Indra John Heckenbach

Indra John Heckenbach

Guest Researcher


Publication year:
All
1 - 9 out of 9Page size: 10
  1. 2023
  2. Published

    Deep Learning to Characterize Cellular Senescence in Aging and Age-related Diseases

    Heckenbach, Indra John, 4 Apr 2023, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  3. Published

    CD38 regulates ovarian function and fecundity via NAD+ metabolism

    Perrone, R., Ashok Kumaar, P. V., Haky, L., Hahn, C., Riley, R., Balough, J., Zaza, G., Soygur, B., Hung, K., Prado, L., Kasler, H. G., Tiwari, R., Matsui, H., Hormazabal, G. V., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Duncan, F. E. & Verdin, E., 2023, In: iScience. 26, 10, 27 p., 107949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Histone malonylation is regulated by SIRT5 and KAT2A

    Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Tracking the dynamics of cellular senescence

    Heckenbach, Indra John & Scheibye-Knudsen, Morten, 2023, In: Aging. 15, 9, p. 3219-3220 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  6. 2022
  7. Published

    A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

    Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

    Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., Ding, L., Duncan, F. E., Eickelberg, O., Fan, R., Finkel, T., Furman, D., Garovic, V., Gehlenborg, N., Glass, C., Heckenbach, I., Joseph, Z. B., Katiyar, P. & 48 others, Kim, S. J., Königshoff, M., Kuchel, G. A., Lee, H., Lee, J. H., Ma, J., Ma, Q., Melov, S., Metis, K., Mora, A. L., Musi, N., Neretti, N., Passos, J. F., Rahman, I., Rivera-Mulia, J. C., Robson, P., Rojas, M., Roy, A. L., Scheibye-Knudsen, Morten, Schilling, B., Shi, P., Silverstein, J. C., Suryadevara, V., Xie, J., Wang, J., Wong, A. I., Niedernhofer, L. J., Wang, S., Anvari, H., Balough, J., Stanford TDA, S. T., University of Connecticut TMC, U. O. C. T., University of Michigan TDA, U. O. M. T., University of Minnesota TMC, U. O. M. T., University of Pittsburgh TMC, U. O. P. T., University of Washington TDA, U. O. W. T., Washington University TMC, W. U. T., Yale TMC, Y. T., SenNet Consortium, S. C., Writing Group, W. G., Brown University TDA, B. U. T., Buck Institute for Research on Aging TMC/TDA, B. I. F. R. O. A. T., Consortium Organization and Data Coordinating Center (CODCC), C. O. A. D. C. C. (., Columbia TMC, C. T., Duke University TMC, D. U. T., Massachusetts General Hospital TDA, M. G. H. T., Mayo Clinic TDA, M. C. T. & National Institute of Health (NIH), N. I. O. H. (., 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Nuclear morphology is a deep learning biomarker of cellular senescence

    Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2021
  11. Published

    Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis

    Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, Indra John, Scheibye-Knudsen, Morten, De, S., Sen, P., Abdelmohsen, K. & Gorospe, M., 2021, In: Nucleic Acids Research. 49, 13, p. 7389-7405 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2020
  13. Published

    Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

    Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, Riley, R., Ben-Sahra, I., Ott, M., Schilling, B., Scheibye-Knudsen, Morten, Ishihara, K., Quake, S. R., Newman, J., Brenner, C., Campisi, J. & Verdin, E., 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 203399293