Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor, emeritus

ORCID: 0000-0002-1085-8444

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  1. Published

    Pregabalin alleviates clinical signs of syringomyelia-related central neuropathic pain in Cavalier King Charles Spaniel dogs: a randomized controlled trial

    Thoefner, M. S., Skovgaard, Lene Theil, McEvoy, Fintan, Berendt, Mette & Bjerrum, Ole Jannik, 2020, In: Veterinary Anaesthesia and Analgesia. 47, 2, p. 238–248

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs

    Thoefner, M. S., Westrup, U., Toft, N., Bjerrum, Ole Jannik & Berendt, Mette, 2019, In: Veterinary Journal. 246, p. 92-97 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition

    Sawicki-Wrzask, D., Thomsen, M. & Bjerrum, Ole Jannik, 2015, In: Therapeutic Innovation & Regulatory Science. 49, 4, p. 553-559 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain

    Rode, F., Thomsen, M., Jensen, D. G., Blackburn-Munro, G., Bjerrum, Ole Jannik & Broløs, T., 2007, In: European Journal of Pharmacology. 564, 1-3, p. 103-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In: Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Sortilins in neuropathic pain

    Richner, M., Bjerrum, Ole Jannik, Koninck, Y. D., Nykjaer, A. & Vaegter, C. B., 29 Dec 2012, In: Scandinavian Journal of Pain. 3, 3, p. 183-184 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  7. Published

    Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

    Nøhr-Nielsen, A., Lange, Theis, Forman, Julie Lyng, Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2020, In: The AAPS Journal. 22, 2, 32.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

    Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, Theis, Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2019, In: British Journal of Clinical Pharmacology. 85, 8, p. 1829-1840 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Modification of beta-2-microglobulin in sera from patients with small cell lung cancer: evidence for involvement of a serine protease.

    Nissen, Mogens Holst, Bjerrum, Ole Jannik, Plesner, T., Wilken, M. & Rørth, M., 1987, In: Clinical and Experimental Immunology. 67, 2, p. 425-32 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A simple method for the preparation and purification of C1 complement cleaved beta 2-microglobulin from human serum.

    Nissen, Mogens Holst, Johansen, B. & Bjerrum, Ole Jannik, 1997, In: Journal of Immunological Methods. 205, 1, p. 29-33 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Smerteforskning, chilli con carne og floureserende stoffer

    Nielsen, C. K., Sheykhzade, Majid, Heegaard, Anne-Marie & Bjerrum, Ole Jannik, 2007, In: Lægemiddelforskning. p. 26-27

    Research output: Contribution to journal › Journal article › Communication

  12. Published

    Neuropathic pain: sortilin is involved in the down-regulation of KCC2

    Neustrup, S., P., M., Bjerregaard, C. V., Nykjær, A. & Bjerrum, Ole Jannik, 2010.

    Research output: Contribution to conference › Poster › Communication

  13. Published

    Intraplantar injection of tetrahydrobiopterin induces nociception in mice

    Nasser, A., Ali, S., Wilsbech, S., Bjerrum, Ole Jannik & Birk Møller, L., 2015, In: Neuroscience Letters. 584, p. 247-252 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The GTP-cyclohydrolase deficient mouse shows reduced acute pain perception

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie & Møller, L. B., 2010.

    Research output: Contribution to conference › Poster › Communication

  16. Published

    Genetik kan forudsige følsomhed for smerte

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie & Møller, L. B., 2010, In: Lægemiddelforskning. 2010, p. 34-36

    Research output: Contribution to journal › Journal article › Research

  17. Published

    Effect of GTP-cyclohydrolase deficiency in the HPH-1mouse on acute and inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik & Heegaard, Anne-Marie, 2010.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  18. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie, Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 Feb 2013, In: Molecular Pain. 9, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Dorsal horn volume loss and pain pathway changes in Cavalier King Charles Spaniels with syringomyelia, signs of pain, and phantom scratching

    Mortensen, D., Thoefner, M. S., Agerholm, Jørgen Steen, Slumstrup, L., Jensen, T. S., Bjerrum, Ole Jannik, Berendt, Mette & Nyengaard, J. R., 2022, In: Pain. 163, 12, p. 2365-2379

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In: European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, B., Oosterhuis, B., Bjerrum, Ole Jannik, Rowland, M. & Garner, C., 2010, In: European Journal of Pharmaceutical Sciences. 40, 2, p. 125-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

    Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, Anne-Marie & Bjerrum, Ole Jannik, Feb 2018, In: European Journal of Pain. 22, 2, p. 282-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development

    Krishna, R., Schaefer, H. G. & Bjerrum, Ole Jannik, 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 62-67

    Research output: Contribution to journal › Letter › Research

  25. Published

    The antinociceptive efficacy of buprenorphine administered through the drinking water of rats

    Jessen, L., Bjerrum, Ole Jannik & Christensen, S., 2007, In: Laboratory Animals. Journal of the Laboratory Animal Science Association. 41, 2, p. 185-96 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Neuropathic pain models in the development of analgesic drugs

    Honoré, P. G. H., Basnet, A., Eljaja, L., Kristensen, P., Neustrup, L. M., Møllgaard, P. & Bjerrum, Ole Jannik, 2011, In: Scandinavian Journal of Pain. 2, 4, p. 172-177 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Predictive validity of pharmacologic interventions in animal models of neuropathic pain

    Honoré, P. G. H., Basnet, A., Kristensen, P., Andersen, L. M., Neustrup, S., Møllgaard, P., Eljaja, L. & Bjerrum, Ole Jannik, 2011, In: Scandinavian Journal of Pain. 2, 4, p. 178-184 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Development of quantitative pharmacology-pharmacometrics in Denmark

    Honoré, P. G. H., Bjerrum, Ole Jannik, Lund, Trine Meldgaard, Angelo, H., Ingwersen, S. H., Thygesen, P., Kristensen, K. & Larsen, F., 2011.

