Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. 2021
  2. Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer

    Wiebringhaus, R., Pecoraro, M., Neubauer, H. A., Trachtová, K., Trimmel, B., Wieselberg, M., Pencik, J., Egger, G., Krall, C., Moriggl, R., Mann, Matthias, Hantusch, B. & Kenner, L., 30 Nov 2021, In: Cancers. 13, 23

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex

    Haider, N., Lebastchi, J., Jayavelu, A. K., Batista, T. M., Pan, H., Dreyfuss, J. M., Carcamo-Orive, I., Knowles, J. W., Mann, Matthias & Kahn, C. R., 1 Nov 2021, In: The Journal of Clinical Investigation. 131, 21

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling

    Tanzer, M. C., Bludau, I., Stafford, C. A., Hornung, V. & Mann, Matthias, 18 Oct 2021, In: Nature Communications. 12, 1, p. 6053

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

    Hoefig, K. P., Reim, A., Gallus, C., Wong, E. H., Behrens, G., Conrad, C., Xu, M., Kifinger, L., Ito-Kureha, T., Defourny, K. A. Y., Geerlof, A., Mautner, J., Hauck, S. M., Baumjohann, D., Feederle, R., Mann, Matthias, Wierer, M., Glasmacher, E. & Heissmeyer, V., 1 Sep 2021, In: Nature Communications. 12, 1, p. 5208

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Artificial intelligence for proteomics and biomarker discovery

    Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics

    Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Identification of the transcription factor MAZ as a regulator of erythropoiesis

    Deen, D., Butter, F., Daniels, D. E., Ferrer-Vicens, I., Ferguson, D. C. J., Holland, M. L., Samara, V., Sloane-Stanley, J. A., Ayyub, H., Mann, Matthias, Frayne, J., Garrick, D. & Vernimmen, D., 10 Aug 2021, In: Blood advances. 5, 15, p. 3002-3015 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Identification of covalent modifications regulating immune signaling complex composition and phenotype

    Frauenstein, A., Ebner, S., Hansen, F. M., Sinha, A., Phulphagar, K., Swatek, K., Hornburg, D., Mann, Matthias & Meissner, F., Jul 2021, In: Molecular Systems Biology. 17, 7, p. e10125

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

    Wigger, L., Barovic, M., Brunner, A-D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., Simons, K. & 7 others, Aust, D., Weitz, J., Distler, M., Schulte, A. M., Mann, Matthias, Ibberson, M. & Solimena, M., 28 Jun 2021, (E-pub ahead of print) In: Nature Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme

    Sherpa, D., Chrustowicz, J., Qiao, S., Langlois, C. R., Hehl, L. A., Gottemukkala, K. V., Hansen, F. M., Karayel, O., von Gronau, S., Prabu, J. R., Mann, Matthias, Alpi, A. F. & Schulman, B. A., 22 Apr 2021, (E-pub ahead of print) In: Molecular Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

    Tain, L. S., Sehlke, R., Meilenbrock, R. L., Leech, T., Paulitz, J., Chokkalingam, M., Nagaraj, N., Grönke, S., Fröhlich, J., Atanassov, I., Mann, Matthias, Beyer, A. & Partridge, L., 21 Apr 2021, In: eLife. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

    Stukalov, A., Girault, V., Grass, V., Karayel, O., Bergant, V., Urban, C., Haas, D. A., Huang, Y., Oubraham, L., Wang, A., Hamad, M. S., Piras, A., Hansen, F. M., Tanzer, M. C., Paron, I., Zinzula, L., Engleitner, T., Reinecke, M., Lavacca, T. M., Ehmann, R. & 10 others, Wölfel, R., Jores, J., Kuster, B., Protzer, U., Rad, R., Ziebuhr, J., Thiel, V., Scaturro, P., Mann, Matthias & Pichlmair, A., 12 Apr 2021, (E-pub ahead of print) In: Nature.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

    Wierer, M., Werner, J., Wobst, J., Kastrati, A., Cepele, G., Aherrahrou, R., Sager, H. B., Erdmann, J., Dichgans, M., Flockerzi, V., Civelek, M., Dietrich, A., Mann, Matthias, Schunkert, H. & Kessler, T., 8 Apr 2021, (E-pub ahead of print) In: European Heart Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway

    Takahashi, M., Lio, C. J., Campeau, A., Steger, M., Ay, F., Mann, Matthias, Gonzalez, D. J., Jain, M. & Sharma, S., Apr 2021, In: Nature Immunology. 22, 4, p. 485-496 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

    Liwocha, J., Krist, D. T., van der Heden van Noort, G. J., Hansen, F. M., Truong, V. H., Karayel, O., Purser, N., Houston, D., Burton, N., Bostock, M. J., Sattler, M., Mann, Matthias, Harrison, J. S., Kleiger, G., Ovaa, H. & Schulman, B. A., Mar 2021, In: Nature Chemical Biology. 17, 3, p. 272-279 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions

    Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology

    Hansen, F. M., Tanzer, M. C., Brüning, F., Bludau, I., Stafford, C., Schulman, B. A., Robles, M. S., Karayel, O. & Mann, Matthias, 11 Jan 2021, In: Nature Communications. 12, 1, p. 254

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

    Kaya-Çopur, A., Marchiano, F., Hein, M. Y., Alpern, D., Russeil, J., Luis, N. M., Mann, Matthias, Deplancke, B., Habermann, B. H. & Schnorrer, F., 6 Jan 2021, In: eLife. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

    Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. AlphaTims: Indexing Trapped Ion Mobility Spectrometry-TOF Data for Fast and Easy Accession and Visualization

    Willems, S., Voytik, E., Skowronek, P., Strauss, Maximilian & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, p. 100149

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity

    Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Deep learning the collisional cross sections of the peptide universe from a million experimental values

    Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Defining NASH from a multi-omics systems biology perspective

    Niu, Lili, Sulek, K., Vasilopoulou, C. G., Santos, A., Albrechtsen, Nicolai Jacob Wewer, Rasmussen, Simon, Meier, F. & Mann, Matthias, 2021, In: Journal of Clinical Medicine. 10, 20, 22 p., 4673.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

    Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.

    Research output: Contribution to journalJournal articleResearchpeer-review

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