Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2014
  2. Published

    Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors

    Nørager, N. G., Poulsen, Mette Homann, Jensen, A. G., Jeppesen, N. S., Kristensen, Anders Skov & Strømgaard, Kristian, 12 Jun 2014, In: Journal of Medicinal Chemistry. 57, 11, p. 4940-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (prozac)

    Andersen, J., Stuhr-Hansen, N., Zachariassen, L. G., Koldsø, H., Schiøtt, B., Strømgaard, Kristian & Kristensen, Anders Skov, May 2014, In: Molecular Pharmacology. 85, 5, p. 703-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites

    Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, 18 Apr 2014, In: ACS chemical biology. 9, 4, p. 935-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin

    Poulsen, Mette Homann, Lucas, S., Strømgaard, Kristian & Kristensen, Anders Skov, 22 Feb 2014, In: Neurochemical Research. 39, 10, p. 1906-1913 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evaluation of PhTX-74 as Subtype-Selective Inhibitor of GluA2-Containing AMPA Receptors

    Poulsen, Mette Homann, Lucas, S., Strømgaard, Kristian & Kristensen, Anders Skov, Feb 2014, In: Molecular Pharmacology. 85, 2, p. 261-268 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

    Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

    Research output: Contribution to journalJournal articleResearch

  8. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids

    Stuhr-Hansen, N., Padrah, S. & Strømgaard, Kristian, 2014, In: Tetrahedron Letters. 55, 30, p. 4149-4151 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations

    Pedersen, S. W., Pedersen, S. B., Anker, L., Hultqvist, G., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2014, In: Nature Communications. 5, p. 1-11 11 p., 3215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain

    Pedersen, S. W., Hultqvist, G., Strømgaard, Kristian & Jemth, P., 2014, In: PLOS ONE. 9, 4, p. 1-7 7 p., e95619.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2013
  12. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications

    Albertsen, L., Andersen, J. J., Paulsson, J. F., Thomsen, J. K., Norrild, J. C. & Strømgaard, Kristian, 12 Dec 2013, In: A C S Medicinal Chemistry Letters. 4, 12, p. 1228-1232 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Recombinant production of peptide C-terminal α-amides using an engineered intein

    Albertsen, L., Shaw, A. C., Norrild, J. C. & Strømgaard, Kristian, 20 Nov 2013, In: Bioconjugate Chemistry. 24, 11, p. 1883-94 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons

    Nørager, N. G., Jensen, C. B., Rathje, Mette, Andersen, J., Madsen, Kenneth Lindegaard, Kristensen, Anders Skov & Strømgaard, Kristian, 20 Sep 2013, In: A C S Chemical Biology. 8, 9, p. 2033-2041 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations

    Eildal, J. N. N., Hultqvist, G., Balle, T., Stuhr-Hansen, N., Padrah, S., Gianni, S., Strømgaard, Kristian & Jemth, P., 4 Sep 2013, In: Journal of the American Chemical Society. 135, 35, p. 12998-3007 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY

    Albertsen, L., Østergaard, S., Paulsson, J. F., Norrild, J. C. & Strømgaard, Kristian, Sep 2013, In: ChemMedChem. 8, 9, p. 1505-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Preparation of peptide thioesters through fmoc-based solid-phase peptide synthesis by using amino thioesters

    Stuhr-Hansen, N., Wilbek, T. S. & Strømgaard, Kristian, 1 Aug 2013, In: European Journal of Organic Chemistry. 2013, 24, p. 5290-5294 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Energetic pathway sampling in a protein interaction domain

    Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In: Structure. 21, 7, p. 1193-1202

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthetic and mechanistic insight into nosylation of glycine residues

    Stuhr-Hansen, N., Sølling, Theis Ivan & Strømgaard, Kristian, 14 Apr 2013, In: Organic & Biomolecular Chemistry. 11, 14, p. 2288-2293 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

    Fiorentini, M., Bach, Anders, Strømgaard, Kristian, Kastrup, Jette Sandholm Jensen & Gajhede, Michael, Apr 2013, In: Acta Crystallographica. Section D: Biological Crystallography. 69, Pt 4, p. 587-94 8 p.

    Research output: Contribution to journalJournal articleResearch

  21. Published

    UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, J., Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In: Neuropharmacology. 67, p. 193-200 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors

    Poulsen, Mette Homann, Lucas, S., Bach, T. B., Barslund, A. F., Wenzler, C., Jensen, C. B., Kristensen, Anders Skov & Strømgaard, Kristian, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 1171-1181 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions

    Møller, T. C., Wirth, V. F., Roberts, N. I., Bender, J., Bach, Anders, Jacky, B. P. S., Strømgaard, Kristian, Deussing, J. M., Schwartz, Thue W. & Martinez, Karen Laurence, 2013, In: PLOS ONE. 8, 5, e63352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group

    Pedersen, S. W., Armishaw, C. J. & Strømgaard, Kristian, 2013, Peptide synthesis and applications. Humana Press, Vol. 1047. p. 65-80 16 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  25. 2012
  26. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors

    Lucas, S., Poulsen, Mette Homann, Nørager, N. G., Barslund, A. F., Bach, T. B., Kristensen, Anders Skov & Strømgaard, Kristian, 26 Nov 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10297-10301 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    An expanded view of the protein folding landscape of PDZ domains

    Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In: Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A heteromeric snake toxin and the molecular details of pain perception

    Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In: Angewandte Chemie International Edition. 51, 17, p. 4009-4011

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559