Carlos Henriquez Olguín
Postdoc, Assistant Professor
The rapid rise in the prevalence of obesity, diabetes, and physical inactivity has significantly contributed to the increasing global burden of noncommunicable diseases. Skeletal muscle, the largest tissue in the body, possesses remarkable plasticity and represents a key pharmacological target to combat these diseases. Skeletal muscle redox signaling has emerged as a novel regulator of skeletal muscle metabolism but the molecular mechanisms involved are still not well understood. Our research focuses on connecting intracellular redox signaling and skeletal muscle metabolism in the context of metabolic diseases.
Recent Selected Publications
Henriquez-Olguin, C., Knudsen, J.R., Raun, S.H. et al. Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. Nature Commun 10, 4623 (2019).
Henriquez-Olguin C., Boronat, S. et al. NADPH oxidases in skeletal muscle: Emerging roles in redox signaling and metabolism. Antioxid Redox Signal. 31(18):1371-1410 (2019)
Henriquez-Olguin C, Baghersad L, Arab-Ceschia L, Raun SH., et al. Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2. Redox Biology 24, 101188 (2019)
Raun, S.H., Henriquez-Olguin, C., Karavaeva, I. et al. Housing temperature influences exercise training adaptations in mice. Nature Commun 11, 1560 (2020).
Primary fields of research
- Skeletal Muscle Metabolism
- Redox Signaling
- Insulin Action
- Exercise Physiology
ResearcherID: K-7671-2012
Scopus Author ID: 35102305800
ID: 166646715
Most downloads
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222
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The gut microbiome on a periodized low-protein diet is associated with improved metabolic health
Research output: Contribution to journal › Journal article › peer-review
Published -
147
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Low- and high-protein diets do not alter ex vivo insulin action in skeletal muscle
Research output: Contribution to journal › Journal article › peer-review
Published -
143
downloads
Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2
Research output: Contribution to journal › Journal article › peer-review
Published