Helle S. Waagepetersen

Helle S. Waagepetersen

Guest Researcher

ORCID: 0000-0003-4583-8379

Publication year:
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1 - 100 out of 204Page size: 100
  1. 2003
  2. Published

    Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using DL-threo-beta-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 14 May 2003, In: Neurochemistry International. 43, 4-5, p. 417-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2004
  4. Published

    Role of astrocytes in depolarization-coupled release of glutamate in cerebellar cultures

    Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, Jan 2004, In: Neurochemical Research. 29, 1, p. 257-65 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission

    Schousboe, Arne, Sarup, A., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Larsson, O. M., Sep 2004, In: Neurochemistry International. 45, 4, p. 521-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures

    Bak, Lasse Kristoffer, Sickmann, H. M., Schousboe, Arne & Waagepetersen, Helle S., 4 Dec 2004, In: Journal of Neuroscience Research. 79, 1-2, p. 88-96 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2005
  8. Published

    Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter

    Brown, A. M., Sickmann, H. M., Fosgerau, K., Lund, Trine Meldgaard, Schousboe, Arne, Waagepetersen, Helle S. & Ransom, B. R., 2005, In: Journal of Neuroscience Research. 79, 1-2, p. 74-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2006
  10. Published

    Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools

    Sonnewald, U., Kortner, T. M., Qu, H., Olstad, E., Suñol, C., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 7 Mar 2006, In: Neurochemistry International. 48, 6-7, p. 572-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., Aug 2006, In: Journal of Neurochemistry. 98, 3, p. 641-53 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

    Bak, Lasse Kristoffer, Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Oct 2006, In: Journal of Cerebral Blood Flow and Metabolism. 26, 10, p. 1285-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2007
  14. Published

    Actions of toxins on cerebral metabolism at cellular level

    Sonnewald, U., Syversen, T., Schousboe, Arne, Waagepetersen, Helle S. & Aschner, M., 2007, Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. Lajtha, A., Gibson, G. E. & Dienel, G. A. (eds.). 3rd. ed. ed. Berlin: Springer, Vol. 3. p. 569-585

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  15. Published

    Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure

    Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neuroscience Research. 86, p. 3465-3470

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes

    Bak, Lasse Kristoffer, Waagepetersen, Helle S., Melø, T. M., Schousboe, Arne & Sonnewald, U., 2007, In: Neurochemical Research. 32, p. 671-680

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., 2007, In: Neurotoxicity Research. 12, 4, p. 263-268

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    GABA: Homeostatic and pharmacological aspects

    Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Progress in Brain Research. 160, p. 9-19

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Glutamine in the central nervous system: function and dysfunction

    Albrecht, J., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 2007, In: Frontiers in Bioscience. 12, p. 332-343

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Glutamine, glutamate and GABA: metabolic aspects

    Waagepetersen, Helle S., Sonnerwald, U. & Schousboe, Arne, 2007, Handbook of neurochemistry and molecular neurobiology: amino acids and peptides in the nervous system. Lajtha, A., Oja, S. S., Schousboe, A. & Saransaari, P. (eds.). 3rd. ed. Berlin: Springer, p. 1-21

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  21. Published

    One third of glycolytic activity in astrocytes depends on the operation of the glycogen shunt

    Walls, Anne Byriel, Heimbürger, C. M., Sickmann, H. M., Bouman, S. D., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 119

    Research output: Contribution to journal › Conference abstract in journal › Research

  22. Published

    The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

    Johansen, M. L., Bak, Lasse Kristoffer, Schousboe, Arne, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Gjedde, A., Ott, P. & Waagepetersen, Helle S., 2007, In: Neurochemistry International. 50, p. 1042-1051

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

    Lovatt, D., Sonnewald, U., Waagepetersen, Helle S., Schousboe, Arne, He, W., Lin, J. H., Han, X., Takano, T., Wang, S., Sim, F. J., Goldman, S. A. & Nedergaard, M., 2007, In: Journal of Neuroscience. 27, 45, p. 12255-12266

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity

    Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116

    Research output: Contribution to journal › Conference abstract in journal › Research

