Inge Marie Svane
Clinical Professor
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The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy
Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437Research output: Contribution to journal › Journal article › Research › peer-review
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High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals
Holmström, M. O., Ahmad, S. M., Klausen, U., Bendtsen, S. K., Martinenaite, E., Riley, C. H., Svane, Inge Marie, Kjær, L., Skov, V., Ellervik, Christina, Pallisgaard, N., Hasselbalch, H. C. & Andersen, Mads Hald, 2019, In: Blood Cancer Journal. 9, 2, 8.Research output: Contribution to journal › Journal article › Research › peer-review
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The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms
Holmström, M. O., Riley, C. H., Svane, Inge Marie, Hasselbalch, H. C. & Andersen, Mads Hald, Dec 2016, In: Leukemia. 30, 12, p. 2413-2416 14 p.Research output: Contribution to journal › Letter › Research › peer-review
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Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner
Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancerimmunterapi til behandling af hæmatologisk cancer
Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.Research output: Contribution to journal › Journal article › Research › peer-review
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The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms
Holmström, M. O., Hjortso, M. D., Ahmad, S. M., Met, Özcan, Martinenaite, E., Riley, C., Straten, P., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: Leukemia. 31, p. 495-498Research output: Contribution to journal › Letter › Research › peer-review
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Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response
Holmström, M. O., Riley, C. H., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 6, e1433521.Research output: Contribution to journal › Journal article › Research › peer-review
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of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes
Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.Research output: Contribution to journal › Journal article › Research › peer-review
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The Danish Melanoma Database
Hølmich, Lisbet Rosenkrantz, Klausen, S., Spaun, E., Schmidt, G., Gad, D., Svane, Inge Marie, Schmidt, H., Lorentzen, H. F. & Ibfelt, E. H., 25 Oct 2016, In: Clinical Epidemiology. 8, p. 543-548 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transfection of tumor-infiltrating T cells with mRNA encoding CXCR2
Idorn, M., thor Straten, E. P., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Rhoads, R. E. (ed.). Springer, Vol. 1428. p. 261-276 16 p. (Methods in Molecular Biology, Vol. 1428).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients
Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-lasting Disease Stabilization in the Absence of Toxicity in Metastatic Lung Cancer Patients Vaccinated with an Epitope Derived from Indoleamine 2,3 Dioxygenase
Iversen, T. Z., Engell-Noerregaard, L., Ellebaek, E., Andersen, R. S., Larsen, S. K., Bjoern, J., Zeyher, C., Gouttefangeas, C., Thomsen, B. M., Holm, B., Thor Straten, P., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 1 Jan 2014, In: Clinical Cancer Research. 20, 1, p. 221-232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Targeting of Indoleamine 2,3 Dioxygenase -Mediated Immune Escape in Cancer
Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, Jan 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 1, p. 19-24 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Predictors of responses to immune checkpoint blockade in advanced melanoma
Jacquelot, N., Roberti, M. P., Enot, D. P., Rusakiewicz, S., Ternès, N., Jegou, S., Woods, D. M., Sodré, A. L., Hansen, M., Meirow, Y., Sade-Feldman, M., Burra, A., Kwek, S. S., Flament, C., Messaoudene, M., Duong, C. P. M., Chen, L., Kwon, B. S., Anderson, A. C., Kuchroo, V. K. & 30 others, , 2017, In: Nature Communications. 8, 13 p., 592.Research output: Contribution to journal › Journal article › Research › peer-review
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Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma
Jansen, Y. J. L., Rozeman, E. A., Mason, R., Goldinger, S. M., Geukes Foppen, M. H., Højberg, L., Schmidt, H., van Thienen, J. V., Haanen, J. B. A. G., Tiainen, L., Svane, I. M., Mäkelä, S., Seremet, T., Arance, A., Dummer, R., Bastholt, L., Nyakas, M., Straume, O., Menzies, A. M., Long, G. V. & 3 others, , 2019, In: Annals of Oncology. 30, 7, p. 1154-1161 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
Jensen, C., Madsen, D. H., Hansen, M., Schmidt, H., Svane, Inge Marie, Karsdal, M. A. & Willumsen, N., 2018, In: Journal for ImmunoTherapy of Cancer. 6, 1, p. 1-10 10 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
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Granzyme B Degraded Type IV Collagen Products in Serum Identify Melanoma Patients Responding to Immune Checkpoint Blockade
Jensen, C., Sinkeviciute, D., Madsen, D. H., Onnerfjord, P., Hansen, M., Schmidt, H., Karsdal, M. A., Svane, Inge Marie & Willumsen, N., 2020, In: Cancers. 12, 10, p. 1-15 2786.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
Jespersen, H., Lindberg, M. F., dqp123, dqp123, Söderberg, E. M. V., Andersen, R., Keller, U., Ny, L., Svane, Inge Marie, Nilsson, L. M. & Nilsson, J. A., 2017, In: Nature Communications. 8, 10 p., 707.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application
Junker, N., Thor Straten, P., Andersen, Mads Hald & Svane, Inge Marie, 2011, In: Journal of Skin Cancer. 2011, 574695, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A promiscuous survivin-derived T-cell epitope restricted to the HLA-A3 super-type alleles
Junker, N., Munir, S., Kvistborg, P., Straten, P. T., Svane, Inge Marie & Andersen, M. H., 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2115-2118 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., Buchwald, C. V., Andersen, E., Straten, P. T., Svane, Inge Marie & Andersen, Mads Hald, 24 Mar 2011, In: Cytotherapy. 13, 7, p. 822-34Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures
Junker, N., Kvistborg, P., Køllgaard, T., Straten, P. T., Andersen, Mads Hald & Svane, Inge Marie, 2012, In: Cellular Immunology. 273, 1, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., von Buchwald, Christian, Andersen, E., Straten, P. T. & Svane, Inge Marie, 2011, In: Cytotherapy. 13, 7, p. 822-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide Vaccination Against PD-L1 With IO103 a Novel Immune Modulatory Vaccine in Multiple Myeloma: A Phase I First-in-Human Trial
Jørgensen, N. G., Klausen, U., Grauslund, J. H., Helleberg, C., Aagaard, T. G., Do, T. H., Ahmad, S. M., Olsen, L. R., Klausen, T. W., Breinholt, M. F., Hansen, M., Martinenaite, E., Met, Özcan, Svane, Inge Marie, Knudsen, L. M. & Andersen, Mads Hald, 2020, In: Frontiers in Immunology. 11, 11 p., 595035.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial
Jørgensen, N. G., Ahmad, S. M., Abildgaard, N., Straten, P. T., Svane, Inge Marie, Andersen, Mads Hald & Knudsen, L. M., 2016, In: Stem Cell Investigation. 3, 5 p., 95.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4054758
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Research output: Contribution to journal › Journal article › Research › peer-review
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258
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Research output: Contribution to journal › Journal article › Research › peer-review
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189
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
Research output: Contribution to journal › Journal article › Research › peer-review
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