Graham John Belsham

Graham John Belsham

Professor


  1. 2007
  2. Published

    Significance of arginine 20 in the 2A protease for swine vesicular disease virus pathogenicity

    Inoue, T., Zhang, Z., Wang, L., West, L., Bashiruddin, J. B. & Belsham, Graham John, Aug 2007, In: The Journal of general virology. 88, Pt 8, p. 2275-2279 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification of minimal sequences of the Rhopalosiphum padi virus 5' untranslated region required for internal initiation of protein synthesis in mammalian, plant and insect translation systems

    Groppelli, E., Belsham, Graham John & Roberts, L. O., May 2007, In: The Journal of general virology. 88, Pt 5, p. 1583-1588 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inhibition of the secretory pathway by foot-and-mouth disease virus 2BC protein is reproduced by coexpression of 2B with 2C, and the site of inhibition is determined by the subcellular location of 2C

    Moffat, K., Knox, C., Howell, G., Clark, S. J., Yang, H., Belsham, Graham John, Ryan, M. & Wileman, T., Feb 2007, In: Journal of Virology. 81, 3, p. 1129-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2006
  6. Published

    Role of RNA structure and RNA binding activity of foot-and-mouth disease virus 3C protein in VPg uridylylation and virus replication

    Nayak, A., Goodfellow, I. G., Woolaway, K. E., Birtley, J., Curry, S. & Belsham, Graham John, Oct 2006, In: Journal of Virology. 80, 19, p. 9865-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Caliciviruses differ in their functional requirements for eIF4F components

    Chaudhry, Y., Nayak, A., Bordeleau, M., Tanaka, J., Pelletier, J., Belsham, Graham John, Roberts, L. O. & Goodfellow, I. G., 1 Sep 2006, In: The Journal of Biological Chemistry. 281, 35, p. 25315-25 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A

    Bordeleau, M., Mori, A., Oberer, M., Lindqvist, L., Chard, L. S., Higa, T., Belsham, Graham John, Wagner, G., Tanaka, J. & Pelletier, J., Apr 2006, In: Nature Chemical Biology. 2, 4, p. 213-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Functional analyses of RNA structures shared between the internal ribosome entry sites of hepatitis C virus and the picornavirus porcine teschovirus 1 talfan

    Chard, L. S., Kaku, Y., Jones, B., Nayak, A. & Belsham, Graham John, 2006, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Hepatitis C virus-related internal ribosome entry sites are found in multiple genera of the family Picornaviridae

    Chard, L. S., Bordeleau, M., Pelletier, J., Tanaka, J. & Belsham, Graham John, 2006, In: Journal of General Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Stabilized baculovirus vector expressing a heterologous gene and GP64 from a single bicistronic transcript

    Pijlman, G. P., Roode, E. C., Fan, X., Roberts, L. O., Belsham, Graham John, Vlak, J. M. & van Oers, M. M., 2006, In: Journal of Biotechnology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2005
  13. Published

    Importance of arginine 20 of the swine vesicular disease virus 2A protease for activity and virulence

    Inoue, T., Alexandersen, S., Clark, A. T., Murphy, C., Quan, M., Reid, S. M., Sakoda, Y., Johns, H. L. & Belsham, Graham John, Jan 2005, In: Journal of Virology. 79, 1, p. 428-440 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A cross-Kingdom internal ribosome entry site reveals a simplified mode of internal ribosome entry

    Terenin, I. M., Dmitriev, S. E., Andreev, D. E., Royall, E., Belsham, Graham John, Roberts, L. O. & Shatsky, I. N., 2005, In: Molecular and Cellular Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Effects of foot-and-mouth disease virus nonstructural proteins on the structure and function of the early secretory pathway: 2BC but not 3A blocks endoplasmic reticulum-to-Golgi transport

    Moffat, K., Howell, G., Knox, C., Belsham, Graham John, Monaghan, P., Ryan, M. D. & Wileman, T., 2005, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Factors required for the uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3D pol) in vitro

    Nayak, A., Goodfellow, I. G. & Belsham, Graham John, 2005, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Translation and replication of FMDV RNA

    Belsham, Graham John, 2005, In: Current Topics in Microbiology and Immunology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2004
  19. Published
  20. Published

    Genome Organisation, Translation and Replication of Foot-and-Mouth Disease Virus RNA

    Martinez-Salas, E. & Belsham, Graham John, Aug 2004

    Research output: Other contributionResearch

  21. Published

    The Rhopalosiphum padi virus 5′ internal ribosome entry site is functional in Spodoptera frugiperda 21 cells and in their cell-free lysates: Implications for the baculovirus expression system

