Carsten Niemann
Clinical Associate Professor
Department of Clinical Medicine
Blegdamsvej 9, 2100 København Ø
Member of:
Internal Medicine: Haematology
- Published
Ibrutinib and venetoclax for first-line treatment of CLL
Kater, A. P., Levin, M. D. & Niemann, Carsten, 2019, In: New England Journal of Medicine. 381, 8, p. 788-789 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Ibrutinib sensitizes CLL cells to venetoclax by interrupting TLR9-induced CD40 upregulation and protein translation
Kielbassa, K., Haselager, M. V., Bax, D. J. C., van Driel, B. F., Dubois, J., Levin, M. D., Kersting, S., Svanberg, R., Niemann, Carsten, Kater, A. P. & Eldering, E., 2023, In: Leukemia. 37, 6, p. 1268-1276 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV
Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.Research output: Contribution to journal › Journal article › Research › peer-review
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An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma
Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years
Kolstad, A., Pedersen, L. B., Eskelund, C. W., Husby, S., Grønbæk, K., Jerkeman, M., Laurell, A., Räty, R., Elonen, E., Andersen, N. S., Brown, P. D. N., Kimby, E., Bentzen, H., Sundström, C., Ehinger, M., Karjalainen-Lindsberg, M. L., Delabie, J., Ralfkiær, E., Fagerli, U. M., Nilsson-Ehle, H. & 5 others, , Mar 2017, In: Biology of Blood and Marrow Transplantation. 23, 3, p. 428-435 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low mortality from COVID-19 infection in patients with B-cell lymphoma after bispecific CD20xCD3 therapy
Kyvsgaard, Emil Ramsø, Riley, C., Clausen, M. R., Harsløf, Mads, Heftdal, Line Dam, Niemann, Carsten, Grønbæk, Kirsten, Hutchings, M. & Husby, Simon, 2024, In: British Journal of Haematology. 204, 1, p. 356-360 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Serum proteome modulations upon treatment provides biological insight on response to treatment in relapsed mantle cell lymphoma
Lokhande, L., Kuci Emruli, V., Eskelund, C. W., Kolstad, A., Hutchings, M., Räty, R., Niemann, Carsten, Grønbæk, Kirsten, Jerkeman, M. & Ek, S., 2022, In: Cancer Reports. 5, 8 p., e1524.Research output: Contribution to journal › Journal article › Research › peer-review
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Systematic Literature Review of Economic Evaluations of Treatment Alternatives in Chronic Lymphocytic Leukemia
Lorenzovici, L., Szilberhorn, L., Farkas-Ráduly, S., Gasparik, A. I., Precup, A. M., Nagy, A. G., Niemann, Carsten, Aittokallio, T., Kaló, Z. & Csanádi, M., 2023, In: BioDrugs. 37, 2, p. 219-233 15 p.Research output: Contribution to journal › Review › Research › peer-review
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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia - Update on methodological approaches and results interpretation
Malcikova, J., Tausch, E., Rossi, D., Sutton, L. A., Soussi, T., Zenz, T., Kater, A. P., Niemann, Carsten, Gonzalez, D., Davi, F., Gonzalez Diaz, M., Moreno, C., Gaidano, G., Stamatopoulos, K., Rosenquist, R., Stilgenbauer, S., Ghia, P. & Pospisilova, S., 1 May 2018, In: Leukemia. 32, 5, p. 1070-1080Research output: Contribution to journal › Review › Research › peer-review
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Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Mansouri, L., Thorvaldsdottir, B., Sutton, L. A., Karakatsoulis, G., Meggendorfer, M., Parker, H., Nadeu, F., Brieghel, C., Laidou, S., Moia, R., Rossi, D., Catherwood, M., Kotaskova, J., Delgado, J., Rodríguez-Vicente, A. E., Benito, R., Rigolin, G. M., Bonfiglio, S., Scarfo, L., Mattsson, M. & 41 others, , 2023, In: Leukemia. 37, 2, p. 339-347 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Readmissions, Postdischarge Mortality, and Sustained Recovery Among Patients Admitted to Hospital With Coronavirus Disease 2019 (COVID-19)
Moestrup, K. S., Reekie, J., Zucco, Adrian G., Jensen, T. Ø., Jensen , Jens-Ulrik Stæhr , Wiese, L., Ostrowski, Sisse Rye, Niemann, Carsten, MacPherson, C. R., Lundgren, Jens & Helleberg, Marie, 8 Feb 2023, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 76, 3, p. e82-e89 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CLL-106 First Prospective Data on Minimal Residual Disease Outcomes After Fixed-Duration Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for First-Line Treatment of CLL in Older Adult or Unfit Patients: The GLOW Study