  25. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., Dec 2007, In: Neurotoxicity Research. 12, 4, p. 263-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2008
  27. Published

    Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

    Walls, Anne Byriel, Sickmann, H. M., Brown, A., Bouman, S. D., Ransom, B., Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Journal of Neurochemistry. 105, p. 1462-1470

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    GABA Neurotransmission: An overview

    Schousboe, Arne & Waagepetersen, Helle S., 2008, Handbook of Neurochemistry and Molecular Neurobiology: Neurotransmitter Systems. Vizi, E. S. (ed.). The Netherlands: Springer Publishing Company, p. 213-226

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  30. Published

    Is neuronal utilization of glucose and lactate linked to Ca2+-dependent modulation of malate-aspartate shuttle activity?

    Waagepetersen, Helle S., Bak, Lasse Kristoffer, Walls, Anne Byriel & Schousboe, Arne, 2008.

    Research output: Contribution to conference › Poster › Research

  31. Published

    Metabolism of [1,6-13C]glucose and [U-13C]glutamine and depolarization induced GABA release in superfused mouse cerebral cortical mini-slices

    Waagepetersen, Helle S., Døring, S. & Schousboe, Arne, 2008, In: Neurochemical Research. 33, 8, p. 1610-1617

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix

    Bak, Lasse Kristoffer, Zieminska, E., Waagepetersen, Helle S., Schousboe, Arne & Albrecht, J., 2008, In: Neurochemical Research. 33, 2, p. 273-278

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The micro-architecture of the cerebral cortex: Functional neuroimaging models and metabolism

    Riera, J. J., Schousboe, Arne, Waagepetersen, Helle S., Howarth, C. & Hyder, F., 2008, In: NeuroImage. 40, 4, p. 1436-1459

    Research output: Contribution to journal › Review › Research

  34. 2009
  35. Published

    Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate

    Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291

    Research output: Contribution to journal › Conference abstract in journal › Research

  36. Published

    Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons

    Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Characterisation of in-vitro blood-brain barrier models

    Helms, H. C., Eriksson, A. H., Waagepetersen, Helle S. & Larsen, Birger Brodin, 2009.

    Research output: Contribution to conference › Poster › Research

  38. Published

    Functional significance of brain glycogen in sustaining glutamatergic neurotransmission

    Sickmann, H. M., Walls, Anne Byriel, Schousboe, Arne, Bouman, S. D. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 80-86 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    GABA synthesis from ß-hydroxybutyrate and glucose is differentially affected by neuronal activity in cultured GABAergic neurons

    Lund, Trine Meldgaard, Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s2, p. 95

    Research output: Contribution to journal › Conference abstract in journal › Research

  40. Published

    GAD65 is essential for the maintenance of GABA homeostasis

    Smeland, O., Walls, A. B., Eyolfsson, E. M., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2009, In: Journal of Neurochemistry. p. 51-51

    Research output: Contribution to journal › Conference abstract in journal › Research

  41. Published

    GAD65 is essential for the maintenance of GABA homeostasis

    Walls, A. B., Eyolfsson, E. M., Sonnewald, U., Vestergaard, H. T., Hansen, S. L., Schousboe, I. E., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 292-292

    Research output: Contribution to journal › Conference abstract in journal › Research

  42. Published

    Gamma-aminobutyric acid (GABA)

    Schousboe, Arne & Waagepetersen, Helle S., 2009, Encyclopedia of neuroscience. Squire, L. R. (ed.). Academic Press, Vol. 4. p. 511-515

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  43. Published

    Glial glutamate and GABA metabolism    

    Waagepetersen, Helle S. & Schousboe, Arne, 2009, Encyclopedia of neuroscience. Squire, L. R. (ed.). Academic Press, Vol. 4. p. 789-792

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  44. Published

    Impact of the malate-aspartate shuttle in glutamate neurotransmission

    Waagepetersen, Helle S., Bak, Lasse Kristoffer, Lund, Trine Meldgaard, Walls, A. B., Sonnewald, U. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. s1, p. 9

    Research output: Contribution to journal › Conference abstract in journal › Research

  45. Published

    Knockdown of GDH indicates its potential impact in sustaining glutamate homeostasis and neurotransmission

