Rasmus Nielsen

Rasmus Nielsen

Professor

ORCID: 0000-0003-0513-6591

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  1. Published

    A draft genome sequence of the elusive giant squid, Architeuthis dux

    da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, Osório, H., Winkelmann, I., Simakov, O., Rasmussen, Simon, Rahman, M. Z., Pisani, D., Vinther, J., Jarvis, E., KU, thw266, Strugnell, J. M., Castro, L. F. C., Fedrigo, O., Patricio, M., Li, Q., Rocha, S., Antunes, A., Wu, Y., Ma, B., Sanges, R., Vinar, T., Blagoev, B., Sicheritz-Pontén, Thomas, Nielsen, Rasmus & Gilbert, M Thomas P, 2020, In: GigaScience. 9, 1, 12 p., giz152.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater

    Zhou, X., Guang, X., Sun, D., Xu, S., Li, M., Seim, I., Jie, W., Yang, L., Zhu, Q., Xu, J., Gao, Q., Kaya, A., Dou, Q., Chen, B., Ren, W., Li, S., Zhou, K., Gladyshev, V. N., Nielsen, R., Fang, X. & 1 others, Yang, G., 2018, In: Nature Communications. 9, 8 p., 1276.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Molecular footprints of aquatic adaptation including bone mass changes in cetaceans

    Zhou, X., Sun, D., Guang, X., Ma, S., Fang, X., Mariotti, M., Nielsen, Rasmus, Gladyshev, V. N. & Yang, G., 2018, In: Genome Biology and Evolution. 10, 3, p. 967-975 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    DistAngsd: Fast and Accurate Inference of Genetic Distances for Next-Generation Sequencing Data

    Zhao, Lei, Nielsen, Rasmus & Korneliussen, Thorfinn Sand, 2022, In: Molecular Biology and Evolution. 39, 6, 14 p., msac119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. The Tibetan-Yi region is both a corridor and a barrier for human gene flow

    Zhang, Z., Zhang, Y., Wang, Y., Zhao, Z., Yang, M., Zhang, L., Zhou, B., Xu, B., Zhang, H., Chen, T., Dai, W., Zhou, Y., Shi, S., Nielsen, Rasmus, Li, S. C. & Li, S., 2022, In: Cell Reports. 39, 4, 16 p., 110720.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The history and evolution of the Denisovan-EPAS1 haplotype in Tibetans

    Zhang, X., Witt, K. E., Banuelos, M. M., Ko, A., Yuan, K., Xu, S., Nielsen, Rasmus & Huerta-Sanchez, E., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 22, 9 p., 2020803118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The genetic architecture of phenotypic diversity in the Betta fish (Betta splendens)

    Zhang, W., Wang, H., Brandt, D. Y. C., Hu, B., Sheng, J., Wang, M., Luo, H., Li, Y., Guo, S., Sheng, B., Zeng, Q., Peng, K., Zhao, D., Jian, S., Wu, D., Wang, J., Zhao, G., Ren, J., Shi, W., van Esch, J. H. M. & 3 others, Klingunga, S., Nielsen, Rasmus & Hong, Y., 2022, In: Science Advances. 8, 38, 13 p., eabm4955.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Evaluation of an Improved Branch-Site Likelihood Method for Detecting Positive Selection at the Molecular Level

    Zhang, J., Nielsen, Rasmus & Yang, Z., 2005, In: Molecular Biology and Evolution. 22, 12, p. 2472-2479

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Exploring variation in the d(N)/d(S) ratio among sites and lineages using mutational mappings: applications to the influenza virus

    Zhai, W., Slatkin, M. & Nielsen, Rasmus, 2007, In: Journal of Molecular Evolution. 65, 3, p. 340-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    An investigation of the statistical power of neutrality tests based on comparative and population genetic data

    Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Looking for Darwin in Genomic Sequences-Validity and Success of Statistical Methods

    Zhai, W., Nielsen, Rasmus, Goldman, N. & Yang, Z., 2012, In: Molecular Biology and Evolution. 29, 10, p. 2889-2893 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Bottleneck and selection in the germline and maternal age influence transmission of mitochondrial DNA in human pedigrees

    Zaidi, A. A., Wilton, P. R., Su, M. S., Paul, I. M., Arbeithuber, B., Anthony, K., Nekrutenko, A., Nielsen, Rasmus & Makova, K. D., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25172-25178 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Bayesian estimation of the number of inversions in the history of two chromosomes