    Research output: Contribution to conference › Poster › Research

  29. Published

    Quantitative Pharmacology – pharmacometrics: a vision for an educational programme in Denmark

    Honoré, P. G. H., Bjerrum, Ole Jannik, Ingwersen, S. H., Thygeson, P., Kristensen, K. & Larsen, F., 2010.

    Research output: Contribution to conference › Poster › Communication

  30. Published

    Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain

    Hald, A., Ding, M., Egerod, Kristoffer Lihme, Hansen, R. R., Konradsen, D., Jørgensen, S. G., Atalay, B., Nasser, A., Bjerrum, Ole Jannik & Heegaard, Anne-Marie, 2008, In: Pharmacology, Biochemistry and Behavior. 91, 1, p. 38-46 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and Pharmacology

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 225-253 29 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  32. Published

    Glutamate transport system as a key constituent of glutamosome: Molecular pathology and pharmacological modulation in chronic pain

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2019, In: Neuropharmacology. 161, 107623.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    High-affinity Glutamate Transporters in Pain: An Emerging and Therapeutic Target

    Gegelashvili, G. & Bjerrum, Ole Jannik, 2015, In: Journal of Neurochemistry. 6, p. 712-30 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The wider use of fixed-dose combinations emphasizes the need for a global approach to regulatory guideline development

    Gautam, Y., Bjerrum, Ole Jannik & Schmiegelow, M., 2015, In: Therapeutic Innovation & Regulatory Science. 49, 1, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Co-administered gabapentin and venlafaxine in nerve injured rats: effect on mechanical hypersensitivity, motor function and pharmacokinetics

    Folkesson, A. J. M., Honoré, P. G. H. & Bjerrum, Ole Jannik, 2009, In: Scandinavian Journal of Pain. 1, 2, p. 91-97

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Low dose of donepezil improves gabapentin analgesia in the rat spared nerve injury model of neuropathic pain: single and multiple dosing studies

    Folkesson, A., Honoré, P. H., Andersen, L. M., Kristensen, P. J. & Bjerrum, Ole Jannik, 2010, In: Journal of Neural Transmission. 117, p. 1377-1385

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effects of the excitatory amino acid transporter subtype 2(EAAT-2) inducer ceftriaxone on different pain modalities in rat

    Eljaja, L., Bjerrum, Ole Jannik, Honoré, P. G. H. & Abrahamsen, B., 2011, In: Scandinavian Journal of Pain. 2, 3, p. 132-136 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The EUFEPS workshop on institutional peer review "The ultimate tool to advance the pharmaceutical sciences?" A continuing story: A continuing story

    Crommelin, D. J. A. & Bjerrum, Ole Jannik, 2008, In: European Journal of Pharmaceutical Sciences. 35, 4, p. 361-364

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Pharmacy student driven detection of adverse drug reactions in the community pharmacy setting

    Christensen, S. T., Søndergaard, B., Honoré, P. H. & Bjerrum, Ole Jannik, 2011, In: Pharmacoepidemiology and Drug Safety. 20, p. 399-404 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Fast detection of adverse drug reactions of new drugs by community pharmacists

    Christensen, S. T. & Bjerrum, Ole Jannik, 2010, In: Drug Safety. 33, 10, p. 928

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Bivirkningsmonitorering af lægemidler: en ny udfordring af apoteksfarmaceuter

    Christensen, S. T. & Bjerrum, Ole Jannik, 2009, In: Lægemiddelforskning. p. 49-51

    Research output: Contribution to journal › Journal article › Communication

  42. Published

    Blå medicin mod smerter

    Boulakou, A., Bjerrum, Ole Jannik & Honoré, P. G. H., 2012, In: Lægemiddelforskning. 2012, p. 18-19 2 p.

    Research output: Contribution to journal › Journal article › Communication

  43. Published

    A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science: Workshop Proceedings and Commentary

    Borup, G., Bach, K. F., Schmiegelow, M., Kildemoes, H. W., Bjerrum, Ole Jannik & Westergaard, N., May 2016, In: Therapeutic Innovation & Regulatory Science. 50, 3, p. 304-311 8 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  44. Published

    Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine

    Bjerrum, Ole Jannik & Androlyte, M., Aug 2018, In: Basic & Clinical Pharmacology & Toxicology. 123 , 2, p. 155–160 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    A novel inhibitor of advanced glycation end- product formation inhibits mesenteric vascular hypertrophy in experimental diabetes

    Bjerrum, Ole Jannik, 1999, In: Diabetologica. 42, p. 472-479 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    New Safe Medicines Faster. A proposition for a pan-European research effort

    Bjerrum, Ole Jannik, May 2002, In: Nature Reviews. Drug Discovery. 1, 5, p. 395-398 4 p.

    Research output: Contribution to journal › Journal article › Communication

  47. Published

    Beta-lactam antibiotic as dose dependent analgesic treatment of neuropathic pain

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., 2011.

    Research output: Contribution to conference › Poster › Research › peer-review

  48. Published

    Why medicines Combinations? Friend or Foe?

    Bjerrum, Ole Jannik, Gautam, Y., Boonen, H. C. M., Schmiegelow, M. & Honoré, P. G. H., 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  49. Published

    Venlafaxine compromises the antinoceptive actions of gabapentin in rat models of neuropathic and persistent pain

    Bjerrum, Ole Jannik, 2006, In: Psychopharmacology. 187, p. 364-375 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Community pharmacy driven pharmacovigilance

    Bjerrum, Ole Jannik & Christensen, S. T., 2010.

    Research output: Contribution to conference › Poster › Communication

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