Jens Bukh
Professor
Virology
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-13-84
Member of:
- 2021
- Published
In vitro Characterization of Fitness and Convalescent Antibody Neutralization of SARS-CoV-2 Cluster 5 Variant Emerging in Mink at Danish Farms
Lassaunière, R., Fonager, J., Rasmussen, M., Frische, A., Polacek, C., Rasmussen, T. B., Lohse, L., Belsham, Graham John, Underwood, Alexander Paul James, Winckelmann, A. A., Bollerup, S., Bukh, Jens, Weis, Nina, Sækmose, S. G., Aagaard, B., Alfaro-Núñez, A., Mølbak, Kåre, Bøtner, A. & Fomsgaard, A., 2021, In: Frontiers in Microbiology. 12, 9 p., 698944.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro adaptation and characterization of attenuated hypervariable region 1 swap chimeras of hepatitis C virus
Olesen, C. H., Augestad, Elias Honerød, Troise, F., Bukh, Jens & Prentø, Jannick, 2021, In: PLOS Pathogens. 17, July, 29 p., e1009720.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antigenic and immunogenic evaluation of permutations of soluble hepatitis C virus envelope protein E2 and E1 antigens
Prentø, Jannick, Janitzek, C. M., Velázquez-Moctezuma, R., Goksøyr, L., Olsen, Rebecca Wendelboe, Fanalista, Margherita, Augestad, Elias Honerød, Thrane, Susan, Pihl, A. F., Gottwein, Judith Margarete, Sander, Adam F. & Bukh, Jens, 2021, In: PLoS ONE. 16, e0255336.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a novel hepatitis C virus genotype 1 subtype from a patient failing 4 weeks of glecaprevir-pibrentasvir treatment
Pedersen, M. S., Fahnøe, Ulrik, Madsen, L. W., Christensen, P. B., Øvrehus, A. & Bukh, Jens, 2021, In: Microbiology resource announcements. 10, 41, e00755.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of ion-channel inhibitors amantadine, memantine and rimantadine for the treatment of SARS-CoV-2 in vitro
Zhou, Y., Gammeltoft, Karen Anbro, Galli, Andrea, Offersgaard, Anna Falden, Fahnøe, Ulrik, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Viruses. 13, 10, 2082.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins
Chen, F., Tzarum, N., Lin, X., Giang, E., Velázquez-Moctezuma, R., Augestad, Elias Honerød, Nagy, K., He, L., Hernandez, M., Fouch, M. E., Grinyó, A., Chavez, D., Doranz, B. J., Prentø, Jannick, Stanfield, R. L., Lanford, R., Bukh, Jens, Wilson, I. A., Zhu, J. & Law, M., 2021, In: Immunity. 54, 4, p. 781-796.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global evolutionary analysis of chronic hepatitis C patients revealed significant effect of baseline viral resistance, including novel non-target sites, for DAA-based treatment and retreatment outcome
Fahnøe, Ulrik, Pedersen, M. S., Sølund, C., Ernst, A., Krarup, H. B., Røge, B. T., Christensen, P. B., Laursen, A. L., Gerstoft, Jan, Thielsen, P., Madsen, Lone Galmstrup, Pedersen, A. G., Schønning, Kristian, Weis, Nina & Bukh, Jens, 2021, In: Journal of Viral Hepatitis. 28, 2, p. 302-316Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro
Gammeltoft, Karen Anbro, Zhou, Y., Duarte Hernandez, C. R., Galli, Andrea, Offersgaard, Anna Falden, Costa, Rui, Pham, Long, Fahnøe, Ulrik, Feng, S., Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Bukh, Jens & Gottwein, Judith Margarete, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 9, e02680-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis C virus envelope protein dynamics and the link to hypervariable region 1
Augestad, Elias Honerød, Bukh, Jens & Prentø, Jannick, 2021, In: Current Opinion in Virology. 50, p. 69-75 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
In vitro efficacy of artemisinin-based treatments against SARS-CoV-2
