Ida Moltke
Associate Professor
Computational and RNA Biology
Ole Maaløes Vej 5
2200 København N.
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Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moltke, Ida, van Overseem Hansen, T., Nielsen, Finn Cilius & Nielsen, Rasmus, 2009, In: Genetic Epidemiology. 33, 3, p. 266-274Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, , 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of sucrase-isomaltase function increases acetate levels and improves metabolic health in Greenlandic cohorts
Andersen, M. K., Skotte, L., Jørsboe, E., Polito, R., Stæger, F. F., Aldiss, P., Hanghøj, K., Waples, R. K., Santander, C. G., Grarup, N., Dahl-Petersen, I. K., Diaz, L. J., Overvad, M., Senftleber, N. K., Søborg, B., Larsen, C. V. L., Lemoine, C., Pedersen, O., Feenstra, B., Bjerregaard, P. & 9 others, , 2022, In: Gastroenterology. 162, 4, p. 1171-1182.e3Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics of Type 2 diabetes: the power of isolated populations
Lepola, Mette Andersen, Pedersen, C. T., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders & Grarup, Niels, 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, Niels, Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations
Lepola, Mette Andersen, Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, Niels, 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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African bushpigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival
Balboa, R. F., Bertola, L. D., Brüniche-Olsen, A., Rasmussen, M. S., Liu, X., Besnard, G., Salmona, J., Santander, C. G., He, S., Zinner, D., Pedrono, M., Muwanika, V., Masembe, C., Schubert, M., Kuja, J., Quinn, L., Garcia-Erill, G., Stæger, F. F., Rakotoarivony, R., Henrique, M. & 14 others, , 2024, In: Nature Communications. 15, 1, 15 p., 172.Research output: Contribution to journal › Journal article › Research › peer-review
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Giraffe lineages are shaped by major ancient admixture events
Bertola, L. D., Quinn, L., Hanghøj, K., Garcia-Erill, G., Rasmussen, M. S., Balboa, R. F., Meisner, J., Bøggild, T., Wang, X., Lin, L., Nursyifa, C., Liu, X., Li, Z., Chege, M., Moodley, Y., Brüniche-Olsen, A., Kuja, J., Schubert, M., Agaba, M., Santander, C. G. & 7 others, , 2024, In: Current Biology. 34, 7, p. 1576-1586.e5 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A probabilistic model of RNA conformational space
Frellsen, J., Moltke, Ida, Thiim, M., Mardia, K. V., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2009, In: PLoS Computational Biology. 5, 6, p. e1000406Research output: Contribution to journal › Journal article › Research › peer-review
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Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli, M., Moltke, Ida, Grarup, Niels, Racimo, F., Bjerregaard, P., Jørgensen, M. E., Korneliussen, Thorfinn Sand, Gerbault, P., Skotte, L., Linneberg, Allan René, Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E. B., Pedersen, Oluf Borbye, Hansen, T., Albrechtsen, Anders & Nielsen, Rasmus, 2015, In: Science (New York, N.Y.). 349, 6254, p. 1343-1347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits
Gilly, A., Suyeges, D., Kuchenbaecker, K., Pollard, M., Southam, L., Hatzikotoulas, K., Farmaki, A-E., Bjornland, T., Waples, R., Appel, E. V. R., Casalone, E., Melloni, G., Kilian, B., Rayner, N. W., Ntalla, I., Kundu, K., Walter, K., Danesh, J., Butterworth, A., Barroso, I. & 5 others, , 1 Dec 2018, In: Nature Communications. 9, p. 1-9 4674.Research output: Contribution to journal › Journal article › Research › peer-review
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The population genomic legacy of the second plague pandemic
Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, , 2022, In: Current Biology. 32, 21, p. 4743-4751.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Diabetes in population isolates: lessons from Greenland
Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2015, In: The Review of Diabetic Studies. 12, 3-4, p. 320-329 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015Research output: Contribution to journal › Journal article › Research › peer-review
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Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding
Hanghøj, Kristian Ebbesen, Moltke, Ida, Andersen, P. A., Manica, A. & Korneliussen, Thorfinn Sand, May 2019, In: GigaScience. 8, 5, 9 p., giz034.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological and Genetic Adaptations to Diving in Sea Nomads
Ilardo, M. A., Moltke, Ida, Korneliussen, Thorfinn Sand, Cheng, J., Stern, A. J., Racimo, Fernando, Damgaard, P. D. B., Sikora, Martin, Seguin-Orlando, A., Rasmussen, Simon, van den Munckhof, I. C. L., ter Horst, R., Joosten, L. A. B., Netea, M. G., Salingkat, S., Nielsen, Rasmus & Willerslev, Eske, 2018, In: Cell. 173, 3, p. 569-580 12 p., e15.Research output: Contribution to journal › Journal article › Research › peer-review
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An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Jørsboe, E., Andersen, M. K., Skotte, L., Stæger, F. F., Færgeman, N. J., Hanghøj, K., Santander, C. G., Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, M., Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, N., Moltke, I. & 2 others, , 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide scan in affected sib-pairs with idiopathic recurrent miscarriage suggests genetic linkage
Kolte, A. M., Nielsen, Henriette Svarre, Moltke, Ida, Degn, B., Pedersen, B., Sunde, L., Nielsen, Finn Cilius & Christiansen, O. B., 2011, In: Molecular Human Reproduction. 17, 6, p. 379-385 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NgsRelate: a software tool for estimating pairwise relatedness from next-generation sequencing data
Korneliussen, Thorfinn Sand & Moltke, Ida, 2015, In: Bioinformatics (Oxford, England). 31, 24, p. 4009-4011 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen, Thorfinn Sand, Moltke, Ida, Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: B M C Bioinformatics. 14, 14 p., 289.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-resolution map of human evolutionary constraint using 29 mammals
Lindblad-Toh, K., Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Jordan, G., Mauceli, E., Ward, L. D., Lowe, C. B., Holloway, A. K., Clamp, M., Gnerre, S., Moltke, Ida, Wen, J. & Pedersen, J. S., 27 Oct 2011, In: Nature. 478, 7370, p. 476-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations
Liu, X., Lin, L., Sinding, M. H. S., Bertola, L. D., Hanghøj, K., Quinn, L., Garcia-Erill, G., Rasmussen, M. S., Schubert, M., Pečnerová, P., Balboa, R. F., Li, Z., Heaton, M. P., Smith, T. P. L., Pinto, R. R., Wang, X., Kuja, J., Brüniche-Olsen, A., Meisner, J., Santander, C. G. & 8 others, , 2024, In: Nature Communications. 15, 1, 16 p., 2921.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1740946
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True single-molecule DNA sequencing of a pleistocene horse bone
Research output: Contribution to journal › Journal article › Research › peer-review
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3165
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Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data
Research output: Contribution to journal › Journal article › Research › peer-review
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1468
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A probabilistic model of RNA conformational space
Research output: Contribution to journal › Journal article › Research › peer-review
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