Kristian Strømgaard

Kristian Strømgaard

Professor

ORCID: 0000-0003-2206-4737

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  1. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata

    Barslund, A. F., Poulsen, Mette Homann, Bach, T. B., Lucas, S., Kristensen, Anders Skov & Strømgaard, Kristian, 2011, In: Journal of Natural Products. 74, 3, p. 483-486

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms

    Bleem, A., Christiansen, G., Madsen, D. J., Maric, H., Strømgaard, Kristian, Bryers, J. D., Daggett, V., Meyer, R. L. & Otzen, D. E., 2018, In: Journal of Molecular Biology. 430, 20, p. 3751-3763 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Stoichiometry of Toxin Binding to Acid-Sensing Ion Channels

    Borg, C. B., Lynagh, T., Haugaard-Kedstrom, L. M., Strømgaard, Kristian & Pless, Stephan, 3 Feb 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 420A-420A

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  6. Published

    Peptide Modulation of Acid-Sensing Ion Channels

    Borg, C. B., Haugaard-Kedstrom, L. M., Lynagh, T., Strømgaard, Kristian & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conference › Poster › Research

  7. Published

    Prevention of glutamate-induced retinal ganglion cell death by UCCB01-144 treatment

    Bulli, G., Vohra, Rupali, Skytt, D. M., Strømgaard, Kristian & Kolko, Miriam, 2018, In: Acta Ophthalmologica. 96, S261, p. 17-17 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  8. Published

    Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

    Cheng, J., Sahani, S., Hausrat, T. J., Yang, J-W., Ji, H., Schmarowski, N., Endle, H., Liu, X., Li, Y., Böttche, R., Radyushkin, K., Maric, H. M., Hoerder-Suabedissen, A., Molnár, Z., Prouvot, P-H., Trimbuch, T., Ninnemann, O., Huai, J., Fan, W., Visentin, B. & 7 others, Sabbadini, R., Strømgaard, Kristian, Stroh, A., Luhmann, H. J., Kneussel, M., Nitsch, R. & Vogt, J., 5 Oct 2016, In: Neuron. 92, 1, p. 126-142 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A sequential binding mechanism in a PDZ domain

    Chi, C. N., Bach, Anders, Engström, Å., Wang, H., Strømgaard, Kristian, Gianni, S. & Jemth, P., 2009, In: Biochemistry. 48, 30, p. 7089-7097

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Ligand binding by PDZ domains

    Chi, C. N., Bach, Anders, Strømgaard, Kristian, Gianni, S. & Jemth, P., 2012, In: BioFactors. 38, 5, p. 338-348 (Review) 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97

    Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3597-3606

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    PDZ Domains as Drug Targets

    Christensen, N. R., Čalyševa, J., Alves Fernandes, Eduardo Felipe, Lüchow, S., Clemmensen, L. S., Haugaard-Kedström, L. M. & Strømgaard, Kristian, 2019, In: Advanced Therapeutics. 2, 7, p. 1800143 1800143.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations

    Eildal, J. N. N., Hultqvist, G., Balle, T., Stuhr-Hansen, N., Padrah, S., Gianni, S., Strømgaard, Kristian & Jemth, P., 4 Sep 2013, In: Journal of the American Chemical Society. 135, 35, p. 12998-3007 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    Eildal, J. N. N., Bach, Anders, Dogan, J., Ye, F., Zhang, M., Jemth, P. & Strømgaard, Kristian, 2015, In: ChemBioChem. 16, p. 64–69 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

    Fiorentini, M., Bach, Anders, Strømgaard, Kristian, Kastrup, Jette Sandholm Jensen & Gajhede, Michael, Apr 2013, In: Acta Crystallographica. Section D: Biological Crystallography. 69, Pt 4, p. 587-94 8 p.

    Research output: Contribution to journal › Journal article › Research

  17. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

    Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

    Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Neurochemical Research. 34, 10, p. 1729-1737

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains

    Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In: Journal of the American Chemical Society. 134, 1, p. 599-605

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS

    Haugaard-Kedstrom, L. M., Albertsen, L., Gil, F. A., Ivarsson, Y., Strømgaard, Kristian & Kedström, L. M. H., Sep 2014, In: Journal of Peptide Science. 20, Suppl. 1, p. s39 1 p., YO11.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  21. Published

    Targeting PSD-95 as a Novel Approach in the Treatment of Stroke

    Haugaard-Kedstrom, L. M., Fernandes, E. F. A. & Strømgaard, Kristian, 2017, Neuroprotective Therapy for Stroke and Ischemic Disease . Springer, p. 157-184 28 p. (Springer Series in Translational Stroke Research).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Energetic pathway sampling in a protein interaction domain

    Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In: Structure. 21, 7, p. 1193-1202

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    An expanded view of the protein folding landscape of PDZ domains

    Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In: Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease

    Jensen, T. M. T., Albertsen, L., Bartling, Christian Reinhard Otto, Haugaard-kedström, L. M. & Strømgaard, Kristian, 2018, In: ChemBioChem. 19, 11, p. 1119-1122 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

    Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

    Research output: Contribution to journal › Journal article › Research

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ID: 1302559