Jonas Thue Treebak
Associate Professor
Treebak Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
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Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965
Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle
Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity
Andersson, U., Treebak, Jonas Thue, Nielsen, J. N., Smith, K. L., Abbott, C. R., Small, C. J., Carling, D. & Richter, Erik A., 2005, In: Biochemical and Biophysical Research Communications. 329, 2, p. 719-725 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise
Ashcroft, Stephen Paul, Jepsen, Sara Lind, Ehrlich, Amy M, Treebak, Jonas Thue, Holst, Jens Juul & Zierath, Juleen R, 2023, In: STAR Protocols. 4, 1, 11 p., 101985.Research output: Contribution to journal › Journal article › Research › peer-review
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PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute exercise remodels promoter methylation in human skeletal muscle
Barrès, Romain, Yan, J., Egan, B., Treebak, Jonas Thue, Rasmussen, M., Fritz, T., Caidahl, K., Krook, A., O'Gorman, D. J. & Zierath, Juleen R, 7 Mar 2012, In: Cell Metabolism. 15, 3, p. 405-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.Research output: Contribution to journal › Journal article › Research › peer-review
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Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity
Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, , 2021, In: Molecular Metabolism. 53, 101271.Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status
Basse, A. L., Kellezi, Emilie Dalbram, Larsson, L., Gerhart-Hines, Zach, Zierath, Juleen R & Treebak, Jonas Thue, 2018, In: Frontiers in Physiology. 9, p. 1-12 12 p., 1198.Research output: Contribution to journal › Journal article › Research › peer-review
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Bed Rest-Induced Changes in TBC1D4 Phosphorylation and Glycogen Synthase Activity. Effects of Acute Exercise
Bienso, R. S., Ringholm, S., Lundby, C., Achman-Andersen, N. J., Plomgaard, Peter Stendahl, Krogh-Madsen, Rikke, Kiilerich, K., Guerra, B., Treebak, Jonas Thue, Calbet, J. A., Pilegaard, Henriette & Wojtaszewski, J. J. F., 2010, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
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GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance
Biensø, R. S., Jørgensen, Stine Ringholm, Kiilerich, K., Aachmann-Andersen, N. J., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2012, In: Diabetes. 61, 5, p. 1090-1099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099
Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.Research output: Contribution to journal › Comment/debate › Research
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AMP-activated protein kinase regulates nicotinamide phosphoribosyl transferase expression in skeletal muscle
Brandauer, J., Vienberg, S. G., Andersen, M. A., Jørgensen, Stine Ringholm, Risis, S., Larsen, P., Kristensen, Jonas Møller, Frøsig, C., Leick, L., Fentz, J., Jørgensen, S. B., Kiens, Bente, Wojtaszewski, Jørgen F P, Richter, Erik A., Zierath, Juleen R, Goodyear, L. J., Pilegaard, Henriette & Treebak, Jonas Thue, 2013, In: Journal of Physiology. 591, p. 5207-5220 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic AICAR treatment, but not voluntary exercise training, increases nicotinamide phosphoribosyl transferase (Nampt) protein expression in an AMPK-dependent manner in mouse quadriceps muscle
Brandauer, J. & Treebak, Jonas Thue, 2011, In: FASEB Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise-induced up-regulation of skeletal muscle Nampt protein is independent of alpha 2 AMP-activated protein kinase
Brandauer, J., Vienberg, S. G., Andersen, M. A., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Richter, Erik A. & Treebak, Jonas Thue, 2013, In: FASEB Journal. 27, 1 p., lb806.Research output: Contribution to journal › Conference abstract in journal › Research
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AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD
Brandauer, J., Andersen, M. A., Kellezi, H., Risis, S., Frøsig, C., Vienberg, S. G. & Treebak, Jonas Thue, Mar 2015, In: Frontiers in Physiology. 6, 16 p., 85.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise
Brandão, B. B., Madsen, S., Rabiee, A., Oliverio, M., Ruiz, G. P., Ferrucci, D. L., Branquinho, J. L., Razolli, D., Pinto, S., Nielsen, T. S., Festuccia, W. T., Martins, A. S., Guerra, B. A., Knittel, T. L., Søgaard, D., Larsen, S., Helge, J. W., Brandauer, J., Velloso, L. A., Emanuelli, B. & 6 others, , 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 38, p. 23932-23941Research output: Contribution to journal › Journal article › Research › peer-review
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Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content
Chubanava, Sabina & Treebak, Jonas Thue, 2023, In: Experimental Gerontology. 173, 112109.Research output: Contribution to journal › Review › Research › peer-review
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Impairments in site-specific AS160 phosphorylation and effects of exercise training
Consitt, L. A., Van Meter, J., Newton, C. A., Collier, D. N., Dar, M. S., Wojtaszewski, Jørgen F P, Treebak, Jonas Thue, Tanner, C. J. & Houmard, J. A., 2013, In: Diabetes. 62, 10, p. 3437-3447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ellagic acid prevents myocardial infarction-induced left ventricular diastolic dysfunction in ovariectomized rats
Costa, B. M., Mengal, V., Brasil, G. A., Peluso, A. A., Treebak, Jonas Thue, Endlich, P. W., de Almeida, S. A. & de Abreu, G. R., 2022, In: Journal of Nutritional Biochemistry. 105, 9 p., 108990.Research output: Contribution to journal › Journal article › Research › peer-review
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Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action
Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes
Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.Research output: Contribution to journal › Journal article › Research › peer-review
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NAD+ and NAFLD - Caution, Causality, and Careful Optimism
Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice
Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 7974
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AMPK and insulin action: Responses to ageing and high fat diet
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Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice
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488
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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