Munir, T., Moreno, C., Owen, C., Follows, G., Benjamini, O., Janssens, A., Levin, M. D., Osterborg, A., Robak, T., Simkovic, M., Stevens, D., Voloshin, S., Vorobyev, V., Yagci, M., Ysebaert, L., Qi, Q., Steele, A., Schuier, N., Baeten, K., Caces, D. B. & 2 others, , 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S264-S265Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Impact of Minimal Residual Disease on Progression-Free Survival Outcomes after Fixed-Duration Ibrutinib-Venetoclax Versus Chlorambucil-Obinutuzumab in the GLOW Study
Munir, T., Moreno, C., Owen, C., Follows, G., Benjamini, O., Janssens, A., Levin, M. D., Osterborg, A., Robak, T., Simkovic, M., Stevens, D., Voloshin, S., Vorobyev, V., Yagci, M., Ysebaert, L., Qi, K., Qi, Q., Parisi, L., Srinivasan, S., Schuier, N. & 5 others, , 2023, In: Journal of Clinical Oncology. 41, 21, p. 3689-3699 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Venetoclax and ibrutinib for patients with relapsed/refractory chronic lymphocytic leukemia
Niemann, Carsten, Levin, M., Dubois, J., Kersting, S., Enggaard, L., Veldhuis, G. J., Mous, R., Mellink, C. H. M., Dobber, J. A., Poulsen, C. B., Frederiksen, H., Janssens, A., Schjødt, I., Dompeling, E. C., Ranti, J., Mattsson, M., Bellido, M., Tran, H. T. T., Nasserinejad, K. & Kater, A. P., 2021, In: Blood. 137, 8, p. 1117-1120Research output: Contribution to journal › Letter › Research › peer-review
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COVID-19 Infection in Patients with Chronic Lymphocytic Leukemia Receiving Acalabrutinib in the Phase 3B ASSURE Study
Niemann, Carsten, Awan, F. T., Fogliatto, L., Nikitin, E., Samoilova, O., Habib, A., Foroutanpour, K., Kuptsova-Clarkson, N. & Opat, S., 2022, In: HemaSphere. 6, 10, p. E780Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with CLL have a lower risk of death from COVID-19 in the Omicron era
Niemann, Carsten, da Cunha-Bang, C., Helleberg, M., Ostrowski, Sisse Rye & Brieghel, C., 2022, In: Blood. 140, 5, p. 445-450 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cost-effectiveness targeting CLL
Niemann, Carsten, 2020, In: Blood. 136, 17, p. 1896-1898Research output: Contribution to journal › Editorial › Research › peer-review
- Published
BTK inhibitors: safety + efficacy = outcome
Niemann, Carsten, 2023, In: Blood. 142, 8, p. 679-680 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Immediate COVID-19 treatment in CLL
Niemann, Carsten, 2023, In: Blood. 141, 18, p. 2167-2168 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Prediction of clinical outcome in CLL based on recurrent gene mutations, CLL-IPI variables, and (para)clinical data
Parviz, M., Brieghel, C., Agius, R. & Niemann, Carsten, 2022, In: Blood advances. 6, 12, p. 3716-3728 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identifying CLL patients at high risk of atrial fibrillation on treatment using machine learning
Parviz, M., Agius, R., Rotbain, E. C., Vainer, N., Aarup, K. & Niemann, Carsten, 2024, In: Leukemia and Lymphoma. 65, 4, p. 449-459 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Durable benefit of rituximab maintenance post-autograft in patients with relapsed follicular lymphoma: 12-year follow-up of the EBMT lymphoma working party Lym1 trial
Pettengell, R., Uddin, R., Boumendil, A., Johnson, R., Metzner, B., Martín, A., Romejko-Jarosinska, J., Bence-Bruckler, I., Giri, P., Niemann, Carsten, Robinson, S. P., Kimby, E., Schmitz, N., Dreger, P., Goldstone, A. H. & Montoto, S., 2021, In: Bone Marrow Transplantation. 56, 6, p. 1413-1421 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reproducible diagnosis of chronic lymphocytic leukemia by flow cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation project
Rawstron, A. C., Kreuzer, K., Soosapilla, A., Spacek, M., Stehlikova, O., Gambell, P., Mciver-brown, N., Villamor, N., Psarra, K., Arroz, M., Milani, R., De La Serna, J., Cedena, M. T., Jaksic, O., Nomdedeu, J., Moreno, C., Rigolin, G. M., Cuneo, A., Johansen, P., Johnsen, H. E. & 13 others, , 2018, In: Cytometry. Part B: Clinical Cytometry. 94, 1, p. 121-128 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased incidence rates of positive blood cultures shortly after chemotherapy compared to radiotherapy among individuals treated for solid malignant tumours
