Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2023
  2. Published

    Endogenous Retroviral Elements Constitute a Promising Vaccine Antigen Source for Haematological Malignancies

    Thygesen, Christian Bahne, Klausen, M. S., Thuesen, N., Garde, C., Jespersen, A., Grønbæk, Kirsten, Kringelum, J. & Bundgård Sørensen, A. B., 28 Nov 2023, In: Blood. 142, Supplement 1, p. 243-243

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    10-year nationwide trends in incidence, treatment patterns, and mortality of patients with myelodysplastic syndromes in Denmark

    Lauritsen, T. B., Nørgaard, J. M., Dalton, Susanne Oksbjerg, Grønbæk, Kirsten, El-Galaly, T. C. & Østgård, L. S. G., 2023, In: Leukemia Research. 128, 10 p., 107056.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care

    El-Galaly, T. C., Gaidzik, V. I., Gaman, M. A., Antic, D., Okosun, J., Copland, M., Sexl, V., Fielding, A. K., Doeswijk, R., Parker, H., Dreyling, M., Döhner, K., Almeida, A. M., Macintyre, E., Gribben, J. G. & Grønbæk, Kirsten, 2023, In: HemaSphere. 7, 3, 4 p., e842.

    Research output: Contribution to journalEditorialResearch

  5. Published

    A second update on mapping the human genetic architecture of COVID-19

    Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. Published

    Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma

    Granau, Agnete Marie, Andersen, P. A., Jakobsen, T., Taouxi, K., Dalila, N., Mogensen, J. B., Kristensen, L. S., Grønbæk, Kirsten & Dimopoulos, K., 2023, In: Cancers. 15, 2, 15 p., 510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Exploring new prognostic biomarkers in Mantle Cell Lymphoma: a comparison of the circSCORE and the MCL35 score

    Salim, Ruth, Husby, Simon, Winther Eskelund, C., Scott, D. W., Holte, H., Kolstad, A., Räty, R., Ek, S., Jerkeman, M., Geisler, C., Sommer Kristensen, L., Dahl, M. & Grønbæk, Kirsten, 2023, In: Leukemia and Lymphoma. 64, 8, p. 1414-1423

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Frequency and Functional Characterization of RUNX1 Germline Variants in Myeloid Neoplasms

    Nitschke, N. J., Almosailleakh, M., Niu, Yiyuan, Hansen, Jakob Werner, Raaschou-Jensen, K., Jespersen, Jakob Schmidt, Severinsen, M. T., Roug, A. S., Frödin, Morten, Weischenfeldt, Joachim Lütken, Andersen, M. K. & Grønbæk, Kirsten, 2023, In: Human Mutation. 2023, 11 p., 4738660.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Humoral and cellular immune responses after three or four doses of BNT162b2 in patients with hematological malignancies

    Heftdal, L. D., Hamm, S. R., Pérez-Alós, L., Madsen, J. R., Armenteros, J. J. A., Fogh, K., Kronborg, C. C., Vallentin, A. P., Hasselbalch, R. B., Møller, D. L., Hansen, C. B., Pries-Heje, M., Gang, A. O., Ostrowski, S. R., Frikke-Schmidt, R., Sørensen, E., Hilsted, L., Bundgaard, H., Iversen, K., Garred, P. & 2 others, Nielsen, S. D. & Grønbæk, Kirsten, 2023, In: European Journal of Haematology. 111, 2, p. 229-239 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Humoral and cellular immune responses eleven months after the third dose of BNT162b2 an mRNA-based COVID-19 vaccine in people with HIV – a prospective observational cohort study

    Heftdal, Line Dam, Pérez-Alós, L., Hasselbalch, R. B., Hansen, Cecilie Bo, Hamm, S. R., Møller, D. L., Pries-Heje, M., Fogh, K., Gerstoft, Jan, Grønbæk, Kirsten, Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Sørensen, E., Hilsted, L., Bundgård, Henning, Garred, Peter, Iversen, Kasper, Sabin, C. & Nielsen, S. D., 2023, In: EBioMedicine. 93, 9 p., 104661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms

    Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, Morten Rytter, Côme, Christophe Roger Michel, Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, Jakob Schmidt, Schlotmann, Balthasar Clemens, Schöllkopf, C., Raaschou-Jensen, K., Ødum, Niels, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, Kirsten & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model

    Almosailleakh, M., Bentivegna, Sofia, Narcisi, S., Benquet, Sébastien Jean, Gillberg, Linn, Montaño-Almendras, C. P., Savickas, S., Schoof, E. M., Wegener, A., Luche, H., Jensen, Henrik Elvang, Côme, Christophe Roger Michel & Grønbæk, Kirsten, 2023, In: Genes. 14, 10, 1947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Methylation and hydroxymethylation in cancer

    Asmar, F., Gillberg, Linn & Grønbæk, Kirsten, 2023, Epigenetic Cancer Therapy [Second Edition]. 2. ed. Elsevier, p. 11-37 27 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  15. Published

    Monocytosis in primary care and risk of haematological malignancies

    Christensen, M. E., Siersma, Volkert Dirk, Kriegbaum, Margit, Lind, B. S., Samuelsson, J., Østgård, L. S. G., Grønbæk, Kirsten & Andersen, Christen Bertel L, 2023, In: European Journal of Haematology. 110, 4, p. 362-370 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high-dose chemotherapy independent of MIPI and complement established high-risk factors

    Gerdtsson, A. S., de Matos Rodrigues, J., Eskelund, C. W., Husby, Simon, Grønbæk, Kirsten, Räty, R., Kolstad, A., Geisler, C., Porwit, A., Jerkeman, M. & Ek, S., 2023, In: Haematologica. 108, 4, p. 1092-1104 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    ProGraME: A novel flow cytometry algorithm for the diagnosis of low-risk myelodysplastic syndromes in patients with cytopenia

    Therkelsen, J., Træden, D. W., Schjødt, I., Andersen, M. K., Sjö, Lene Dissing, Hansen, Jakob Werner, Grønbæk, Kirsten & Dimopoulos, K., 2023, In: European Journal of Haematology. 111, 6, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Second primary malignancies in patients with lymphoma in Denmark after high-dose chemotherapy and autologous haematopoietic stem-cell transplantation: a population-based, retrospective cohort study

    Trab, Trine, Baech, J., Jakobsen, L. H., Husby, S., Severinsen, M. T., Eloranta, S., Gørløv, J. S., Jørgensen, J. M., Gudbrandsdottir, S., Larsen, T. S., Brown, Peter de Nully, Grønbæk, Kirsten, Smedby, K. E. & El-Galaly, T. C., 2023, In: The Lancet Haematology. 10, 10, p. e838-e848 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 37722667