    Klawonn, A. M., Bolanos, J. P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. s2, p. 105

    Research output: Contribution to journal › Conference abstract in journal › Research

  46. Published

    Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy

    Iversen, P., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Vafaee, M. S., Borghammer, P., Mouridsen, K., Jensen, S. B., Vilstrup, H., Schousboe, Arne, Ott, P., Gjedde, Albert & Keiding, S., 2009, In: Gastroenterology. 136, 3, p. 863-871

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia

    Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Metabolic Brain Disease. 24, 1, p. 135-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Metabolic profiles of the brains of Zucker Diabetic Fatty, Zucker Obese and Sprague-Dawley rats and the involvement of glycogen metabolism

    Sickmann, H. M., Bouman, S. D., Schousboe, Arne, Tracey, W. R. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 293-293

    Research output: Contribution to journal › Conference abstract in journal › Research

  49. Published

    Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels

    Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne, Ring, A., Sonnewald, U. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 87-93 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Neuronal metabolism in GAD65 knockout mice is compromised and not susceptible to kainic acid

    Walls, A. B., Eyjolfsson, E. M., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. Suppl. 2, p. 123

    Research output: Contribution to journal › Conference abstract in journal › Research

  51. Published

    Prenatal stress effect on glutamate metabolism, evaluated with mass espectroscopy-liquid cromatography

    Adrover, E., Katunar, M. R., Waagepetersen, Helle S., Schousboe, Arne & Antonelli, M. C., 2009, In: Journal of Neurochemistry. Suppl. 2, p. 172-172

    Research output: Contribution to journal › Conference abstract in journal › Research

  52. Published

    Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy

    Keiding, S., Iversen, P., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Gjedde, A., Schousboe, Arne & Vilstrup, H., 2009, In: Journal of Neurochemistry. s1, p. 269-270

    Research output: Contribution to journal › Conference abstract in journal › Research

  53. Published

    Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents

    Walls, Anne Byriel, Heimbürger, C., Bouman, S., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Neuroscience. 158, 1, p. 284-292

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    In vitro blood-brain barrier models

    Helms, H. C. C., Eriksson, A. H., Nielsen, C. U., Waagepetersen, Helle S. & Larsen, Birger Brodin, 18 Jul 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  55. Published

    Characterization of in-vitro blood-brain barrier models

    Helms, H. C. C., Eriksson, A. H., Nielsen, C. U., Waagepetersen, Helle S. & Larsen, Birger Brodin, Aug 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  56. Published

    Characterization of in vitro blood-brain barrier models

    Helms, H. C. C., Eriksson, A. H., Nielsen, C. U., Waagepetersen, Helle S., Walls, Anne Byriel & Larsen, Birger Brodin, 9 Aug 2009. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  57. Published

    Erratum: Demonstration of neuron-glia transfer of precursors for gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex (Neurochem Res (2008) 33:26292635;DOI 10.1007/s11064-008-9814-6)

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 1 Dec 2009, In: Neurochemical Research. 34, 12, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  58. 2010
  59. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. s1, p. 288-289

    Research output: Contribution to journal › Conference abstract in journal › Research

  60. Published

    Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex

    Jensen, Dorte Skytt, Madsen, K. K., Pajecka, K., Schousboe, Arne & Waagepetersen, Helle S., 2010, In: Neurochemical Research. 35, 12, p. 2043-2052 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Claudin-5 mRNA expression and transendothelial electrical resistance (TEER) correlate in the BCEC/astrocyte blood-brain barrier model

    Helms, H. C. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2010. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  62. Published

    Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient

    Schousboe, Arne, Sickmann, H. M., Walls, Anne Byriel, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 2010, In: Neurotoxicity Research. 18, 1, p. 94-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    GABA-syntese - en vigtig brik for kontrol af epilepsi

    Walls, Anne Byriel, Schousboe, Arne & Waagepetersen, Helle S., 2010, In: Lægemiddelforskning. 2010, p. 31-33

    Research output: Contribution to journal › Journal article › Communication

  64. Published

    GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity

    Walls, Anne Byriel, Nilsen, L. H., Eyjolfsson, E. M., Vestergaard, H. T., Hansen, S. L., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. 115, 6, p. 1398–1408

