Barbara Ann Halkier

Barbara Ann Halkier

Professor


  1. 2024
  2. Published

    An UMAMIT-GTR transporter cascade controls glucosinolate seed loading in Arabidopsis

    Sanden, Niels Christian Holm, Kanstrup, Christa, Crocoll, C., Schulz, Alexander, Nour-Eldin, Hussam Hassan, Halkier, Barbara Ann & Xu, Deyang, 2024, In: Nature Plants. 10, p. 172-179

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Export of defensive glucosinolates is key for their accumulation in seeds

    Xu, Deyang, Sanden, Niels Christian Holm, Hansen, Line Lykke, Belew, Zeinu Mussa, Madsen, S. R., Meyer, L., Jørgensen, M. E., Hunziker, P., Veres, D., Crocoll, C., Schulz, Alexander, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2023, In: Nature. 617, p. 132-138

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    GET-Mediated Export of Defensive Glucosinolates is Key for Seed Accumulation

    Xu, Deyang, Sanden, Niels Christian Holm, Hansen, Line Lykke, Belew, Zeinu Mussa, Madsen, S. R., Meyer, L., Jørgensen, M. E., Hunziker, P., Veres, D., Crocoll, C., Schulz, Alexander, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2023.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  6. Published

    Identification of key amino acid residues in AtUMAMIT29 for transport of glucosinolates

    Meyer, L., Crocoll, C., Halkier, Barbara Ann, Mirza, Osman Asghar & Xu, Deyang, 2023, In: Frontiers in Plant Science. 14, 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories

    Poborsky, Michal, Crocoll, C., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2023, In: Microbial Cell Factories. 22, 10 p., 219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2022
  9. Published

    Harnessing beneficial microbes from Danish natural soils to biostimulate plant nutrition

    Xu, Deyang, Dethier, L. & Halkier, Barbara Ann, 13 Nov 2022.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  10. Published

    Comparison of Genome and Plasmid-Based Engineering of Multigene Benzylglucosinolate Pathway in Saccharomyces cerevisiae

    Wang, Cuiwei, Poborsky, Michal, Crocoll, C., Nødvig, C. S., Mortensen, U. H. & Halkier, Barbara Ann, 2022, In: Applied and Environmental Microbiology. 88, 22, 15 p., e00978-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Prospects to improve the nutritional quality of crops. Food and Energy Security

    Scharff, L., Saltenis, V. L. R., Jensen, P. E., Baekelandt, A., Burgess, A. J., Burow, M., Ceriotti, A., Cohan, J-P., Geu-Flores, F., Halkier, B. A., Haslam, R. P., Inzé, D., Lankhorst, R. K., Murchie, E., Napier, J. A., Nacry, P., Parry, M. A. J., Santino, A., Scarano, A., Sparvoli, F. & 2 others, Wilhelm, R. & Pribil, Mathias, 2022, In: Food and Energy Security. 11, 1, 14 p., e327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The ins and outs of transporters at plasma membrane and tonoplast in plant specialized metabolism: [Correction]

    Xu, Deyang & Halkier, Barbara Ann, 2022, In: Natural Product Reports. 39, 7, p. 1483-1491

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Transport engineering in microbial cell factories producing plant-specialized metabolites

    Belew, Zeinu Mussa, Poborsky, Michal, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2022, In: Current Opinion in Green and Sustainable Chemistry. 33, 100576.

    Research output: Contribution to journalReviewResearchpeer-review

  14. 2021
  15. Published

    Bioengineering potato plants to produce benzylglucosinolate for improved broad-spectrum pest and disease resistance

    González-Romero, M. E., Rivera, C., Cancino, K., Geu-Flores, Fernando, Cosio, E. G., Ghislain, M. & Halkier, Barbara Ann, 2021, In: Transgenic Research. 30, p. 649-660 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Engineering and optimization of the 2-phenylethylglucosinolate production in Nicotiana benthamiana by combining biosynthetic genes from Barbarea vulgaris and Arabidopsis thaliana

    Wang, Cuiwei, Crocoll, C., Agerbirk, Niels & Halkier, Barbara Ann, 2021, In: Plant Journal. 106, 4, p. 978-992

