Michael Kjær

Michael Kjær

Clinical Professor

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  1. 2024
  2. Published

    Lower basal and postprandial muscle protein synthesis after 2 weeks single-leg immobilization in older men: No protective effect of anti-inflammatory medication

    Dideriksen, K., Reitelseder, S., Boesen, A. P., Zillmer, M., Agergaard, J., Kjær, Michael & Holm, L., 2024, In: Physiological Reports. 12, 4, 13 p., e15958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Marked irregular myofiber shape is a hallmark of human skeletal muscle ageing and is reversed by heavy resistance training

    Soendenbroe, C., Karlsen, Anders, Svensson, R. B., Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2024, In: Journal of Cachexia, Sarcopenia and Muscle. 15, 1, p. 306-318 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort

    Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, Hansen, Torben, Linneberg, Allan René & Vaag, Allan, 2024, In: BMJ Open. 14, 1, 10 p., e078501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Tendon Elongation and Function After Delayed or Standard Loading of Surgically Repaired Achilles Tendon Ruptures: A Randomized Controlled Trial

    Høffner, Rikke, Agergaard, Anne-Sofie, Svensson, R. B., Cullum, C., Mikkelsen, R. K., Konradsen, L., Krogsgaard, Michael R., Boesen, Mikael Ploug, Kjær, Michael & Magnusson, Stig Peter, 2024, In: American Journal of Sports Medicine. 52, 4, p. 1022-1031 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    Fusion of myofibre branches is a physiological feature of healthy human skeletal muscle regeneration

    Højfeldt, Grith Stougaard, Sorenson, T., Gonzales, A., Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 12 Aug 2023, In: Skeletal Muscle. 13, 1, p. 1-14 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Achilles Tendon Tissue Turnover Before and Immediately After an Acute Rupture

    Cramer, A., Højfeldt, Grith Stougaard, Schjerling, Peter, Agergaard, J., van Hall, Gerrit, Olsen, J., Hölmich, Per, Kjær, Michael & Barfod, Kristoffer Weisskirchner, 2023, In: American Journal of Sports Medicine. 51, 9, 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Acute loading has minor influence on human articular cartilage gene expression and glycosaminoglycan composition in late-stage knee osteoarthritis: a randomised controlled trial

    Jørgensen, A. E. M., Schjerling, Peter, DellaValle, B., Rungby, Jørgen & Kjær, Michael, 2023, In: Osteoarthritis and Cartilage. 31, 7, p. 884-893 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts

    Demnitz, N., Hulme, Oliver James, Siebner, Hartwig Roman, Kjær, Michael, Ebmeier, K. P., Boraxbekk, CJ & Gillan, C. M., 2023, In: Neurobiology of Aging. 131, p. 115-123

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Chronic changes in muscle architecture and aponeurosis structure following calf muscle strain injuries

    B. Nielsen, L., B. Svensson, R., U. Fredskild, N., H. Mertz, K., Magnusson, Stig Peter, Kjær, Michael & Bayer, M. L., 2023, In: Scandinavian Journal of Medicine and Science in Sports. 33, 12, p. 2585-2597 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Differences in the cross-sectional area along the ankle tendons with both age and sex

    Mansur, H., Durigan, J. L. Q., de Noronha, M., Kjær, Michael, Magnusson, Stig Peter, de Araújo, B. A. S. & de Cássia Marqueti, R., 2023, In: Journal of Anatomy. 242, 2, p. 213-223

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. E-pub ahead of print

    Disruption of day-to-night changes in circadian gene expression with chronic tendinopathy

    Yeung, Ching-Yan Chloé, Svensson, R. B., Yurchenko, K., Malmgaard-Clausen, N. M., Tryggedsson, I., Lendal, M., Jokipii-Utzon, A., Olesen, J. L., Lu, Y., Kadler, K. E., Schjerling, Peter & Kjær, Michael, 2023, (E-pub ahead of print) In: Journal of Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Distinct myofibre domains of the human myotendinous junction revealed by single-nucleus RNA sequencing

