Inge Marie Svane
Clinical Professor
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Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome
Araujo B de Lima, V., Borch, A., Hansen, M., Draghi, A., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, Apr 2020, In: Cytotherapy. 22, 4, p. 204-213 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Overall survival at 5 years of follow-up in a phase III trial comparing ipilimumab 10 mg/kg with 3 mg/kg in patients with advanced melanoma
Ascierto, P. A., Del Vecchio, M., Mackiewicz, A., Robert, C., Chiarion-Sileni, V., Arance, A., Lebbé, C., Svane, I. M., Mcneil, C., Rutkowski, P., Loquai, C., Mortier, L., Hamid, O., Bastholt, L., Dreno, B., Schadendorf, D., Garbe, C., Nyakas, M., Grob, J. J., Thomas, L. & 10 others, , 2020, In: Journal for ImmunoTherapy of Cancer. 8, 1, e000391.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic biomarkers in melanoma of the ocular region: What the medical oncologist should know
Bol, K. F., dqp123, dqp123, Heegaard, Steffen, Kiilgaard, Jens Folke & Svane, Inge Marie, 2020, In: International Journal of Molecular Sciences . 21, 15, p. 1-14 14 p., 5231.Research output: Contribution to journal › Review › Research › peer-review
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Future role for adoptive T-cell therapy in checkpoint inhibitor-resistant metastatic melanoma
Borch, T. H., Andersen, R., Ellebaek, E., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, e000668.Research output: Contribution to journal › Journal article › Research › peer-review
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Tertiary lymphoid structures improve immunotherapy and survival in melanoma
Cabrita, R., Lauss, M., Sanna, A., Donia, M., Skaarup Larsen, M., Mitra, S., Johansson, I., Phung, B., Harbst, K., Vallon-Christersson, J., van Schoiack, A., Lövgren, K., Warren, S., Jirström, K., Olsson, H., Pietras, K., Ingvar, C., Isaksson, K., Schadendorf, D., Schmidt, H. & 5 others, , 2020, In: Nature. 577, p. 561-565Research output: Contribution to journal › Journal article › Research › peer-review
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T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road
Crowther, M. D., Svane, Inge Marie & Met, Özcan, 2020, In: Cells. 9, 7, 18 p., 1588.Research output: Contribution to journal › Review › Research › peer-review
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Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1
Crowther, M. D., Dolton, G., Legut, M., Caillaud, M. E., Lloyd, A., Attaf, M., Galloway, S. A. E., Rius, C., Farrell, C. P., Szomolay, B., Ager, A., Parker, A. L., Fuller, A., dqp123, dqp123, McCluskey, J., Rossjohn, J., Svane, Inge Marie, Phillips, J. D. & Sewell, A. K., 2020, In: Nature Immunology. 21, 2, p. 178-185 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma
Ferrucci, P. F., Di Giacomo, A. M., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Stephens, R., Svane, Inge Marie, Lotem, M., Abu-Amna, M., Gasal, E., Ghori, R., Diede, S. J., Croydon, E. S., Ribas, A., Ascierto, P. A. & KEYNOTE-022 international team, K. I. T., 2020, In: Journal for ImmunoTherapy of Cancer. 8, 2, 8 p., e001806.Research output: Contribution to journal › Journal article › Research › peer-review
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CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer
Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.Research output: Contribution to journal › Journal article › Research › peer-review
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Qualitative analysis of tumor-infiltrating lymphocytes across human tumor types reveals a higher proportion of bystander CD8+ T cells in non-melanoma cancers compared to melanoma
Gokuldass, A., Draghi, A., Papp, K., Borch, T. H., Nielsen, M., Westergaard, M. C. W., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Özcan, Harbst, K., Lauss, M., Soraggi, S., Csabai, I., Szállási, Z., Jönsson, G., Svane, Inge Marie & dqp123, dqp123, 2020, In: Cancers. 12, 11, p. 1-15 15 p., 3344.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations