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Herbivore feeding preference corroborates optimal defense theory for specialized metabolites within plants

    Hunziker, P., Lambertz, S. K., Weber, K., Crocoll, C., Halkier, Barbara Ann & Schulz, Alexander, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 47, e2111977118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2020
  19. Published

    Characterization of Arabidopsis CYP79C1 and CYP79C2 by Glucosinolate Pathway Engineering in Nicotiana benthamiana Shows Substrate Specificity Toward a Range of Aliphatic and Aromatic Amino Acids

    Wang, Cuiwei, Dissing, M. M., Agerbirk, Niels, Crocoll, C. & Halkier, Barbara Ann, 2020, In: Frontiers in Plant Science. 11, 13 p., 57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    De novo indol-3-ylmethyl glucosinolate biosynthesis, and not long-distance transport, contributes to defence of Arabidopsis against powdery mildew

    Hunziker, P., Ghareeb, H., Wagenknecht, L., Crocoll, C., Halkier, Barbara Ann, Lipka, V. & Schulz, Alexander, 2020, In: Plant, Cell and Environment. 43, 6, p. 1571-1583 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    In Arabidopsis thaliana Substrate Recognition and Tissue- as Well as Plastid Type-Specific Expression Define the Roles of Distinct Small Subunits of Isopropylmalate Isomerase

    Lächler, K., Clauss, K., Imhof, J., Crocoll, C., Schulz, Alexander, Halkier, Barbara Ann & Binder, S., 2020, In: Frontiers in Plant Science. 11, 18 p., 808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2019
  23. Published

    Arabidopsis glucosinolate storage cells transform into phloem fibres at late stages of development

    Hunziker, P., Halkier, Barbara Ann & Schulz, Alexander, Aug 2019, In: Journal of Experimental Botany. 70, 16, p. 4305–4317

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    De novo production of benzyl glucosinolate in Escherichia coli

    Petersen, A., Crocoll, C. & Halkier, Barbara Ann, 1 Jul 2019, In: Metabolic Engineering. 54, p. 24-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Changing substrate specificity and iteration of amino acid chain elongation in glucosinolate biosynthesis through targeted mutagenesis of Arabidopsis methylthioalkylmalate synthase1

    Petersen, A., Gram Hansen, L., Mirza, N., Crocoll, C., Mirza, Osman Asghar & Halkier, Barbara Ann, Jul 2019, In: Bioscience Reports. 39, p. 1-15 BSR20190446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Identification of genes involved in shea butter biosynthesis from Vitellaria paradoxa fruits through transcriptomics and functional heterologous expression

    Wei, Y., Ji, B., Siewers, V., Xu, Deyang, Halkier, Barbara Ann & Nielsen, J., May 2019, In: Applied Microbiology and Biotechnology. 103, 9, p. 3727–3736

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    GTR-Mediated Radial Import Directs Accumulation of Defensive Glucosinolates to Sulfur-Rich Cells in the Phloem Cap of Arabidopsis Inflorescence Stem

    Xu, Deyang, Hunziker, P., Koroleva, O., Blennow, Andreas, Crocoll, C., Schulz, Alexander, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2019, In: Molecular Plant. 12, 11, p. 1474-1484

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2018
  29. Published

    Biotechnological approaches in glucosinolate production

    Petersen, A., Wang, Cuiwei, Crocoll, C. & Halkier, Barbara Ann, 2018, In: Journal of Integrative Plant Biology. 60, 12, p. 1231-1248

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Differential roles of glucosinolates and camalexin at different stages of Agrobacterium-mediated transformation

    Shih, P., Chou, S., Mueller, C., Halkier, Barbara Ann, Deeken, R. & Lai, E., 2018, In: Molecular Plant Pathology. 19, 8, p. 1956-1970 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Dynamic Modeling of Indole Glucosinolate Hydrolysis and Its Impact on Auxin Signaling

    Vik, D., Mitarai, Namiko, Wulff, N., Halkier, Barbara Ann & Burow, Meike, 2018, In: Frontiers in Plant Science. 9, 16 p., 550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    How to prove the existence of metabolons?

