Kristian Strømgaard

Kristian Strømgaard

Professor

ORCID: 0000-0003-2206-4737

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  1. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain

    Thorsen, T. S., Madsen, Kenneth Lindegaard, Dyhring, T., Bach, Anders, Peters, D., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 1 Aug 2011, In: Combinatorial Chemistry & High Throughput Screening. 14, 7, p. 590-600 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A heteromeric snake toxin and the molecular details of pain perception

    Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In: Angewandte Chemie International Edition. 51, 17, p. 4009-4011

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY

    Albertsen, L., Østergaard, S., Paulsson, J. F., Norrild, J. C. & Strømgaard, Kristian, Sep 2013, In: ChemMedChem. 8, 9, p. 1505-13

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A sequential binding mechanism in a PDZ domain

    Chi, C. N., Bach, Anders, Engström, Å., Wang, H., Strømgaard, Kristian, Gianni, S. & Jemth, P., 2009, In: Biochemistry. 48, 30, p. 7089-7097

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins

    Strømgaard, Kristian & Mellor, I., Sep 2004, In: Medicinal Research Reviews. 24, 5, p. 589-620 32 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    An expanded view of the protein folding landscape of PDZ domains

    Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In: Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Antidepressive lægemidler: nu i 3D

    Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In: Lægemiddelforskning. 2010, p. 25-27

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

    Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Binding of ArgTX-636 in the NMDA receptor ion channel

    Poulsen, M. H., Andersen, J., Christensen, R., Hansen, K. B., Traynelis, S. F., Strømgaard, Kristian & Kristensen, Anders Skov, 16 Jan 2015, In: Journal of Molecular Biology. 427, 1, p. 176-89 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter

    Andersen, J., Ladefoged, L. K., Wang, D., Kristensen, T. N. B., Bang-Andersen, B., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 18 Nov 2015, In: A C S Chemical Neuroscience. 6, 11, p. 1892-900 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

    Andersen, J., Ringsted, K. B., Bang-Andersen, B., Strømgaard, Kristian & Kristensen, Anders Skov, 2015, In: Scientific Reports. 5, p. 1-12 12 p., 15650.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97

    Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3597-3606

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites

    Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, 18 Apr 2014, In: ACS chemical biology. 9, 4, p. 935-44 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Chemical biology

    Strømgaard, Kristian, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 59-74

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  17. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba

    Strømgaard, Kristian & Nakanishi, K., 19 Mar 2004, In: Angewandte Chemie International Edition. 43, 13, p. 1640-1658 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors

    Brier, T. J., Mellor, I. R., Tikhonov, D. B., Neagoe, I., Shao, Z., Brierley, M. J., Strømgaard, Kristian, Jaroszewski, J. W., Krogsgaard-Larsen, Povl & Usherwood, P. N. R., Oct 2003, In: Molecular Pharmacology. 64, 4, p. 954-964 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors

    Maric, H., Kasaragod, V. B., Kedström, L. M. H., Hausrat, T. J., Kneussel, M., Schindelin, H. & Strømgaard, Kristian, 7 Jan 2015, In: Angewandte Chemie (International ed. in English). 54, 2, p. 490-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

    Andersen, T. F., Vogensen, S. B., Jensen, L. S., Knapp, K. M. & Strømgaard, Kristian, 1 Sep 2005, In: Bioorganic & Medicinal Chemistry. 13, 17, p. 5104-5112 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications

    Albertsen, L., Andersen, J. J., Paulsson, J. F., Thomsen, J. K., Norrild, J. C. & Strømgaard, Kristian, 12 Dec 2013, In: A C S Medicinal Chemistry Letters. 4, 12, p. 1228-1232 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    Bach, Anders, Pedersen, T. B. & Strømgaard, Kristian, 2016, In: MedChemComm. 7, 3, p. 531-536 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor

    Nissen, K. B., Andersen, J. J., Haugaard-Kedström, L. M., Bach, Anders & Strømgaard, Kristian, 2015, In: Journal of Medicinal Chemistry. 58, p. 1575-1580 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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