    Karlsen, Anders, Yeung, Ching-Yan Chloé, Schjerling, Peter, Denz, L., Høgsbjerg, Christian, Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Schiaffino, S., Kjær, Michael & Mackey, Abigail, 2023, In: Journal of Cell Science. 136, 8, 14 p., jcs260913.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (1H-MRS) in humans: A systematic review

    Ryberg, M., Boraxbekk, CJ, Kjær, Michael & Demnitz, N., 2023, In: Heliyon. 9, 10, 13 p., e20534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults

    Demnitz, N., Gates, A. T., Mortensen, Erik Lykke, Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Siebner, Hartwig Roman, Kjær, Michael & Boraxbekk, CJ, 2023, In: Human Brain Mapping. 44, 11, p. 4299-4309 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Larger interface area at the human myotendinous junction in type 1 compared to type 2 muscle fibers

    Rithamer Jakobsen, J., Mackey, Abigail, Koch, M., Imhof, T., Hannibal, Jens, Kjær, Michael & Rindom Krogsgaard, M., 2023, In: Scandinavian Journal of Medicine & Science in Sports. 33, 2, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model

    Høffner, Rikke, Svensson, R. B., Dietrich-Zagonel, F., Schefte, D., Kjær, Michael, Eliasson, P. & Magnusson, Stig Peter, 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 135, 2, p. 326-333 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Proteome profiles of intramuscular connective tissue: influence of aging and physical training

    Yeung, Ching-Yan Chloé, Olesen, A. T., Wilson, R., Lamandé, S. R., Bateman, J. F., Svensson, R. B., Magnusson, Stig Peter & Kjær, Michael, 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 134, 5, p. 1278-1286 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Tendon properties in a mouse model of severe osteogenesis imperfecta

    Sinkam, L., Boraschi-Diaz, I., Svensson, R. B., Kjær, Michael, Komarova, S. V., Bergeron, R., Rauch, F. & Veilleux, L. N., 2023, In: Connective Tissue Research. 64, 3, p. 285-293

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Tensile Loaded Tissue-Engineered Human Tendon Constructs Stimulate Myotube Formation

    Tsuchiya, Y., Svensson, R. B., Yeung, Ching-Yan Chloé, Schjerling, Peter & Kjær, Michael, 2023, In: Tissue Engineering - Part A. 29, 9-10, p. 292-305 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2022
  23. Published

    Intramuscular connective tissue content and mechanical properties: Influence of aging and physical activity in mice

    Olesen, A. T., Malchow-møller, L., Bendixen, R. D., Kjær, Michael, Mackey, Abigail, Magnusson, Stig Peter & Svensson, R. B., 1 Jul 2022, In: Experimental Gerontology. p. 111893

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Editorial: Trends in Muscle and Tendon Molecular and Cell Biology

    Marqueti, R. D. C., Kjær, Michael & Moriscot, A. S., 3 Feb 2022, In: Frontiers in Physiology. 12, 3 p., 832613.

    Research output: Contribution to journal › Editorial › Research › peer-review

  25. Published

    Autophagy guards tendon homeostasis

    Montagna, C., Svensson, R. B., Bayer, M. L., Rizza, S., Maiani, E., Yeung, Ching-Yan Chloé, Filomeni, G. & Kjær, Michael, 2022, In: Cell Death and Disease. 13, 4, 402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Circadian regulation of protein cargo in extracellular vesicles

    Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effect of Ultrasonography-Guided Corticosteroid Injection vs Placebo Added to Exercise Therapy for Achilles Tendinopathy: A Randomized Clinical Trial

    Johannsen, F., Olesen, J. L., Øhlenschläger, T. F., Lundgaard-Nielsen, M., Cullum, C. K., Jakobsen, A. S., Rathleff, M. S., Magnusson, Stig Peter & Kjær, Michael, 2022, In: JAMA network open. 5, 7, 14 p., E2219661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Effects of Heavy Slow Resistance Training Combined With Corticosteroid Injections or Tendon Needling in Patients With Lateral Elbow Tendinopathy A 3-Arm Randomized Double-Blinded Placebo-Controlled Study