    Royall, E., Woolaway, K. E., Schacherl, J., Kubick, S., Belsham, Graham John & Roberts, L. O., Jun 2004, In: Journal of General Virology. 85, 6, p. 1565-1569 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Functional and Structural Similarities between the Internal Ribosome Entry Sites of Hepatitis C Virus and Porcine Teschovirus, a Picornavirus

    Pisarev, A. V., Chard, L. S., Kaku, Y., Johns, H. L., Shatsky, I. N. & Belsham, Graham John, May 2004, In: Journal of Virology. 78, 9, p. 4487-4497 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cleavage of Eukaryotic Translation Initiation Factor 4GII within Foot-and-Mouth Disease Virus-Infected Cells: Identification of the L-Protease Cleavage Site in Vitro

    Gradi, A., Foeger, N., Strong, R., Svitkin, Y. V., Sonenberg, N., Skern, T. & Belsham, Graham John, 2004, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. 2003
  26. Published

    Conserved Nucleotides within the J Domain of the Encephalomyocarditis Virus Internal Ribosome Entry Site Are Required for Activity and for Interaction with eIF4G

    Clark, A. T., Robertson, M. E. M., Conn, G. L. & Belsham, Graham John, Dec 2003, In: Journal of Virology. 77, 23, p. 12441-12449 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The Foot-and-Mouth Disease Virus cis-Acting Replication Element (cre) Can Be Complemented in trans within Infected Cells

    Tiley, L., King, A. M. Q. & Belsham, Graham John, 1 Feb 2003, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Rinderpest virus lineage differentiation using RT-PCR and SNAP-ELISA

    Forsyth, M. A., Parida, S., Alexandersen, S., Belsham, Graham John & Barrett, T., Jan 2003, In: Journal of Virological Methods.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2002
  30. Published

    Conservation of L and 3C proteinase activities across distantly related aphthoviruses

    Hinton, T. M., Ross-Smith, N., Warner, S., Belsham, Graham John & Crabb, B. S., 1 Dec 2002, In: Journal of General Virology. 83, 12, p. 3111-3121 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Unique characteristics of a picornavirus internal ribosome entry site from the porcine teschovirus-1 Talfan

    Kaku, Y., Chard, L. S., Inoue, T. & Belsham, Graham John, Nov 2002, In: Journal of Virology. 76, 22, p. 11721-11728 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Detection of all seven serotypes of foot-and-mouth disease virus by real-time, fluorogenic reverse transcription polymerase chain reaction assay

    Reid, S. M., Ferris, N. P., Hutchings, G. H., Zhang, Z., Belsham, Graham John & Alexandersen, S., Aug 2002, In: Journal of Virological Methods.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2001
  34. Published

    Cleavage of translation initiation factor 4AI (eIF4AI) but not eIF4AII by foot-and-mouth disease virus 3C protease: identification of the eIF4AI cleavage site

    Li, W., Ross-Smith, N., Proud, C. G. & Belsham, Graham John, 2 Oct 2001, In: FEBS Letters.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    A novel protein-RNA binding assay: Functional interactions of the foot-and-mouth disease virus internal ribosome entry site with cellular proteins

    Stassinopoulos, I. A. & Belsham, Graham John, 2001, In: RNA.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    An attenuating mutation in the 2A protease of swine vesicular disease virus, a picornavirus, regulates cap- and internal ribosome entry site-dependent protein synthesis

    Sakoda, Y., Ross-Smith, N., Inoue, T. & Belsham, Graham John, 2001, In: Journal of Virology. 75, 22, p. 10643-10650 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Diagnosis of foot-and-mouth disease by real-time fluorogenic PCR assay

    Reid, S. M., Ferris, N. P., Hutchings, G. H., Zhang, Z., Belsham, Graham John & Alexandersen, S., 2001, In: Veterinary Record.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Eukaryotic Initiation Factors 4A (eIF4A) and 4G (eIF4G) Mutually Interact in a 1:1 Ratio in Vivo

    Li, W., Belsham, Graham John & Proud, C. G., 2001, In: Journal of Biological Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Induction of a protective response in swine vaccinated with DNA encoding foot-and-mouth disease virus empty capsid proteins and the 3D RNA polymerase

    Cedillo-Barrón, L., Foster-Cuevas, M., Belsham, Graham John, Lefèvre, F. & Parkhouse, R. M. E., 2001, In: Journal of General Virology. 82, 7, p. 1713-1724 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The 5′ untranslated region of Rhopalosiphum padi virus contains an internal ribosome entry site which functions efficiently in mammalian, plant, and insect translation systems

    Woolaway, K. E., Lazaridis, K., Belsham, Graham John, Carter, M. J. & Roberts, L. O., 2001, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2000
  42. Published

    ABC50 interacts with eukaryotic initiation factor 2 and associates with the ribosome in an ATP-dependent manner.