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Glial cell biology: neuronal-glial interaction in nutrition and amino-acid-mediated neurotransmission

    Schousboe, Arne & Waagepetersen, Helle S., 2010, The newborn brain: Neuroscience and clinical applications. Lagercrantz, H., Hanson, M. A., Ment, L. R. & Peebles, D. M. (eds.). 2 ed. Cambridge: Cambridge University Press, p. 121-128

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  66. Published

    Hjernens forsvarsmur kortlagt og kopieret

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2010, In: Lægemiddelforskning. 2010, p. 22-24

    Research output: Contribution to journal › Journal article › Communication

  67. Published

    Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis

    Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 8, p. 1527-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    The expression of Claudin-5 correlates with transendothelial electrical resistance (TEER) in BCEC/rat astrocyte blood-brain barrier models

    Helms, H. C. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2010.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  69. Published

    A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures

    Suñol, C., Babot, Z., Cristòfol, R., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, Sep 2010, In: Neurochemical Research. 35, 9, p. 1384-1390 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Paracellular tightness and claudin-5 expression is increased in the BCEC/Astrocyte blood-brain barrier model by increasing media buffer capacity during growth

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, Dec 2010, In: The AAPS Journal. 12, 4, p. 759-770

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. 2011
  72. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2011, Functional molecular imaging in hepatology. Bussum, The Netherlands: Bentham Science Publishers, p. 129-144

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  73. Published

    Glutamate and glutamine in brain disorders

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2011, Neurochemical mechanisms in diseases. Blass, J. P. (ed.). New York: Springer Publishing Company, Vol. 1. p. 195-212 (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  74. Published

    Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine

    Walls, Anne Byriel, Eyjolfsson, E. M., Smeland, O. B., Nilsen, L. H., Schousboe, I., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 494-503 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    13C NMR spectroscopy and mass spectrometry analysis of intermediary metabolism in cultured neural cells

    Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 18 Mar 2011, Cell Culture Techniques. Aschner, M., Sunol, C. & Bal-Price, A. (eds.). p. 403-415 13 p. (Neuromethods, Vol. 56).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  76. Published

    Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

    Leke, R., Bak, Lasse Kristoffer, Anker, M., Melø, T. M., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Apr 2011, In: Neurotoxicity Research. 19, 3, p. 496-510 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In: Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Jajo, F. S., Faek, S. A. A. & Waagepetersen, Helle S., 1 Dec 2011, In: Journal of Neuroscience Research. 89, 12, p. 1926-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. 2012
  82. Published

    Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

    Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.

    Research output: Contribution to journal › Review › Research › peer-review

  83. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  84. Published

    Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model

    Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2012, In: Neurochemistry International. 60, 3, p. 267-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission

    Frigerio, F., Karaca, M., De Roo, M., Mlynarik, V., Jensen, Dorte Skytt, Carobbio, S., Pajecka, K., Waagepetersen, Helle S., Gruetter, R., Muller, D. & Maechler, P., 2012, In: Journal of Neurochemistry. 123, 3, p. 342-348

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Delineation of glutamate pathways and secretory responses in pancreatic islets with ß-cell-specific abrogation of the glutamate dehydrogenase.

    Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation

    Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity

    Obel, L. L. F., Andersen, K. M. H., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurotoxicity Research. 21, 4, p. 405-17 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Glutamate efflux from brain to blood - Studies in an in vitro blood-brain barrier model

    Helms, H. C. C., Madelung, R., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2012.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  90. Published

    Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats

    Leke, R., de Oliveira, D. L., Mussulini, B. H. M., Pereira, M. S., Kazlauckas, V., Mazzini, G., Hartmann, C. R., Silveira, T. R., Simonsen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Keiding, S., Schousboe, Arne & Portela, L. V., 2012, In: P L o S One. 7, 5, p. e36322

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate

    Helms, H. C., Madelung, R., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2012, In: Glia. 60, 6, p. 882-893

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    In-vitro models of the blood brain barrier

    Larsen, Birger Brodin, Helms, H. C. C., Groth, S., Waagepetersen, Helle S. & Nielsen, C. U., 2012. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  93. Published

    Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons

    Bak, Lasse Kristoffer, Obel, L. L. F., Walls, Anne Byriel, Schousboe, Arne, Faek, S. A. A., Jajo, F. S. & Waagepetersen, Helle S., 2012, In: A S N Neuro. 4, 3, p. 151-160

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Quantitative importance of the pentose phosphate pathway determined by incorporation of 13C from [2-13C]- and [3-13C]glucose into TCA cycle intermediates and neurotransmitter amino acids in functionally intact neurons

    Brekke, E. M., Walls, Anne Byriel, Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 9, p. 1788-1799 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons

    Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Journal of Neuroscience Research. 90, 9, p. 1768-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate

    Jensen, Dorte Skytt, Klawonn, A. M., Strid, M. H., Pajecka, K., Patruss, Y., Quintana-Cabrera, R., Bolanos, J. P., Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurochemistry International. 61, 4, p. 490-497

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level

    Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  98. Published

    Importance of glutamate dehydrogenase, GDH, in astrocyte metabolism for maintenance of glutamate and energy homeostasis

    Waagepetersen, Helle S., 29 Jun 2012, København. 66 p.

    Research output: Book/Report › Ph.D. thesis › Research

  99. Published

    In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells co-cultured with astrocytes display a polarized brain-to-blood transport of glutamate

    Helms, H. C. C., Madelung, R., Groth, S., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 13 Sep 2012. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  100. Published

    Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase

    Vetterli, L., Carobbio, S., Pournourmohammadi, S., Martin-Del-Rio, R., Jensen, Dorte Skytt, Waagepetersen, Helle S., Tamarit-Rodriguez, J. & Maechler, P., Oct 2012, In: Molecular Biology of the Cell. 23, 19, p. 3851-62 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission

    Frigerio, F., Karaca, M., De Roo, M., Mlynárik, V., Jensen, Dorte Skytt, Carobbio, S., Pajęcka, K., Waagepetersen, Helle S., Gruetter, R., Muller, D. & Maechler, P., Nov 2012, In: Journal of Neurochemistry. 123, 3, p. 342-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Primary cultures of astrocytes: their value in understanding astrocytes in health and disease

    Lange, S. C., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Nov 2012, In: Neurochemical Research. 37, 11, p. 2569-88 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Energy Metabolism of the Brain

    McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  104. 2013
  105. Published

    Amino acid neurotransmitter synthesis and removal

    Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  106. Published

    Cellemodel af blodhjernebarrieren kan mindske brugen af forsøgsdyr

    Larsen, Birger Brodin, Helms, H. C. C., Hersom, M. N. S., Nielsen, C. U. & Waagepetersen, Helle S., 2013, In: Lægemiddelforskning. 2013, p. 47-49 3 p.

    Research output: Contribution to journal › Journal article › Communication

  107. Published

    Interorgan metabolism of ornithine phenylacetate (OP)-A novel strategy for treatment of hyperammonemia

    Dadsetan, S., Sørensen, M., Bak, Lasse Kristoffer, Vilstrup, H., Ott, P., Schousboe, Arne, Jalan, R., Keiding, S. & Waagepetersen, Helle S., 2013, In: Biochemical Pharmacology. 85, 1, p. 115-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Reply to letter to the editor by Zheng G et al. Venous blood ammonia can be associated with cerebral blood flow in hepatic encephalopathy

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., 2013, In: Hepatology. 58, 2, p. 833-834

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  109. Published

    Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Sørensen, M., Jan 2013, In: Hepatology. 57, 1, p. 258-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Glutamate dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization

    Pajecka, K., Nielsen, C. W., Hauge, A., Zaganas, I., Bak, Lasse Kristoffer, Schousboe, Arne, Plaitakis, A. & Waagepetersen, Helle S., 26 Apr 2013, In: Neurochemical Research. 39, 3, p. 487-499

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Excitatory amino acid transporter-1 (EAAT1) is the main transporter responsible for abluminal uptake of L-glutamate in bovine brain endothelial cells

    Helms, H. C. C., Groth, S., Mikél, M., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 27 May 2013.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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