Roen, A., Terrones, C., Bannister, W., Helleberg, M., Andersen, M. A., Niemann, Carsten, Daugaard, G., Specht, Lena, Mocroft, A., Reekie, J. & Lundgren, Jens, 2023, In: Infection. 51, 11 p., 147–157.Research output: Contribution to journal › Journal article › Research › peer-review
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CLL-IPI applied in Binet A CLL: a nationwide cohort study
Rotbain, E. C., da Cunha-Bang, C., Brieghel, C. & Niemann, Carsten, 2022, In: Blood advances. 6, 21, p. 5698-5701 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Healthcare Utilization and Comorbidity in Chronic Lymphocytic Leukemia
Rotbain, E. C., Rostgaard, K., Andersen, M. A., Da Cunha-Bang, C., Niemann, Carsten, Frederiksen, H. & Hjalgrim, Henrik, 2021, In: Clinical Epidemiology. 13, p. 1155-1165 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The CLL comorbidity index in a population-based cohort: a tool for clinical care and research
Rotbain, E. C., Gordon, M. J., Vainer, N., Frederiksen, H., Hjalgrim, Henrik, Danilov, A. V. & Niemann, Carsten, 2022, In: Blood advances. 6, 8, p. 2701-2706 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IGHV mutational status and outcome for patients with chronic lymphocytic leukemia upon treatment: A danish nationwide population-based study
Rotbain, E. C., Frederiksen, H., Hjalgrim, Henrik, Rostgaard, K., Egholm, G. J., Zahedi, B., Poulsen, C. B., Enggard, L., Da Cunha-Bang, C. & Niemann, Carsten, 2020, In: Haematologica. 105, 6, p. 1621-1629 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping comorbidity in chronic lymphocytic leukemia: impact of individual comorbidities on treatment, mortality, and causes of death
Rotbain, E. C., Niemann, Carsten, Rostgaard, K., da Cunha-Bang, C., Hjalgrim, Henrik & Frederiksen, H., 2021, In: Leukemia. 35, p. 2570–2580Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of type 2 diabetes on mortality, cause of death, and treatment in chronic lymphocytic leukemia
Rotbain, E. C., Allmer, C., Rostgaard, K., Andersen, M. A., Vainer, N., da Cunha-Bang, C., Parikh, S. A., Rabe, K. G., Hjalgrim, Henrik, Frederiksen, H., Slager, S. L. & Niemann, Carsten, 2023, In: American Journal of Hematology. 98, 8, p. 1236-1245 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
Scarfò, L., Chatzikonstantinou, T., Rigolin, G. M., Quaresmini, G., Motta, M., Vitale, C., Garcia-Marco, J. A., Hernández-Rivas, J. Á., Mirás, F., Baile, M., Marquet, J., Niemann, C. U., Reda, G., Munir, T., Gimeno, E., Marchetti, M., Quaglia, F. M., Varettoni, M., Delgado, J., Iyengar, S. & 62 others, , 2020, In: Leukemia. 34, 9, p. 2354-2363 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in primary and secondary hemostasis in patients with CLL treated with venetoclax and ibrutinib
Svanberg, R., Ostrowski, Sisse Rye, Nasserinejad, K., Kersting, S., Dobber, J. A., Mattson, M., Tran, H. T. T., Levin, M., Mous, R., Kater, A. P. & Niemann, Carsten, 2020, In: Leukemia and Lymphoma. 61, 14, p. 3422-3431 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
Svanberg, R., MacPherson, C., Zucco, A., Agius, R., Faitova, T., Andersen, M. A., da Cunha-Bang, C., Gjærde, L. K., Møller, M. E. E., Brooks, P. T., Lindegaard, B., Sejdic, A., Harboe, Z. B., Gang, A. O., Hersby, D. S., Brieghel, C., Nielsen, S. D., Podlekareva, D., Hald, A., Bay, J. T. & 6 others, , 2022, In: Communications Medicine. 2, 15 p., 114.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting the tumor microenvironment in chronic lymphocytic leukemia
Svanberg, R., Janum, S., Patten, P. E. M., Ramsay, A. G. & Niemann, Carsten, 2021, In: Haematologica. 106, 9, p. 2312-2324Research output: Contribution to journal › Review › Research › peer-review
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Improved Innate Immune Function in Patients with Chronic Lymphocytic Leukemia Treated with Targeted Therapy in Clinical Trials
Svanberg Teglgaard, R., Marquart, Hanne Vibeke Hansen, Hartling, Hans Jakob Stilling, Bay, Jakob Thaning, da Cunha-Bang, C., Brieghel, C., Faitová, T., Enggaard, L., Kater, A. P., Levin, M. D., Kersting, S., Ostrowski, Sisse Rye & Niemann, Carsten, 2024, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 30, 9, p. 1959-1971 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk of haematologic cancers among individuals tested for Borrelia burgdorferi antibodies, and Borrelia burgdorferi seropositive individuals: a nationwide population-based matched cohort study
