Mads Gyrd-Hansen

Mads Gyrd-Hansen

Professor


  1. 2008
  2. Published

    IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

    Gyrd-Hansen, Mads, Darding, M., Miasari, M., Santoro, M. M., Zender, L., Xue, W., Tenev, T., da Fonseca, P. C. A., Zvelebil, M., Bujnicki, J. M., Lowe, S., Silke, J. & Meier, P., 2008, In: Nature Cell Biology. 10, 11, p. 1309-17 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lysosomes and Nonapoptotic Pathways

    Kirkegaard-Sørensen, T., Fehrenbacher, N., Gyrd-Hansen, Mads & Jüüttelü, M., 26 May 2008, Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts. John Wiley and Sons, Inc., Vol. 1. p. 599-622 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. 2010
  5. Published

    IAPs: From caspase inhibitors to modulators of NF-κB, inflammation and cancer

    Gyrd-Hansen, Mads & Meier, P., 2010, In: Nature Reviews Cancer.

    Research output: Contribution to journalJournal articleCommissionedpeer-review

  6. Published

    IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

    Gyrd-Hansen, Mads & Meier, P., 2010, In: Nature Reviews. Cancer. 10, 8, p. 561-74 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. 2011
  8. Published

    Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity

    Damgaard, R. B. & Gyrd-Hansen, Mads, 2011, In: Discovery Medicine. 11, 58, p. 221-31 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. 2012
  10. Published

    The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

    Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2013
  12. Published

    OTULIN antagonizes LUBAC signaling by specifically hydrolyzing met1-linked polyubiquitin

    Keusekotten, K., Elliott, P. R., Kulathu, Y., Wauer, T., Hospenthal, M. K., Komander, D., Glockner, L., Krappmann, D., Fiil, Berthe Katrine, Damgaard, R. B., Gyrd-Hansen, Mads & Hofmann, K., 6 Jun 2013, In: Cell. 153, 6, p. 1312-1326 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

    Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In: Molecular Cell. 50, 6, p. 818-30 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    X-linked inhibitor of apoptosis (XIAP) deficiency: The spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis

    Speckmann, C., Lehmberg, K., Albert, M. H., Damgaard, R. B., Fritsch, M., Gyrd-Hansen, M., Rensing-Ehl, A., Vraetz, T., Grimbacher, B., Salzer, U., Fuchs, I., Ufheil, H., Belohradsky, B. H., Hassan, A., Cale, C. M., Elawad, M., Strahm, B., Schibli, S., Lauten, M., Kohl, M. & 10 others, Meerpohl, J. J., Rodeck, B., Kolb, R., Eberl, W., Soerensen, J., von Bernuth, H., Lorenz, M., Schwarz, K., zur Stadt, U. & Ehl, S., 1 Oct 2013, In: Clinical Immunology. 149, 1, p. 133-141 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4000197