    Bassard, J. A. & Halkier, Barbara Ann, 2018, In: Phytochemistry Reviews. 17, 2, p. 211-227 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Localization of the glucosinolate biosynthetic enzymes reveals distinct spatial patterns for the biosynthesis of indole and aliphatic glucosinolates

    Kjeldgaard-Nintemann, Sebastian J, Hunziker, P., Andersen, T. G., Schulz, Alexander, Burow, Meike & Halkier, Barbara Ann, 2018, In: Physiologia Plantarum. 163, 2, p. 138-154 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2017
  35. Published

    Albugo-imposed changes to tryptophan-derived antimicrobial metabolite biosynthesis may contribute to suppression of non-host resistance to Phytophthora infestans in Arabidopsis thaliana

    Prince, D. C., Rallapalli, G., Xu, Deyang, Schoonbeek, H., Cevik, V., Asai, S., Kemen, E., Cruz-Mireles, N., Kemen, A., Belhaj, K., Schornack, S., Kamoun, S., B Holub, E., Halkier, Barbara Ann & Jones, J. D. G., 2017, In: B M C Biology. 15, 22 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Advances in methods for identification and characterization of plant transporter function

    Larsen, B., Xu, Deyang, Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2017, In: Journal of Experimental Botany. 68, 15, p. 4045-4056 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole

    Payne, R., Xu, Deyang, Foureau, E., Ines Soares Teto Carqueijeiro, M., Oudin, A., Dugé de Bernonville, T., Novák, V., Burow, Meike, Olsen, C. E., Jones, D. M., C. Tatsis, E., Pendleton, A., Halkier, Barbara Ann, Geu-Flores, Fernando, Courdavault, V., Nour-Eldin, Hussam Hassan & O'Connor, S. E., 2017, In: Nature Plants. 3, 9 p., 16208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    CASCADE, a platform for controlled gene amplification for high, tunable and selection-free gene expression in yeast

    Strucko, T., Buron, L. D., Jarczynska, Z. D., Nødvig, C. S., Mølgaard, L., Halkier, Barbara Ann & Mortensen, U. H., 2017, In: Scientific Reports. 7, 12 p., 41431.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    How does a plant orchestrate defense in time and space? Using glucosinolates in Arabidopsis as case study

    Burow, Meike & Halkier, Barbara Ann, 2017, In: Current Opinion in Plant Biology. 38, p. 142-147 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Identification of iridoid glucoside transporters in Catharanthus roseus

    Larsen, B., Fuller, V. L., Pollier, J., Van Moerkercke, A., Schweizer, F., Payne, R., Colinas, M., O'Connor, S. E., Goossens, A. & Halkier, Barbara Ann, 2017, In: Plant and Cell Physiology. 58, 9, p. 1507-1518 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]

    Jørgensen, M. E., Xu, Deyang, Crocoll, C., Ernst, H. A., Ramírez, D., Motawie, Mohammed Saddik, Olsen, C. E., Mirza, Osman Asghar, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2017, In: eLife. 6, 30 p., e19466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Reduction of antinutritional glucosinolates in Brassica oilseeds by mutation of genes encoding transporters

    Nour-Eldin, Hussam Hassan, Madsen, S. R., Engelen, S., Jørgensen, M. E., Olsen, C. E., Andersen, J. S., Seynnaeve, D., Verhoye, T., Fulawka, R., Denolf, P. & Halkier, Barbara Ann, 2017, In: Nature Biotechnology. 35, 4, p. 377-382 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Rhizosecretion of stele-synthesized glucosinolates and their catabolites requires GTR-mediated import in Arabidopsis

    Xu, Deyang, Hanschen, F. S., Witzel, K., Kjeldgaard-Nintemann, Sebastian J, Nour-Eldin, Hussam Hassan, Schreiner, M. & Halkier, Barbara Ann, 2017, In: Journal of Experimental Botany. 68, 12, p. 3205-3214 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Unravelling protein-protein interaction networks linked to aliphatic and indole glucosinolate biosynthetic pathways in arabidopsis

    Kjeldgaard-Nintemann, Sebastian J, Vik, D., Svozil, J., Bak, M., Baerenfaller, K., Burow, Meike & Halkier, Barbara Ann, 2017, In: Frontiers in Plant Science. 8, 20 p., 2028.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Uptake Assays in Xenopus laevis Oocytes Using Liquid Chromatography-mass Spectrometry to Detect Transport Activity