Tetens, M. M., Omland, L. H., Dessau, R., Ellermann-Eriksen, S., Andersen, N. S., Jørgensen, C. S., Østergaard, C., Bodilsen, J., Søgaard, K. K., Bangsborg, Jette Marie, Nielsen, Alex Christian Yde, Møller, J. K., Chen, M., Niemann, Carsten, Lebech, Anne-Mette & Obel, Niels, 2024, In: Clinical Microbiology and Infection. 30, 2, p. 231-239 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-world outcomes upon second-line treatment in patients with chronic lymphocytic leukaemia
Vainer, N., Aarup, K., Andersen, M. A., Wind-Hansen, L., Nielsen, T., Frederiksen, H., Enggaard, L., Poulsen, Christian Bjørn, Niemann, Carsten & Rotbain, E. C., 2023, In: British Journal of Haematology. 201, 5, p. 874-886 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble CD52 is an indicator of disease activity in chronic lymphocytic leukemia
Vojdeman, F. J., Herman, S. E. M., Kirkby, N., Wiestner, A., van T' Veer, M. B., Tjønnfjord, G. E., Itälä-Remes, M. A., Kimby, E., Farooqui, M. Z., Polliack, A., Wu, K. L., Doorduijn, J. K., Alemayehu, W. G., Wittebol, S., Kozak, T., Walewski, J., Abrahamse-Testroote, M. C. J., van Oers, M. H. J., Geisler, C. H. & Niemann, Carsten, 2017, In: Leukemia and Lymphoma. 58, 10, p. 2356-2362Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic lymphocytic leukaemia clones are detectable decades before diagnosis
Vojdeman, F. J., Helby, J., Pedersen, L. B., Brieghel, C., Andersen, M. A., Nordestgaard, Børge, Bojesen, Stig Egil & Niemann, Carsten, 2022, In: British Journal of Haematology. 196, 3, p. 784-787Research output: Contribution to journal › Letter › Research › peer-review
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Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations
Wierda, W. G., Rawstron, A., Cymbalista, F., Badoux, X., Rossi, D., Brown, J. R., Egle, A., Abello, V., Cervera Ceballos, E., Herishanu, Y., Mulligan, S. P., Niemann, C. U., Diong, C. P., Soysal, T., Suzuki, R., Tran, H. T. T., Wu, S. J., Owen, C., Stilgenbauer, S., Ghia, P. & 1 others, , 2021, In: Leukemia. 35, 11, p. 3059-3072 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Personalized survival probabilities for SARS-CoV-2 positive patients by explainable machine learning
Zucco, Adrian G., Agius, R., Svanberg, R., Moestrup, K. S., Marandi, R. Z., MacPherson, C. R., Lundgren, Jens, Ostrowski, Sisse Rye & Niemann, Carsten, 2022, In: Scientific Reports. 12, 13879.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk of new malignancies among patients with CLL treated with chemotherapy: results of a Danish population-based study
da Cunha-Bang, C., Rostgaard, K., Andersen, M. A., Rotbain, E. C., Grønbæk, Kirsten, Frederiksen, H., Niemann, Carsten & Hjalgrim, Henrik, 2021, In: British Journal of Haematology. 193, 2, p. 339-345Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting Bruton's Tyrosine Kinase Across B-Cell Malignancies
da Cunha-Bang, C. & Niemann, Carsten, 2018, In: Drugs. 78, 16, p. 1653-1663Research output: Contribution to journal › Journal article › Research › peer-review
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Serological response following vaccination with BNT162b2 mRNA in patients with chronic lymphocytic leukemia
da Cunha-Bang, C., Kirkby, N. S., Friis-Hansen, Lennart Jan & Niemann, Carsten, 2022, In: Leukemia and Lymphoma. 63, 2, p. 503-505Research output: Contribution to journal › Letter › Research › peer-review
ID: 185059285
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Cocreated Smartphone App to Improve the Quality of Life of Adolescents and Young Adults with Cancer (Kræftværket): Protocol for a Quantitative and Qualitative Evaluation
Research output: Contribution to journal › Journal article › Research › peer-review
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153
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Using Cocreation in the Process of Designing a Smartphone App for Adolescents and Young Adults With Cancer: Prototype Development Study
Research output: Contribution to journal › Journal article › Research › peer-review
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130
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Machine learning can identify newly diagnosed patients with CLL at high risk of infection
Research output: Contribution to journal › Journal article › Research › peer-review
Published