Jens Lykkesfeldt

Jens Lykkesfeldt

Professor


  1. 1991
  2. Published

    2-Nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench

    Halkier, Barbara Ann, Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 487-491 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1993
  4. Published

    Synthesis of benzylglucosinolate in Tropaeolum majus L. Isothiocyanates as potent enzyme inhibitors

    Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1993, In: Plant Physiology. 102, 2, p. 609-613 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Nitrosamindannende håndkøbspraeparater?

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 13 Dec 1993, In: Ugeskrift for Laeger. 155, 50, p. 4106-4107 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. 1994
  7. Published

    Simultaneous determination of urinary free cortisol and 6*Gb-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity

    Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, p. 23-29

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity

    Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 3 Oct 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, 1, p. 23-29 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 1995
  10. Published
  11. Published

    Involvment of cytochrome P450 in Oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomale enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba

    Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, B. A., 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine

    Rasmussen, B. B., Mäenpää, J., Pelkonen, O., Loft, Steffen, Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Brøsen, K., 1995, In: British Journal of Clinical Pharmacology. 39, p. 151-159

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L.

    Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, Barbara Ann, 19 Dec 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 26, p. 12505-12509 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 1996
  15. Published

    Effect of smoking cessation on plasma ascorbic acid concentration

    Lykkesfeldt, Jens, Priemé, H., Loft, Steffen & Poulsen, Henrik Enghusen, 13 Jul 1996, In: B M J (Clinical Research Edition). 313, 7049, p. 91

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 1997
  17. Published

    Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3

    Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 1998
  19. Published

    Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

    Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, Jens, Vinarsky, V., Bartholomew, J. C., Song, M. & Ames, B. N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, p. 9562-9566 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation

    Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion

    Poulsen, H. E., Loft, S., Prieme, H., Vistisen, K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Oxidative DNA damage in vivo: Relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion

    Poulsen, Henrik Enghusen, Loft, Steffen, Prieme, H., Vistisen, K. K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Artemisinin induces omeprazole metabolism in human beings

    Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Van Huong, N., Niêu, N. T., Sy, N. D., Lykkesfeldt, Jens & Công, L. D., 1 Aug 1998, In: Clinical Pharmacology and Therapeutics. 64, 2, p. 160-167 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age

    Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 1999
  26. Published

    (R)-alfa-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

    Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 1999, In: The FASEB Journal. 13, p. 411-4418 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age

    Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age

    Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    (R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

    Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2000
  31. Published

    Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes

    Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.

    Research output: Contribution to conferencePaperResearch

  33. Published
  34. Published

    Morphine concentration in plasma andcerebrospinal fluid in the anaesthetised pig after a single intravenous administration

    Lykkegaard, K., Lykkesfeldt, Jens & Svendsen, O., 2000. 1 p.

    Research output: Contribution to conferencePaperResearch

  35. Published

    On the possible connection between vitamin C, cardiovirus and guinea pig lameness

    Clausen, F. B., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2000, Ikke angivet. Laboratory Animals Ltd, p. 101-104 4 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  36. 2001
  37. Published

    Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry

    Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs

    Weng Larsen, S., Reinvar, E., Svendsen, O., Lykkesfeldt, Jens, Friis, G. J. & Larsen, C., 2001, In: Internation Journal of Pharmaceutics. 230, p. 67-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment

    Christen, S., Schaper, M., Lykkesfeldt, Jens, Siegenthaler, C., Bifrare, Y., Banic, S. O., Leib, S. L. & Täuber, M. G., 2001, In: Free Radical Biology & Medicine. 31, 6, p. 754-762 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2002
  41. Published

    Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.

    Research output: Contribution to conferencePaperResearch

  42. Published

    Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis

    Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2002, In: Journal of Veterinary Pharmacology and Therapeutics. 25, 5, p. 335-342 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Evaluation of a single dose and a split-dose regimen of danofloxacin against Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2002.

    Research output: Contribution to conferencePaperResearch

  45. Published

    Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

    Hagen, T. M., Liu, J., Lykkesfeldt, Jens, Wehr, C. M., Ingersoll, R. T., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 4, p. 1870-1875 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation

    Jiang, Q., Lykkesfeldt, Jens, Shigenaga, M. K., Shigeno, E. T., Christen, S. & Ames, B. N., 2002, In: Free Radical Biology & Medicine. 33, 11, p. 1534-1542 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Increased oxidative damage in vitamin C deficiency is accompanied by induction of ascorbic acid recycling capacity in young but not mature guinea pigs

    Lykkesfeldt, Jens, 2002, In: Free Radical Research. 36, 5, p. 567-574 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Measurement of ascorbic acid and dehydroascorbic acid in biological samples

    Lykkesfeldt, Jens, 2002, Current protocols in toxicology. Maines, M., Costa, L. G., Hodson, E., Reed, D. J. & Sipes, I. G. (eds.). New York: Wiley, p. 7.6.1-7.6.15 15 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  49. 2003
  50. Published

    Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Effect of smoking on erythorbic acid pharmacokinetics

    Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 271-277 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Skaanild, M. T., Angen, Ø., Nielsen, Jens Peter & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 261-270 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs

    Wiuff, C., Lykkesfeldt, Jens, Svendsen, O. & Aarestrup, F. M., 2003, In: Research in Veterinary Science. 75, 3, p. 185-193 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2004
  56. Published

    Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone

    Böttcher, T., Ren, H., Goiny, M., Gerber, J., Lykkesfeldt, Jens, Kuhnt, U., Lotz, M., Bunkowski, S., Werner, C., Schau, I., Spreer, A., Christen, S. & Nau, R., 2004, In: Journal of Neurochemistry. 91, 6, p. 1450-1460 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men 1-3

    Turnlund, J. R., Jacob, R. A., Keen, C. L., Strain, J. J., Kelly, D. S., Domek, J. M., Keyes, W. R., Ensunsa, J. L., Lykkesfeldt, Jens & Coulter, J., 2004, In: American Journal of Clinical Nutrition. 79, 6, p. 1037-1044 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Optimized treatment regimens for enrofloxacin in pigs limits selection for resistance in salmonella and coliforms

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2004. 1 p.

    Research output: Contribution to conferencePaperResearch

  59. Published

    Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea

    Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2004, In: American Journal of Veterinary Research. 65, p. 992-995 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2004, In: British Journal of Nutrition. 92, 2, p. 203-206 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Vitamin C and oxidative damage to DNA: chapter 11

    Poulsen, Henrik Enghusen, Møller, P., Lykkesfeldt, Jens, Weimann, A. & Loft, S., 2004, Vitamin C. Asard, H., May, J. M. & Smirnoff, N. (eds.). Oxford: BIOS Scientific Publishers, p. 189-202 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  62. Published

    Vitamin C pharmacokinetics of plain and slow release formulations in smokers

    Viscovich, M., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2004, In: Clinical Nutrition. 23, 5, p. 1043-1050 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Vitamin C supplementation decreases oxidative DNA damage in mononuclear bood cells of smokers

    Møller, P., Viscovich, M., Lykkesfeldt, Jens, Loft, S., Jensen, A. & Poulsen, H. E., 2004, In: European Journal of Nutrition. 43, p. 267-274 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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