    Jørgensen, M., Crocoll, C., Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2017, In: Bio-protocol. 7, 20, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2016
  47. Published

    CB5C affects the glucosinolate profile in Arabidopsis thaliana

    Vik, D., Crocoll, C., Andersen, T. G., Burow, Meike & Halkier, Barbara Ann, 2016, In: Plant Signalling & Behavior. 11, 8, 6 p., e1160189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    A western blot protocol for detection of proteins heterologously expressed in Xenopus laevis oocytes

    Jørgensen, M. E., Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2016, Biotechnology of plant secondary metabolism: methods and protocols. Fett-Neto, A. G. (ed.). Springer, p. 99-107 9 p. (Methods in Molecular Biology, Vol. 1405).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  49. Published

    Analysis and quantification of glucosinolates

    Crocoll, C., Halkier, Barbara Ann & Burow, Meike, 2016, In: Current Protocols in Plant Biology. 1, p. 385-409 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Characterization of methylsulfinylalkyl glucosinolate specific polyclonal antibodies

    Mirza, N. M. A., Schulz, Alexander & Halkier, Barbara Ann, 2016, In: Journal of Plant Biochemistry and Biotechnology. 25, 4, p. 433-436 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Collection of apoplastic fluids from Arabidopsis thaliana leaves

    Madsen, S. R., Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2016, Biotechnology of plant secondary metabolism: methods and protocols. Springer, p. 35-42 8 p. (Methods in Molecular Biology, Vol. 1405).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  52. Published

    Engineering of methionine chain elongation part of glucoraphanin pathway in E. coli

    Mirza, N. M. A., Crocoll, C., Olsen, C. E. & Halkier, Barbara Ann, 2016, In: Metabolic Engineering. 35, p. 31-37 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Functional expression and characterization of plant ABC transporters in Xenopus laevis oocytes for transport engineering purposes

    Xu, Deyang, Veres, D., Belew, Zeinu Mussa, Olsen, C. E., Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2016, Synthetic biology and metabolic engineering in plants and microbes : Part B: Plant metabolism. p. 207-224 8 p. (Methods in Enzymology, Vol. 576).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  54. Published

    General introduction to glucosinolates

    Halkier, Barbara Ann, 2016, Advances in botanical research. Elsevier, Vol. 80. p. 1-14 14 p. (Advances in Botanical Research).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  55. Published

    Improving analytical methods for protein-protein interaction through implementation of chemically inducible dimerization

    Andersen, T. G., Kjeldgaard-Nintemann, Sebastian J, Marek, M., Halkier, Barbara Ann, Schulz, Alexander & Burow, Meike, 2016, In: Scientific Reports. 6, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Optimization of engineered production of the glucoraphanin precursor dihomomethionine in Nicotiana benthamiana

    Crocoll, C., Mirza, N. M. A., Reichelt, M., Gershenzon, J. & Halkier, Barbara Ann, 2016, In: Frontiers in Bioengineering and Biotechnology. 4, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Phosphorylation at serine 52 and 635 does not alter the transport properties of glucosinolate transporter AtGTR1

    Jørgensen, M. E., Olsen, C. E., Halkier, Barbara Ann & Nour-Eldin, Hussam Hassan, 2016, In: Plant Signalling & Behavior. 11, 2, 6 p., e1071751.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Sinapic acid as inhibitor of the SOS response in Eschericha coli induced by ciprofloxacin

    Nascimento da Silva, L. C., Madsen, S. R., Crocoll, C., Halkier, Barbara Ann & Løbner-Olesen, A., 2016, In: Planta Medica. 82, S 01, 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  59. Published

    The Arabidopsis NPF3 protein is a GA transporter

    Tal, I., Zhang, Y., Jørgensen, M. E., Pisanty, O., Barbosa, I. C. R., Zourelidou, M., Regnault, T., Crocoll, C., Olsen, C. E., Weinstain, R., Schwechheimer, C., Halkier, Barbara Ann, Nour-Eldin, Hussam Hassan, Estelle, M. & Shani, E., 2016, In: Nature Communications. 7, 20 p., 11486.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 4237963