    York, T. L., Durrett, R. & Nielsen, Rasmus, 1 Dec 2002, In: Journal of Computational Biology. 9, 6, p. 805-818 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Bayesian and maximum likelihood estimation of genetic maps

    York, T. L., Durrett, R. T., Tanksley, S. & Nielsen, Rasmus, 2005, In: Genetics Research. 85, 2, p. 159-168

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dependence of paracentric inversion rate on tract length

    York, T. L., Durrett, R. & Nielsen, Rasmus, 2007, In: BMC Bioinformatics. 8, p. 115

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Sequencing of 50 human exomes reveals adaptation to high altitude

    Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, Shan, Y., Li, S., Yang, Q., Asan, G., Ni, P., Tian, G., Xu, J., Liu, X., Jiang, T., Wu, R., Zhou, G., Tang, M., Qin, J., Wang, T., Feng, S., Li, G., Huasang, G., Luosang, J., Wang, W., Chen, F., Wang, Y., Zheng, X., Li, Z., Bianba, Z., Yang, G., Wang, X., Tang, S., Gao, G., Yong, C., Luo, Z., Gusang, L., Cao, Z., Zhang, Q., Ouyang, W., Ren, X., Liang, H., Zheng, H., Huang, Y., Li, J., Bolund, L., Kristiansen, Karsten, Li, Y., Zhang, Y., Zhang, X., Li, R., Li, S., Yang, H., Nielsen, Rasmus, Wang, J. & Wang, J., 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Bayes Empirical Bayes Inference of Amino Acid Sites Under Positive Selection

    Yang, Z., Wong, W. S. W. & Nielsen, Rasmus, 2005, In: Molecular Biology and Evolution. 22, 4, p. 1107-1118

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Synonymous and nonsynonymous rate variation in nuclear genes of mammals

    Yang, Z. & Nielsen, Rasmus, 23 Apr 1998, In: Journal of Molecular Evolution. 46, 4, p. 409-418 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Mutation-selection models of codon substitution and their use to estimate selective strengths on codon usage

    Yang, Z. & Nielsen, Rasmus, 2008, In: Molecular Biology and Evolution. 25, 3, p. 568-79 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    In defense of statistical methods for detecting positive selection

    Yang, Z., Nielsen, Rasmus & Goldman, N., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 36, p. E95

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques

    Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., Zhuo, M. & 26 others, Wang, T., Huang, Y., Wei, L., Li, J., Wang, Z., Hu, H., Yang, P., Le, L., Stenson, P. D., Li, B., Liu, X., Ball, E. V., An, N., Huang, Q., Zhang, Y., Fan, W., Zhang, X., Li, Y., Wang, W., Katze, M. G., Su, B., Nielsen, Rasmus, Yang, H., Wang, J., Wang, X. & Wang, J., 2011, In: Nature Biotechnology. 29, 11, p. 1019-1023 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  22. Published

    Evaluation of methods for estimating coalescence times using ancestral recombination graphs

    Y C Brandt, D., Wei, X., Deng, Y., Vaughn, A. H. & Nielsen, Rasmus, 2022, In: Genetics. 221, 1, 13 p., iyac044.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)

    Xia, Q., Guo, Y., Zhang, Z., Li, D., Xuan, Z., Li, Z., Dai, F., Li, Y., Cheng, D., Li, R., Cheng, T., Jiang, T., Becquet, C., Xu, X., Liu, C., Zha, X., Fan, W., Lin, Y., Shen, Y., Jiang, L. & 38 others, Jensen, J., Hellmann, I., Tang, S., Zhao, P., Xu, H., Yu, C., Zhang, G., Li, J., Cao, J., Liu, S., He, N., Zhou, Y., Liu, H., Zhao, J., Ye, C., Du, Z., Pan, G., Zhao, A., Shao, H., Zeng, W., Wu, P., Li, C., Pan, M., Li, J., Yin, X., Li, D., Wang, J., Zheng, H., Wang, W., Zhang, X., Li, S., Yang, H., Lu, C., Nielsen, Rasmus, Zhou, Z., Wang, J., Xiang, Z. & Wang, J., 2009, In: Science. 326, 5951, p. 433-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Pervasive introgression facilitated domestication and adaptation in the Bos species complex

    Wu, D., Ding, X. D., Wang, S., Wójcik, J. M., Zhang, Y., Tokarska, M., Li, Y., Wang, M. S., Faruque, O., Nielsen, Rasmus, Zhang, Q. & Zhang, Y., 2018, In: Nature Ecology and Evolution. 2, 7, p. 1139-1145 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Identification of physicochemical selective pressure on protein encoding nucleotide sequences