    Couppé, Christian, Døssing, S., Bulow, P. M., Siersma, Volkert Dirk, Zilmer, C. K., Bang, C. W., Høffner, Rikke, Kracht, M., Hogg, P., Edstrom, G., Kjær, Michael & Magnusson, Stig Peter, 2022, In: American Journal of Sports Medicine. 50, 10, p. 2787-2796 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effects of age on muscle power, postural control and functional capacity after short-term immobilization and retraining

    Elam, C., Hvid, L. G., Christensen, U., Kjær, Michael, Magnusson, Stig Peter, Aagaard, P., Bunketorp Käll, L. & Suetta, Charlotte, 2022, In: Journal of Musculoskeletal Neuronal Interactions. 22, 4, p. 486-497 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Exercise in patients with hip osteoarthritis - effects on muscle and functional performance: A randomized trial

    Bieler, T., Kristensen, A. L. R., Nyberg, M., Magnusson, Stig Peter, Kjær, Michael & Beyer, N., 2022, In: Physiotherapy Theory and Practice. 38, 12, p. 1946-1957

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Human skeletal muscle acetylcholine receptor gene expression in elderly males performing heavy resistance exercise

    Soendenbroe, C., Flindt Heisterberg, M. F., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: American journal of physiology. Cell physiology. 323, p. C159–C169

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Meeting Report: Aging Research and Drug Discovery

    Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, Freund, A., Georgievskaya, A., Gladyshev, V. N., Glass, D., Golato, T., Gorbunova, V., Hoejimakers, J., Houtkooper, R. H., Jager, S., Jaksch, F., Janssens, G., Jensen, M. B., Kaeberlein, M., Karsenty, G., de Keizer, P., Kennedy, B., Kirkland, J. L., Kjær, Michael, Kroemer, G., Lee, K. F., Lemaitre, J. M., Liaskos, D., Longo, V. D., Lu, Y. X., MacArthur, M. R., Maier, A. B., Manakanatas, C., Mitchell, S. J., Moskalev, A., Niedernhofer, L., Ozerov, I., Partridge, L., Passegué, E., Petr, Michael Angelo, Peyer, J., Radenkovic, D., Rando, T. A., Rattan, S., Riedel, C. G., Rudolph, L., Ai, R., Serrano, M., Schumacher, B., Sinclair, D. A., Smith, R., Suh, Y., Taub, P., Trapp, A., Trendelenburg, A. U., Valenzano, D. R., Verburgh, K., Verdin, E., Vijg, J., Westendorp, Rudi GJ, Zonari, A., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Aging. 14, 2, p. 530-543 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Nestin and osteocrin mRNA increases in human semitendinosus myotendinous junction 7 days after a single bout of eccentric exercise

    Jakobsen, J. R., Schjerling, Peter, Kjær, Michael, Mackey, Abigail & Krogsgaard, Michael R., 2022, In: Histochemistry and Cell Biology. 158, p. 49–64

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Pathological Tendon Histology in Early and Chronic Human Patellar Tendinopathy

    Malmgaard-Clausen, N. M., Kjær, Michael & Dakin, S. G., 2022, In: Translational Sports Medicine. 2022, 2799665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Persistent Deficits after an Achilles Tendon Rupture: A Narrative Review

    Høffner, Rikke, Svensson, R. B., Bjerregaard, N., Kjær, Michael & Magnusson, Stig Peter, 2022, In: Translational Sports Medicine. 2022

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

    Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The proteomic profile of the human myotendinous junction

    Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis

    Jørgensen, A. E. M., Agergaard, J., Schjerling, Peter, Heinemeier, K. M., van Hall, Gerrit & Kjær, Michael, 2022, In: Osteoarthritis and Cartilage. 30, 6, p. 886-895

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2021
  41. Published

    Different training responses in elderly men and women following a prolonged muscle resistance training intervention

    Gates, A. T., Mertz, K. H., Bloch-Ibenfeldt, Mads, Garde, Ellen, Baekgaard, M., Svensson, René Brüggebusch & Kjær, Michael, 1 Nov 2021, In: Translational Sports Medicine. 4, 6, p. 892-899 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

    Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, Treebak, Jonas Thue, 2021, In: Molecular Metabolism. 53, 101271.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Adipocytes are present at human and murine myotendinous junctions

    Jakobsen, J. R., Jakobsen, N. R., Mackey, Abigail, Knudsen, A. B., Hannibal, Jens, Koch, M., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Translational Sports Medicine. 4, 2, p. 223-230

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running

    Olesen, A. T., Alchow-Moller, L., Bendixen, R. D., Kjær, Michael, Svensson, R. B., Andersen, J. L. & Magnusson, Stig Peter, 2021, In: Experimental Gerontology. 143, 111150.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial

    Bayer, M. L., Hoegberget-Kalisz, M., Svensson, R. B., Hjortshoej, M. H., Olesen, J. L., Nybing, J. D., Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2021, In: American Journal of Sports Medicine. 49, 10, p. 2783-2794 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Chronic hyperglycemia, hypercholesterolemia, and metabolic syndrome are associated with risk of tendon injury

    Skovgaard, D., Siersma, Volkert Dirk, Klausen, S. B., Visnes, H., Haukenes, I., Bang, C. W., Bager, P., Gravare Silbernagel, K., Gaida, J., Magnusson, Stig Peter, Kjær, Michael & Couppé, Christian, 2021, In: Scandinavian Journal of Medicine & Science in Sports. 31, 9, p. 1822-1831 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Clinical Outcomes, Structure, and Function Improve With Both Heavy and Moderate Loads in the Treatment of Patellar Tendinopathy: A Randomized Clinical Trial

    Agergaard, Anne-Sofie, Svensson, R. B., Malmgaard-Clausen, N. M., Couppé, Christian, Hjortshoej, M. H., Doessing, S., Kjær, Michael & Magnusson, Stig Peter, 2021, In: American Journal of Sports Medicine. 49, 4, p. 982-993 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Collagen Growth Pattern in Human Articular Cartilage of the Knee

    Jørgensen, A. E. M., Schjerling, Peter, Krogsgaard, Michael R., Petersen, Michael Mørk, Olsen, J., Kjær, Michael & Heinemeier, K. M., 2021, In: Cartilage. 13, Suppl. 2, p. 408S-418S

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Collagens in primary frozen shoulder: expression of collagen mRNA isoforms in the different phases of the disease

    Marker, L., Schjerling, P., Mackey, Abigail, Hansen, T., Jakobsen, J., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Rheumatology. 60, 8, p. 3879-3887

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Effects of genipin crosslinking on mechanical cell-matrix interaction in 3D engineered tendon constructs

    Giannopoulos, A., Svensson, R. B., Yeung, Ching-Yan Chloé, Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of the Mechanical Behavior of Biomedical Materials. 119, 104508.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Habitual side-specific loading leads to structural, mechanical, and compositional changes in the patellar tendon of young and senior lifelong male athletes

    Couppé, Christian, Svensson, R. B., Skovlund, S. V., Jensen, Jacob Kildevang, Eriksen, C. S., Malmgaard-Clausen, N. M., Nybing, J. D., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of Applied Physiology. 131, 4, p. 1187-1199

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins?

    Agergaard, J. & Kjær, Michael, 2021, In: Function. 2, 4, 2 p., 034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Magnetic Resonance T-2* Is Increased in Patients With Early-Stage Achilles and Patellar Tendinopathy

    Malmgaard-Clausen, N. M., Tran, P., Svensson, R. B., Hansen, Philip, Nybing, J. D., Magnusson, Stig Peter & Kjær, Michael, 2021, In: Journal of Magnetic Resonance Imaging. 54, 3, p. 832-839

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Mechanical properties and UTE-T2* in Patellar tendinopathy: The effect of load magnitude in exercise-based treatment

    Agergaard, A. S., Svensson, R. B., Høffner, Rikke, Hansen, P., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 10, p. 1981-1990

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 13775