., Christophersen, A., Turner-Walker, G., Gopalakrishnan, Shyam, Daskalaki, E., Omrak, A., Pérez-Ramallo, P., Skoglund, P., Girdland-Flink, L., Gunnarsson, F., Hedenstierna-Jonson, C., Gilbert, M Thomas P, Lidén, K., Jakobsson, M., Einarsson, L., Victor, H., Krzewińska, M., Zachrisson, T., Storå, J., Stefánsson, K., Helgason, A. & Götherström, A., 2023, In: Cell. 186, 1, p. 32-46.e19

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The genetic structure of Norway

    Mattingsdal, M., Ebenesersdóttir, S. S., Moore, K. H. S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kockum, I., Olsson, T., Alfredsson, L., Helgason, A., Stefánsson, K. & Hovig, E., 2021, In: European Journal of Human Genetics. 29, p. 1710–1718

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders

    Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The impact of CYP2D6 and CYP2C19 polymorphisms on suicidal behavior and substance abuse disorder among patients with schizophrenia: a retrospective study

    Kobylecki, C. J., Hansen, T., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B., Werge, T. M., Kobylecki, C. J., Hansen, T. F., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B. & Werge, Thomas, 2008, In: Therapeutic Drug Monitoring. 30, 3, p. 265-70 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The influence of genetic constitution on migraine drug responses

    Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys

    Andersen, M. B., Fink-Jensen, Anders, Peacock, L., Gerlach, J., Bymaster, F., Lundbaek, J. A. & Werge, Thomas, 2003, In: Neuropsychopharmacology. 28, 6, p. 1168-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The population genomic legacy of the second plague pandemic

    Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The prevalence and early life determinants of mental disorders in school aged children: 11 years follow up of the CCC 2000 birth cohort study. Poster presentation XVII.ESCAP International Congress Budapest August 2009

    Jeppesen, Pia, Fagerlund, Birgitte, Glenthøj, Birte Yding, Werge, Thomas, Linneberg, Allan René, Jørgensen, T. & Skovgaard, A. M., 2009. 0 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  10. Published

    The sequences of 150,119 genomes in the UK Biobank

    Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, Sverrisson, S. T., Sigurdsson, B., Gudjonsson, S. A., Sigurdsson, G. T., Halldorsson, G. H., Sveinbjornsson, G., Norland, K., Styrkarsdottir, U., Magnusdottir, D. N., Snorradottir, S., Kristinsson, K., Sobech, E., Pedersen, Ole Birger Vesterager, Brunak, Søren, Ostrowski, Sisse Rye, Banasik, Karina, Burgdorf, Kristoffer Sølvsten, Didriksen, Maria, Hansen, Thomas Folkmann, Hjalgrim, Henrik, Jemec, Gregor, Jennum, Poul, Jo­hans­son, Pär In­ge­mar , Ostrowski, Sisse Rye, Ullum, H., Werge, Thomas & DBDS Genetic Consortium, D. G. C., 2022, In: Nature. 607

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys

    Brandt-Christensen, M., Andersen, M. B., Fink-Jensen, Anders, Werge, Thomas & Gerlach, J., 2006, In: Journal of Neural Transmission. 113, 1, p. 11-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis

    Saetre, P., Lundmark, P., Wang, August Gabriel, Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Djurovic, S., Melle, I., Andreassen, O. A., Werge, Thomas, Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 387-96 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia

    van Schijndel, J. E., van Loo, K. M. J., van Zweeden, M., Djurovic, S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kallunki, P., Pedersen, J. T. & Martens, G. J. M., 2009, In: Journal of Psychiatric Research. 43, 15, p. 1195-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations

    Gordon, A., Forsingdal, A., Klewe, I. V., Nielsen, J., Didriksen, M., Werge, Thomas & Geschwind, D. H., 2021, In: Molecular Psychiatry. 26, p. 1520–1534