    Wong, W. S. W., Sainudiin, R. & Nielsen, Rasmus, 2006, In: BMC Bioinformatics. 7, 10 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Finding cis-regulatory modules in Drosophila using phylogenetic hidden Markov models

    Wong, W. S. W. & Nielsen, Rasmus, 2007, In: Bioinformatics. 23, 16, p. 2031-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. The mind, the lab, and the field: Three kinds of populations in scientific practice

    Winther, Rasmus, Giordano, R., Edge, M. D. & Nielsen, Rasmus, 1 Aug 2015, In: Studies in History and Philosophy of Science Part C :Studies in History and Philosophy of Biological and Biomedical Sciences. 52, p. 12-21 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Introduction: Genomics and philosophy of race

    Winther, Rasmus, Millstein, R. L. & Nielsen, Rasmus, 1 Aug 2015, In: Studies in History and Philosophy of Science Part C :Studies in History and Philosophy of Biological and Biomedical Sciences. 52, p. 1-4 4 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  30. A population phylogenetic view of mitochondrial heteroplasmy

    Wilton, P. R., Zaidi, A., Makova, K. & Nielsen, Rasmus, 2018, In: Genetics. 208, 3, p. 1261-1274 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Natural Selection Reduced Diversity on Human Y Chromosomes

    Wilson Sayres, M. A., Lohmueller, K. E. & Nielsen, Rasmus, 2014, In: PLOS Genetics. 10, 1, 12 p., e1004064.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Simultaneous inference of selection and population growth from patterns of variation in the human genome

    Williamson, S. H., Hernandez, R., Fledel-Alon, A., Zhu, L., Nielsen, Rasmus & Bustamente, C. D., 2005, In: Proceedings of the National Academy of Science of the United States of America. 102, 22, p. 7882-7887

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Localizing recent adaptive evolution in the human genome

    Williamson, S. H., Hubisz, M. J., Clark, A. G., Payseur, B. A., Bustamante, C. D. & Nielsen, Rasmus, 2007, In: PLoS Genetics. 3, 6, p. e90

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Ancient biomolecules from deep ice cores reveal a forested southern Greenland.

    Willerslev, E., Cappellini, E., Boomsma, W. K., Nielsen, R., Hebsgaard, M. B., Brand, T. B., Hofreiter, M., Bunce, M., Poinar, H. N., Dahl-Jensen, D., Johnsen, S. J., Steffensen, J. P., Bennike, O., Schwenninger, J-L., Nathan, R., Armitage, S., de Hoog, C-J., Alfimov, V., Christl, M., Beer, J. & 10 others, Muscheler, R., Barker, J., Sharp, M., Penkman, K. E. H., Haile, J., Taberlet, P., Gilbert, M Thomas P, Casoli, A., Campani, E. & Collins, M. J., 2007, In: Science. 317, 5834, p. 111-114 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    CCR5-Delta 32 is deleterious in the homozygous state in humans

    Wei, X. & Nielsen, Rasmus, Jun 2019, In: Nature Medicine. 25, 6, p. 909-910

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Estimating population divergence time and phylogeny from single-nucleotide polymorphisms data with outgroup ascertainment bias

    Wang, Y. & Nielsen, Rasmus, 2012, In: Molecular Ecology. 21, 4, p. 974-986 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments

    Wang, Y., van der Hoeven, R. S., Nielsen, Rasmus, Mueller, L. A. & Tanksley, S. D., 2005, In: Theoretical and Applied Genetics. 112, 1, p. 72-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Ancient Hybridization with an Unknown Population Facilitated High-Altitude Adaptation of Canids

    Wang, M., Wang, S., Li, Y., Jhala, Y., Thakur, M., Otecko, N. O., Si, J., Chen, H., Shapiro, B., Nielsen, Rasmus, Zhang, Y., Wu, D. & Parsch, J. (ed.), 2020, In: MOLECULAR BIOLOGY AND EVOLUTION . 37, 9, p. 2616-2629

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The diploid genome sequence of an Asian individual