    Tyzack, J., Wang, X., Belsham, Graham John & Proud, C., Nov 2000, In: The Journal of Biological Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Erratum: Picomavirus RNA translation: Roles for cellular proteins (Trends in Microbiology; July (332))

    Belsham, Graham John & Sonenberg, N., 1 Oct 2000, In: Trends in Microbiology. 8, 10, p. 472 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  44. Published

    Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment.

    Stoneley, M., Subkhankulova, T., Le, Q. J., Coldwell, M., Jopling, C., Belsham, Graham John & Willis, A., Feb 2000, In: Nucleic Acids Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Caspases are not involved in the cleavage of translation initiation factor eIF4GI during picornavirus infection

    Roberts, L. O., Boxall, A. J., Lewis, L. J., Belsham, Graham John & Kass, G. E. N., 2000, In: Journal of General Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Development of reverse transcription-PCR (oligonucleotide probing) enzyme-linked immunosorbent assays for diagnosis and preliminary typing of foot-and-mouth disease: A new system using simple and aqueous-phase hybridization

    Alexandersen, S., Forsyth, M. A., Reid, S. M. & Belsham, Graham John, 2000, In: Journal of clinical microbiology. 38, 12, p. 4604-4613 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cells

    Belsham, Graham John, McInerney, G. M. & Ross-Smith, N., 2000, In: Journal of Virology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Picornavirus RNA translation: Roles for cellular proteins

    Belsham, Graham John & Sonenberg, N., 2000, In: Trends in Microbiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Replication-competent foot-and-mouth disease virus RNAs lacking capsid coding sequences

    McInerney, G. M., King, A. M. Q., Ross-Smith, N. & Belsham, Graham John, 2000, In: Journal of General Virology. 81, 7, p. 1699-1702 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 1999
  51. Published

    Localization of foot-and-mouth disease virus RNA by in situ hybridization within bovine tissues

    Prato Murphy, M. L., Forsyth, M. A., Belsham, Graham John & Salt, J. S., Jul 1999, In: Virus Research. 62, 1, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A selection system for functional internal ribosome entry site (IRES) elements: Analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES

    Robertson, M. E. M., Seamons, R. A. & Belsham, Graham John, 1999, In: RNA.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 1998
  54. Published

    Vaccinia virus protein synthesis has a low requirement for the intact translation initiation factor eIF4F, the cap-binding complex, within infected cells

    Mulder, J., Robertson, M. E. M., Seamons, R. A. & Belsham, Graham John, Nov 1998, In: Journal of Virology. 72, 11, p. 8813-8819 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Differentiating infection from vaccination in foot-and-mouth disease using a panel of recombinant, non-structural proteins in ELISA

    Mackay, Duncan John, Forsyth, M. A., Davies, P. R., Berlinzani, A., Belsham, Graham John, Flint, M. & Ryan, M. D., Mar 1998, In: Vaccine. 16, 5, p. 446-459 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 1997
  57. Published

    Complementation of defective picornavirus internal ribosome entry site (IRES) elements by the coexpression of fragments of the IRES

    Roberts, L. O. & Belsham, Graham John, 6 Jan 1997, In: Virology. 227, 1, p. 53-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The La autoantigen contains a dimerization domain that is essential for enhancing translation.

    Craig, A., Svitkin, Y., Lee, H., Belsham, Graham John & Sonenberg, N., Jan 1997, In: Molecular and Cellular Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 1996
  60. Published

    RNA-protein interactions in regulation of picornavirus RNA translation

    Belsham, Graham John & Sonenberg, N., Sep 1996, In: Microbiological Reviews. 60, 3, p. 499-511 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  61. Published

    Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus

    Gingras, A., Svitkin, Y., Belsham, Graham John, Pause, A. & Sonenberg, N., 1996, In: Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. 1995
  63. Published

    Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans

    Velden, A. V. D., Kaminski, A., Jackson, R. J. & Belsham, Graham John, 1 Dec 1995, In: Virology. 214, 1, p. 82-90 9 p., 79952.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 223344837