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

    Lahrouchi, N., Tadros, R., Crotti, L., Mizusawa, Y., Postema, P. G., Beekman, L., Walsh, R., Hasegawa, K., Barc, J., Ernsting, M., Turkowski, K. L., Mazzanti, A., Beckmann, B. M., Shimamoto, K., Diamant, U-B., Wijeyeratne, Y. D., Kucho, Y., Robyns, T., Ishikawa, T., Arbelo, E. & 86 others, Christiansen, M., Winbo, A., Jabbari, R., Lubitz, S. A., Steinfurt, J., Rudic, B., Loeys, B., Shoemaker, M. B., Weeke, P. E., Pfeiffer, R., Davies, B., Andorin, A., Hofman, N., Dagradi, F., Pedrazzini, M., Tester, D. J., Bos, J. M., Sarquella-Brugada, G., Campuzano, Ó., Platonov, P. G., Stallmeyer, B., Zumhagen, S., Nannenberg, E. A., Veldink, J. H., van den Berg, L. H., Al-Chalabi, A., Shaw, C. E., Shaw, P. J., Morrison, K. E., Andersen, P. M., Müller-Nurasyid, M., Cusi, D., Barlassina, C., Galan, P., Lathrop, M., Munter, M., Werge, Thomas, Ribasés, M., Aung, T., Khor, C. C., Ozaki, M., Lichtner, P., Meitinger, T., van Tintelen, J. P., Hoedemaekers, Y., Denjoy, I., Leenhardt, A., Napolitano, C., Shimizu, W., Schott, J., Gourraud, J., Makiyama, T., Ohno, S., Itoh, H., Krahn, A. D., Antzelevitch, C., Roden, D. M., Saenen, J., Borggrefe, M., Odening, K. E., Ellinor, P. T., Tfelt-Hansen, Jacob, Skinner, J. R., van den Berg, M. P., Olesen, Morten Steen Salling, Brugada, J., Brugada, R., Makita, N., Breckpot, J., Yoshinaga, M., Behr, E. R., Rydberg, A., Aiba, T., Kääb, S., Priori, S. G., Guicheney, P., Tan, H. L., Newton-Cheh, C., Ackerman, M. J., Schwartz, P. J., Schulze-Bahr, E., Probst, V., Horie, M., Wilde, A. A., Tanck, M. W. T. & Bezzina, C. R., 2020, In: Circulation. 142, 4, p. 324-338

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

    Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M., Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, Thomas, Lage, K. & Regeneron Genetics Center, R. G. C., 2021, In: Nature Communications. 12, 5276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes

    Søgaard, R., Ebert, B., Klærke, Dan Arne, Werge, Thomas, Søgaard, R., Ebert, B., Klaerke, D. & Werge, Thomas, 2009, In: B B A - Biomembranes. 1788, 5, p. 1073-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers

    Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 30 Dec 2010, In: Psychiatry Research. 180, 2-3, p. 63-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study

    Jönsson, E. G., Larsson, K., Vares, M., Hansen, T., Wang, August Gabriel, Djurovic, S., Rønningen, K. S., Andreassen, O. A., Agartz, I., Werge, Thomas, Terenius, L. & Hall, H., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 6, p. 976-82 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family

    Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia

    Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, Andreassen, O. A., Werge, Thomas, Hall, H., Agartz, I., Terenius, L. & Jönsson, E. G., 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Usefulness of the SNP microarray technology to identify rare mutations in the case of perinatal death

    Hoeffding, L. K., Kock, K. F., Johnsen, I. G., Hansen, Thomas Folkmann & Werge, Thomas, Jan 2015, In: Case Reports in Perinatal Medicine.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Using electronic patient records to discover disease correlations and stratify patient cohorts

    Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice

    Jürgens, G., Jacobsen, C. B., Rasmussen, H. B., Werge, T., Nordentoft, Merete, Andersen, S. E. & Werge, Thomas, 2012, In: Acta Psychiatrica Scandinavica. 125, 3, p. 228-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight

    iPSYCH-Broad ASD Group, I. A. G., 15 Apr 2019, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1770, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

    Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, Skogstrand, K., Peng, S., Thompson, W. K., Appadurai, V., Lawlor, D. A., Kalliala, I., Power, C., McCarthy, M. I., Boyd, H. A., Marazita, M. L., Hakonarson, H., Hayes, M. G., Scholtens, D. M., Rivadeneira, F., Jaddoe, V. W. V., Vinding, R. K., Bisgaard, H., Knight, B. A., Pahkala, K., Raitakari, O., Helgeland, Ø., Johansson, S., Njølstad, P. R., Fadista, J., Schork, A. J., Nudel, R., Miller, D. E., Chen, X., Weirauch, M. T., Mortensen, P. B., Børglum, A. D., Nordentoft, Merete, Mors, O., Hao, K., Ryckman, K. K., Hougaard, D. M., Kottyan, L. C., Pennell, C. E., Lyytikainen, L., Bønnelykke, Klaus, Vrijheid, M., Felix, J. F., Lowe, W. L., Grant, S. F. A., Hyppönen, E., Jacobsson, B., Jarvelin, M., Muglia, L. J., Murray, J. C., Freathy, R. M., Werge, Thomas, Melbye, M., Buil, A. & Feenstra, B., 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Variation in the purinergic P2RX(7) receptor gene and schizophrenia

    Hansen, T., Jakobsen, K. D., Fenger, M., Nielsen, J., Krane, K., Fink-Jensen, Anders, Lublin, H., Ullum, H., Timm, S., Wang, August Gabriel, Jørgensen, Niklas Rye & Werge, Thomas, 2008, In: Schizophrenia Research. 104, 1-3, p. 146-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 34394780