Hansen, U. K., Ramskov, S., Bjerregaard, A. M., Borch, A., Andersen, R., Draghi, A., dqp123, dqp123, Bentzen, A. K., Marquard, A. M., Szallasi, Z., Eklund, A. C., Svane, Inge Marie & Hadrup, S. R., 2020, In: Frontiers in Immunology. 11, 373.Research output: Contribution to journal › Journal article › Research › peer-review
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Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade
Jensen, C., Sinkeviciute, D., Madsen, D. H., Onnerfjord, P., Hansen, M., Schmidt, H., Karsdal, M. A., Svane, Inge Marie & Willumsen, N., 2020, In: Cancers. 12, 10, p. 1-15 2786.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial
Jørgensen, N. G., Klausen, U., Grauslund, J. H., Helleberg, C., Aagaard, T. G., Do, T. H., Ahmad, S. M., Olsen, L. R., Klausen, T. W., Breinholt, M. F., Hansen, M., Martinenaite, E., Met, Özcan, Svane, Inge Marie, Knudsen, L. M. & Andersen, Mads Hald, 2020, In: Frontiers in Immunology. 11, 11 p., 595035.Research output: Contribution to journal › Journal article › Research › peer-review
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Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer
Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
Litchfield, K., Reading, J. L., Lim, E. L., Xu, H., Liu, P., Al-bakir, M., Wong, Y. N. S., Rowan, A., Funt, S. A., Merghoub, T., Perkins, D., Lauss, M., Svane, Inge Marie, Jönsson, G., Herrero, J., Larkin, J., Quezada, S. A., Hellmann, M. D., Turajlic, S. & Swanton, C., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro 4-1BB stimulation promotes expansion of CD8+ tumor-infiltrating lymphocytes from various sarcoma subtypes
Nielsen, M., Krarup-Hansen, Anders, Hovgaard, D., Petersen, Michael Mørk, Loya, Anand Chainsukh, Westergaard, M. C. W., Svane, Inge Marie & Junker, N., 2020, In: Cancer Immunology, Immunotherapy. 69, p. 2179-2191Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of risk factors and efficacy of medical management of immune-related hepatotoxicity in real-world patients with metastatic melanoma treated with immune checkpoint inhibitors
Romanski, N. A., Holmstroem, R. B., Ellebaek, E. & Svane, Inge Marie, 2020, In: European Journal of Cancer. 130, p. 211-218Research output: Contribution to journal › Journal article › Research › peer-review
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Cutaneous adverse reactions to anti–PD-1 treatment—A systematic review
Simonsen, Anne Birgitte Nørremark, Kaae, Jeanette, Ellebaek, E., Svane, Inge Marie & Zachariae, Claus, 1 Nov 2020, In: Journal of the American Academy of Dermatology. 83, 5, p. 1415-1424 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Improved progression-free long-term survival of a nation-wide patient population with metastatic melanoma
Soerensen, A. V., Ellebaek, E., Bastholt, L., Schmidt, H., dqp123, dqp123 & Svane, Inge Marie, 2020, In: Cancers. 12, 9, p. 1-11 11 p., 2591.Research output: Contribution to journal › Journal article › Research › peer-review
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The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines
Weis-Banke, S. E., Hübbe, M. L., Holmström, M. O., Jørgensen, M. A., Bendtsen, S. K., Martinenaite, E., Carretta, M., Svane, Inge Marie, Ødum, Niels, Pedersen, A. W., Met, Özcan, Madsen, D. H. & Andersen, Mads Hald, 2020, In: OncoImmunology. 9, 1, 16 p., 1771142.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer
Westergaard, M. C. W., Milne, K., Pedersen, M., Hasselager, T., Olsen, L. R., Anglesio, M. S., Borch, T. H., Kennedy, M., Briggs, G., Ledoux, S., Kreuzinger, C., Decken, I. V. D., Donia, M., Castillo-Tong, D. C., Nelson, B. H. & Svane, Inge Marie, 2020, In: Cancers. 12, 12, 19 p., 3828.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4054758
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Research output: Contribution to journal › Journal article › Research › peer-review
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258
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Research output: Contribution to journal › Journal article › Research › peer-review
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189
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
Research output: Contribution to journal › Journal article › Research › peer-review
Published