Zhou, Y., Gilmore, K., Ramirez Almeida, Santseharay, Settels, E., Gammeltoft, Karen Anbro, Pham, Long, Fahnøe, Ulrik, Feng, S., Offersgaard, Anna Falden, Trimpert, J., Bukh, Jens, Osterrieder, K., Gottwein, Judith Margarete & Seeberger, P. H., 2021, In: Scientific Reports. 11, 14571.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inferior cure rate in pilot study of 4-week glecaprevir/pibrentasvir treatment with or without ribavirin of chronic hepatitis C
Madsen, L. W., Christensen, P. B., Fahnøe, Ulrik, Pedersen, M. S., Bukh, Jens & Øvrehus, A., 2021, In: Liver International. 41, 11, p. 2601-2610Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid Droplets Accumulation during Hepatitis C Virus Infection in Cell-Culture Varies among Genotype 1-3 Strains and Does Not Correlate with Virus Replication
Galli, Andrea, Ramirez Almeida, Santseharay & Bukh, Jens, 2021, In: Viruses. 13, 3, 389.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutralisation titres against SARS-CoV-2 are sustained 6 months after onset of symptoms in individuals with mild COVID-19
Underwood, Alexander Paul James, Sølund, C., Fernandez-Antunez, C., Villadsen, S. L., Winckelmann, A. A., Bollerup, S., Mikkelsen, L. S., Sørensen, A. L., Feng, S., Fahnøe, Ulrik, Lassauniere, R., Fomsgaard, A., Ramirez Almeida, Santseharay, Weis, Nina & Bukh, Jens, 2021, In: EBioMedicine. 71, 103519.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overcoming culture restriction for SARS-CoV-2 in human cells facilitates the screening of compounds inhibiting viral replication
Ramirez Almeida, Santseharay, Fernandez-Antunez, C., Galli, Andrea, Underwood, Alexander Paul James, Pham, Long, Ryberg, Line Abildgaard, Feng, S., Pedersen, M. S., Mikkelsen, L. S., Belouzard, S., Dubuisson, J., Sølund, C., Weis, Nina, Gottwein, Judith Margarete, Fahnøe, Ulrik & Bukh, Jens, 2021, In: Antimicrobial Agents and Chemotherapy. 65, 7, 20 p., e00097-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathogenesis, miR-122 gene-regulation, and protective immune responses after acute equine hepacivirus infection
Tomlinson, J. E., Wolfisberg, R., Fahnøe, Ulrik, Patel, R. S., Trivedi, S., Kumar, A., Sharma, H., Nielsen, L., McDonough, S. P., Bukh, Jens, Tennant, B. C., Kapoor, A., Rosenberg, B. R., Rice, C. M., Divers, T. J., Van de Walle, G. R. & Scheel, Troels Kasper Høyer, 2021, In: Hepatology. 74, 3, p. 1148-1163Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sars-cov-2 production in a scalable high cell density bioreactor
Offersgaard, Anna Falden, Hernandez, C. R. D., Pihl, A. F., Costa, Rui, Venkatesan, N. P., Lin, X., Pham, Long, Feng, S., Fahnøe, Ulrik, Scheel, Troels Kasper Høyer, Ramirez Almeida, Santseharay, Reichl, U., Bukh, Jens, Genzel, Y. & Gottwein, Judith Margarete, 2021, In: Vaccines. 9, 7, 706.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vaccines against hepatitis C: A travel into neutralisation space
Bukh, Jens, 2021, In: Gut. 70, 9, p. 1609-1610 2 p., 323377.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
STOP-HCV Consortium, S. C., 2021, In: Nature Communications. 12, 1, 11 p., 6105.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12437
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414
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Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
Research output: Contribution to journal › Review › Research › peer-review
Published -
374
downloads
Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
344
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Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry
Research output: Contribution to journal › Review › Research › peer-review
Published