Jesper M. Mathiesen

Jesper M. Mathiesen

Associate Professor


Publication year:
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1 - 10 out of 39Page size: 10
  1. 2024
  2. Published

    A µ-opioid receptor modulator that works cooperatively with naloxone

    O’Brien, E. S., Rangari, V. A., El Daibani, A., Eans, S. O., Hammond, H. R., White, E., Wang, H., Shiimura, Y., Krishna Kumar, K., Jiang, Q., Appourchaux, K., Huang, W., Zhang, C., Kennedy, B. J., Mathiesen, Jesper M., Che, T., McLaughlin, J. P., Majumdar, S. & Kobilka, B. K., 2024, In: Nature. 631, 8021, p. 686-693

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor

    He, F., Wu, C. G., Gao, Y., Rahman, Sabrina Nalini, Zaoralová, M., Papasergi-Scott, M. M., Gu, T. J., Robertson, M. J., Seven, A. B., Li, L., Mathiesen, Jesper M. & Skiniotis, G., 2024, In: Nature. 626, p. 1141–1148

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor

    Gaiser, B. I., Danielsen, Mia, Xu, X., Røpke Jørgensen, K., Fronik, P., Marcher, Emil, Wróbel, T. M., Liu, X., Mathiesen, Jesper M. & Sejer Pedersen, D., 2024, In: Journal of Medicinal Chemistry. 67, 13, p. 11053–11068

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Accepted/In press

    Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor

    Batebi, H., Pérez-Hernández, G., Rahman, Sabrina Nalini, Lan, B., Kamprad, A., Shi, M., Speck, D., Tiemann, Johanna Katarina Sofie, Guixà-González, R., Reinhardt, F., Stadler, P. F., Papasergi-Scott, M. M., Skiniotis, G., Scheerer, P., Kobilka, B. K., Mathiesen, Jesper M., Liu, X. & Hildebrand, P. W., 2024, (Accepted/In press) In: Nature Structural and Molecular Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    Glycine: a long-sought novel ligand for GPR158

    Rosenkilde, Mette & Mathiesen, Jesper M., 2023, In: Trends in Pharmacological Sciences. 44, 8, p. 489-491

    Research output: Contribution to journal › Letter › Research › peer-review

  8. 2022
  9. Published

    Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells

    Deng, Y., Moo, Ee Von, Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, Jesper M. & Bräuner, Hans, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2021
  11. Published

    Asymmetric activation of the calcium-sensing receptor homodimer

    Gao, Y., Robertson, M. J., Rahman, Sabrina Nalini, Seven, A. B., Zhang, C., Meyerowitz, J. G., Panova, O., Hannan, F. M., Thakker, R. V., Bräuner, Hans, Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 455-459

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    G-protein activation by a metabotropic glutamate receptor

    Seven, A. B., Barros-Álvarez, X., de Lapeyrière, M., Papasergi-Scott, M. M., Robertson, M. J., Zhang, C., Nwokonko, R. M., Gao, Y., Meyerowitz, J. G., Rocher, J. P., Schelshorn, D., Kobilka, B. K., Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 450-454

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2020
  14. Published

    Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

    Boesgaard, M. W., Harpsøe, Kasper, Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, Jesper M., König, G. M., Kostenis, E., Gloriam, David E. & Bräuner, Hans, 2020, In: Journal of Biological Chemistry. 295, 40, p. 13850-13861

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

    Møller, T. C., Pedersen, M. F., van Senten, Jeffrey Roy, Seiersen, S. D., Mathiesen, Jesper M., Bouvier, M. & Bräuner, Hans, 2020, In: Scientific Reports. 10, 1, 13 p., 17395.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4873159