Anne-Vibeke Lænkholm
Clinical Associate Professor
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A Multi-Stain Breast Cancer Histological Whole-Slide-Image Data Set from Routine Diagnostics
Weitz, P., Valkonen, M., Solorzano, L., Carr, C., Kartasalo, K., Boissin, C., Koivukoski, S., Kuusela, A., Rasic, D., Feng, Y., Pouplier, S. S., Sharma, A., Ledesma Eriksson, K., Latonen, L., Lænkholm, Anne-Vibeke, Hartman, J., Ruusuvuori, P. & Rantalainen, M., 2023, In: Scientific Data. 10, 6 p., 562.Research output: Contribution to journal › Journal article › Research › peer-review
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A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells
Thrane, Susan, Pedersen, A. M., Thomsen, M. B. H., Kirkegaard, T., Rasmussen, B. B., Duun-Henriksen, A. K., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E. & Yde, C. W., 6 Aug 2015, In: Oncogene. 34, 32, p. 4199-210 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy
Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjuvant chemotherapy in patients with ER-negative/HER2-negative, T1abN0 breast cancer: a nationwide study
Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2023, In: Breast Cancer Research and Treatment. 198, 1, p. 103-112 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjuvant treatment with trastuzumab of patients with HER2-positive, T1a-bN0M0 breast tumors: A systematic review and meta-analysis
Hassing, C. M. S., Nielsen, Dorte Lisbet, Knoop, A. S., Tvedskov, Tove Filtenborg, Kroman, Niels Thorndahl, Lænkholm, Anne-Vibeke, Juhl, C. B. & Kümler, Iben, 2023, In: Critical Reviews in Oncology/Hematology. 184, 11 p., 103952.Research output: Contribution to journal › Review › Research › peer-review
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Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer
Nielsen, K. V., Ejlertsen, Bent Laursen, Müller, S., Møller, S., Rasmussen, B. B., Balslev, E., Lænkholm, Anne-Vibeke, Christiansen, P. & Mouridsen, H. T., 2011, In: Breast Cancer Research and Treatment. 127, 2, p. 345-355Research output: Contribution to journal › Journal article › Research › peer-review
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An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)
Lænkholm, Anne-Vibeke, Grabau, D., Talman, M. M., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Rasmussen, B. B., 2018, In: Acta Oncologica. 57, 1, p. 83-89 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An international study to increase concordance in Ki67 scoring
Polley, M-Y. C., Leung, S. C. Y., Gao, D., Mastropasqua, M. G., Zabaglo, L. A., Bartlett, J. M. S., McShane, L. M., Enos, R. A., Badve, S. S., Bane, A. L., Borgquist, S., Fineberg, S., Lin, M-G., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Moriya, T., Ohi, Y., Osborne, C. K. & 11 others, , 2015, In: Modern Pathology. 28, 6, p. 778-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, , 2019, In: Histopathology. 75, 2, p. 225-235Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration
Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, , 2016, In: npj Breast Cancer. 2, p. 16014Research output: Contribution to journal › Journal article › Research › peer-review
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Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer
Holten-Rossing, H., Talman, M. M., Jylling, A. M. B., Lænkholm, Anne-Vibeke, Kristensson, M. & Vainer, B., Dec 2017, In: Histopathology. 71, 6, p. 866-873Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group
Nielsen, T. O., Leung, S. C. Y., Rimm, D. L., Dodson, A., Acs, B., Badve, S., Denkert, C., Ellis, M. J., Fineberg, S., Flowers, M., Kreipe, H. H., Laenkholm, A-V., Pan, H., Penault-Llorca, F. M., Polley, M-Y., Salgado, R., Smith, I. E., Sugie, T., Bartlett, J. M. S., McShane, L. M. & 2 others, , 2021, In: JNCI - Journal of the National Cancer Institute. 113, 7, p. 808–819Research output: Contribution to journal › Journal article › Research › peer-review
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Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer
Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.Research output: Contribution to journal › Journal article › Research › peer-review
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Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial
Asleh, K., Lyck Carstensen, S., Tykjaer Jørgensen, C. L., Burugu, S., Gao, D., Won, J. R., Jensen, M., Balslev, E., Lænkholm, Anne-Vibeke, Nielsen, Dorte Lisbet, Ejlertsen, Bent Laursen & Nielsen, T. O., 15 May 2019, In: International Journal of Cancer. 144, 10, p. 2578-2586 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benefit of adjuvant chemotherapy and trastuzumab in patients with HER2-positive, node-negative breast tumors ≤ 10 mm: a nationwide study
Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2022, In: Breast Cancer Research and Treatment. 196, 1, p. 197-206Research output: Contribution to journal › Journal article › Research › peer-review
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Breast cancer in situ. From pre-malignant lesion of uncertain significance to well-defined non-invasive malignant lesion. The Danish Breast Cancer Cooperative Group Register 1977-2007 revisited
Lænkholm, Anne-Vibeke, Jensen, M., Kroman, Niels Thorndahl & Rank, F., 2008, In: Acta Oncologica. 47, 4, p. 765-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Breast cancer stem cells: A moving target for cancer nanomedicine
Mollenhauer, J., Knoop, A., Bak, M., Lænkholm, Anne-Vibeke, Thomassen, M., Kruse, T. A. & Hoilund-Carlsen, P. F., Dec 2012, In: European Journal of Nanomedicine. 4, 2-4, p. 59-72 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
Olafsdottir, E. J., Borg, A., Jensen, M., Gerdes, Anne-Marie Axø, Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, Bent Laursen, Sønderstrup, I. M. H., Hovig, E., Lænkholm, Anne-Vibeke, Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In: British Journal of Cancer. 123, 11, p. 1608-1615 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calcium electroporation as an adjunct therapy for pembrolizumab-resistant bladder cancer: a case report
Vissing, M., Munch Larsen, L., Christensen, A. J., Öwall, L., Sinius Pouplier, S., Lænkholm, Anne-Vibeke & Gehl, Julie, 2023, In: Acta Oncologica. 62, 6, p. 614-620 7 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Capsulectomy Can Successfully Treat Chronic Encapsulated Breast Seroma: A Case Report
Fosheim, K., Bojesen, S., Troestrup, H. & Lænkholm, Anne-Vibeke, 2022, In: Cureus. 14, 1, 5 p., e21677.Research output: Contribution to journal › Journal article › Research › peer-review
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Carcinoma in situ mammae
Lænkholm, Anne-Vibeke, Hoffmann, J. & Rank, F. E., 10 Sep 2007, In: Ugeskrift for Laeger. 169, 37, p. 3087-90 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Classical pathological variables recorded in the Danish Breast Cancer Cooperative Group's register 1978-2006
Kiaer, H. W., Lænkholm, Anne-Vibeke, Nielsen, B. B. & Bjerre, K. D., 2008, In: Acta Oncologica. 47, 4, p. 778-83 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling
Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, Thomas van Overeem, Ejlertsen, Bent Laursen, Gerdes, Anne-Marie Axø & Thomassen, M., 2013, In: P L o S One. 8, 5, 12 p., e64268.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG
Soenderstrup, I. M. H., Lænkholm, Anne-Vibeke, Jensen, M. B., Eriksen, J. O., Gerdes, Anne-Marie Axø, Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 95-101Research output: Contribution to journal › Journal article › Research › peer-review
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Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis
Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Kruse, T. A. & Thomassen, M., 2015, In: OncoTarget. 6, 8, p. 5634-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
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The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
Research output: Contribution to journal › Journal article › Research › peer-review
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