    Wang, J., Wang, W., Li, R., Li, Y., Tian, G., Goodman, L., Fan, W., Zhang, J., Li, J., Zhang, J., Guo, Y., Feng, B., Li, H., Lu, Y., Fang, X., Liang, H., Du, Z., Li, D., Zhao, Y., Hu, Y. & 57 others, Yang, Z., Zheng, H., Hellmann, I., Inouye, M., Pool, J., Yi, X., Zhao, J., Duan, J., Zhou, Y., Qin, J., Ma, L., Li, G., Yang, Z., Zhang, G., Yang, B., Yu, C., Liang, F., Li, W., Li, S., Li, D., Ni, P., Ruan, J., Li, Q., Zhu, H., Liu, D., Lu, Z., Li, N., Guo, G., Zhang, J., Ye, J., Fang, L., Hao, Q., Chen, Q., Liang, Y., Su, Y., San, A., Ping, C., Yang, S., Chen, F., Li, L., Zhou, K., Zheng, H., Ren, Y., Yang, L., Gao, Y., Yang, G., Li, Z., Feng, X., Kristiansen, Karsten, Wong, G. K., Nielsen, Rasmus, Durbin, R., Bolund, L., Zhang, X., Li, S., Yang, H. & Wang, J., 2008, In: Nature. 456, 7218, p. 60-65 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The power of inbreeding: NGS-based GWAS of rice reveals convergent evolution during rice domestication

    Wang, H., Xu, X., Vieira, Filipe Garrett, Xiao, Y., Li, Z., Wang, J., Nielsen, Rasmus & Chu, C., 6 Jul 2016, In: Molecular Plant. 9, 7, p. 975-985 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Synonymous mutations and the molecular evolution of SARS-CoV-2 origins

    Wang, H., Pipes, L. & Nielsen, Rasmus, 2021, In: Virus Evolution. 7, 1, 11 p., veaa098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. The discovery of Single-Nucleotide Polymorphisms: and Inferences about Human Demographic History

    Wakeley, J., Nielsen, Rasmus, Liu-Cordero, S. N. & Ardlie, K., 2001, In: American Journal of Human Genetics. 69, 6, p. 1332-1347 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Number of genes controlling a quantitative trait in a hybrid zone of the aposematic frog ranitomeya imitator

    Vestergaard, J. S., Twomey, E., Larsen, Rasmus Stenbak, Summers, K. & Nielsen, Rasmus, 22 May 2015, In: Proceedings of the Royal Society B: Biological Sciences. 282, 1807, 20141950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Massive haplotypes underlie ecotypic differentiation in sunflowers

    Todesco, M., Owens, G. L., Bercovich, N., Légaré, J. S., Soudi, S., Burge, D. O., Huang, K., Ostevik, K. L., Drummond, E. B. M., Imerovski, I., Lande, K., Pascual-Robles, M. A., Nanavati, M., Jahani, M., Cheung, W., Staton, S. E., Muños, S., Nielsen, R., Donovan, L. A., Burke, J. M. & 2 others, Yeaman, S. & Rieseberg, L. H., 2020, In: Nature. 584, 7822, p. 602-607 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Statistical assignment of DNA sequences using Bayesian phylogenetics

    Terkelsen, K. M., Boomsma, Wouter, Huelsenbeck, J. P., Willerslev, Eske & Nielsen, Rasmus, 2008, In: Systematic Biology. 57, 5, p. 750-757 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Fast phylogenetic DNA barcoding

    Terkelsen, K. M., Boomsma, Wouter, Willerslev, Eske & Nielsen, Rasmus, 2008, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 363, 1512, p. 3997-4002 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Inferring Adaptive Introgression Using Hidden Markov Models

    Svedberg, J., Shchur, V., Reinman, S., Nielsen, Rasmus & Corbett-Detig, R., 2021, In: Molecular Biology and Evolution. 38, 5, p. 2152-2165 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. The genomics of mimicry: Gene expression throughout development provides insights into convergent and divergent phenotypes in a Müllerian mimicry system

    Stuckert, A. M. M., Chouteau, M., McClure, M., LaPolice, T. M., Linderoth, T., Nielsen, Rasmus, Summers, K. & MacManes, M. D., 2021, In: Molecular Ecology. 30, 16, p. 4039-4061 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Costs and benefits of mutational robustness in RNA viruses

    Stern, A., Bianco, S., Yeh, M. T., Wright, C., Butcher, K., Tang, C., Nielsen, Rasmus & Andino, R., 2014, In: Cell Reports. 8, 4, p. 1026-1036 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies

    Stern, A. J., Speidel, L., Zaitlen, N. A. & Nielsen, Rasmus, 2021, In: American Journal of Human Genetics. 108, 2, p. 219-239 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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