Christian Adam Olsen

Christian Adam Olsen

Professor

Member of:


    1. 2022
    2. Published

      Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**

      Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, Tobias Nørby, Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.

      Research output: Contribution to journalJournal articlepeer-review

    3. Published

      Chiral Posttranslational Modification to Lysine ε-Amino Groups

      Moreno Yruela, Carlos, Baek, M., Monda, F. & Olsen, Christian Adam, 2022, In: Accounts of Chemical Research. 55, 10, p. 1456-1466

      Research output: Contribution to journalReviewpeer-review

    4. Published

      Class I histone deacetylases (HDAC1-3) are histone lysine delactylases

      Moreno Yruela, Carlos, Zhang, D., Wei, W., Bæk, M., Liu, W., Gao, J., Dankova, Daniela, Nielsen, A. L., Bolding, J. E., Yang, L., Jameson, S. T., Wong, J., Olsen, Christian Adam & Zhao, Y., 2022, In: Science Advances. 8, 3, eabi6696.

      Research output: Contribution to journalJournal articlepeer-review

    5. Published

      Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity

      Moreno Yruela, Carlos & Olsen, Christian Adam, 2022, In: ACS Medicinal Chemistry Letters. 13, 5, p. 779-785

      Research output: Contribution to journalJournal articlepeer-review

    6. Published

      Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

      Rajabi, N., Hansen, Tobias Nørby, Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, J. E., Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

      Research output: Contribution to journalJournal articlepeer-review

    7. Published

      On-Resin Peptide Cyclization Using the 3-Amino-4-(Methylamino)Benzoic Acid MeDbz Linker

      Gless, B. H. & Olsen, Christian Adam, 2022, Methods in Molecular Biology. Humana Press, p. 101-115 (Methods in Molecular Biology, Vol. 2371).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    8. 2021
    9. Published

      Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases

      Moreno Yruela, Carlos, Bæk, M., Vrsanova, A., Schulte, C., Maric, H. M. & Olsen, Christian Adam, 4 Jan 2021, In: Nature Communications. 12, 1

      Research output: Contribution to journalJournal articlepeer-review

    10. Published

      High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays

      Moreno Yruela, Carlos & Olsen, Christian Adam, 2021, In: STAR Protocols. 2, 1, 14 p., 100313.

      Research output: Contribution to journalJournal articlepeer-review

    11. Published

      Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

      Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

      Research output: Contribution to journalJournal articlepeer-review

    12. Published

      Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

      Troelsen, K. S., Bæk, M., Nielsen, A. L., Madsen, A. S., Rajabi, N. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 627-635

      Research output: Contribution to journalJournal articlepeer-review

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    ID: 101364066