Anne-Vibeke Lænkholm

Anne-Vibeke Lænkholm

Clinical Associate Professor


  1. Published

    A Multi-Stain Breast Cancer Histological Whole-Slide-Image Data Set from Routine Diagnostics

    Weitz, P., Valkonen, M., Solorzano, L., Carr, C., Kartasalo, K., Boissin, C., Koivukoski, S., Kuusela, A., Rasic, D., Feng, Y., Pouplier, S. S., Sharma, A., Ledesma Eriksson, K., Latonen, L., Lænkholm, Anne-Vibeke, Hartman, J., Ruusuvuori, P. & Rantalainen, M., 2023, In: Scientific Data. 10, 6 p., 562.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells

    Thrane, Susan, Pedersen, A. M., Thomsen, M. B. H., Kirkegaard, T., Rasmussen, B. B., Duun-Henriksen, A. K., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E. & Yde, C. W., 6 Aug 2015, In: Oncogene. 34, 32, p. 4199-210 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy

    Larsen, M. S., Bjerre, K., Lykkesfeldt, A. E., Giobbie-Hurder, A., Lænkholm, Anne-Vibeke, Henriksen, K. L., Ejlertsen, Bent Laursen & Rasmussen, B. B., Oct 2012, In: Breast (Edinburgh, Scotland). 21, 5, p. 662-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Adjuvant chemotherapy in patients with ER-negative/HER2-negative, T1abN0 breast cancer: a nationwide study

    Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2023, In: Breast Cancer Research and Treatment. 198, 1, p. 103-112 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Adjuvant treatment with trastuzumab of patients with HER2-positive, T1a-bN0M0 breast tumors: A systematic review and meta-analysis

    Hassing, C. M. S., Nielsen, Dorte Lisbet, Knoop, A. S., Tvedskov, Tove Filtenborg, Kroman, Niels Thorndahl, Lænkholm, Anne-Vibeke, Juhl, C. B. & Kümler, Iben, 2023, In: Critical Reviews in Oncology/Hematology. 184, 11 p., 103952.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer

    Nielsen, K. V., Ejlertsen, Bent Laursen, Müller, S., Møller, S., Rasmussen, B. B., Balslev, E., Lænkholm, Anne-Vibeke, Christiansen, P. & Mouridsen, H. T., 2011, In: Breast Cancer Research and Treatment. 127, 2, p. 345-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    An inter-observer Ki67 reproducibility study applying two different assessment methods: on behalf of the Danish Scientific Committee of Pathology, Danish breast cancer cooperative group (DBCG)

    Lænkholm, Anne-Vibeke, Grabau, D., Talman, M. M., Balslev, E., Bak Jylling, A. M., Tabor, T. P., Johansen, M., Brügmann, A., Lelkaitis, G., Di Caterino, T., Mygind, H., Poulsen, T., Mertz, H., Søndergaard, G. & Rasmussen, B. B., 2018, In: Acta Oncologica. 57, 1, p. 83-89 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    An international study to increase concordance in Ki67 scoring

    Polley, M-Y. C., Leung, S. C. Y., Gao, D., Mastropasqua, M. G., Zabaglo, L. A., Bartlett, J. M. S., McShane, L. M., Enos, R. A., Badve, S. S., Bane, A. L., Borgquist, S., Fineberg, S., Lin, M-G., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Moriya, T., Ohi, Y., Osborne, C. K. & 11 others, Penault-Llorca, F. M., Piper, T., Porter, P. L., Sakatani, T., Salgado, R., Starczynski, J., Lænkholm, Anne-Vibeke, Viale, G., Dowsett, M., Hayes, D. F. & Nielsen, T. O., 2015, In: Modern Pathology. 28, 6, p. 778-86 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collaboration

    Leung, S. C. Y., Nielsen, T. O., Zabaglo, L. A., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Ehinger, A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A. V., Mastropasqua, M. G. & 15 others, Moriya, T., Nofech-Mozes, S., Osborne, C. K., Penault-Llorca, F. M., Piper, T., Sakatani, T., Salgado, R., Starczynski, J., Sugie, T., van der Vegt, B., Viale, G., Hayes, D. F., McShane, L. M., Dowsett, M. & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG), O. B. O. T. I. K. I. B. C. W. G. O. T. B. I. G. A. N. A. B. C. G. (., 2019, In: Histopathology. 75, 2, p. 225-235

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration

    Leung, S. C. Y., Nielsen, T. O., Zabaglo, L., Arun, I., Badve, S. S., Bane, A. L., Bartlett, J. M. S., Borgquist, S., Chang, M. C., Dodson, A., Enos, R. A., Fineberg, S., Focke, C. M., Gao, D., Gown, A. M., Grabau, D., Gutierrez, C., Hugh, J. C., Kos, Z., Lænkholm, A-V. & 14 others, Lin, M., Mastropasqua, M. G., Moriya, T., Nofech-Mozes, S., Osborne, C. K., Penault-Llorca, F. M., Piper, T., Sakatani, T., Salgado, R., Starczynski, J., Viale, G., Hayes, D. F., McShane, L. M. & Dowsett, M., 2016, In: npj Breast Cancer. 2, p. 16014

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer

    Holten-Rossing, H., Talman, M. M., Jylling, A. M. B., Lænkholm, Anne-Vibeke, Kristensson, M. & Vainer, B., Dec 2017, In: Histopathology. 71, 6, p. 866-873

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Assessment of Ki67 in Breast Cancer: Updated Recommendations from the International Ki67 in Breast Cancer Working Group

    Nielsen, T. O., Leung, S. C. Y., Rimm, D. L., Dodson, A., Acs, B., Badve, S., Denkert, C., Ellis, M. J., Fineberg, S., Flowers, M., Kreipe, H. H., Laenkholm, A-V., Pan, H., Penault-Llorca, F. M., Polley, M-Y., Salgado, R., Smith, I. E., Sugie, T., Bartlett, J. M. S., McShane, L. M. & 2 others, Dowsett, M. & Hayes, D. F., 2021, In: JNCI - Journal of the National Cancer Institute. 113, 7, p. 808–819

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer

    Larsen, S. L., Yde, C. W., Lænkholm, Anne-Vibeke, Rasmussen, B. B., Duun-Henriksen, A. K., Bak, M., Lykkesfeldt, A. E. & Kirkegaard, T., 8 Apr 2015, In: B M C Cancer. 15, 15 p., 239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial

    Asleh, K., Lyck Carstensen, S., Tykjaer Jørgensen, C. L., Burugu, S., Gao, D., Won, J. R., Jensen, M., Balslev, E., Lænkholm, Anne-Vibeke, Nielsen, Dorte Lisbet, Ejlertsen, Bent Laursen & Nielsen, T. O., 15 May 2019, In: International Journal of Cancer. 144, 10, p. 2578-2586 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Benefit of adjuvant chemotherapy and trastuzumab in patients with HER2-positive, node-negative breast tumors ≤ 10 mm: a nationwide study

    Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2022, In: Breast Cancer Research and Treatment. 196, 1, p. 197-206

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Breast cancer in situ. From pre-malignant lesion of uncertain significance to well-defined non-invasive malignant lesion. The Danish Breast Cancer Cooperative Group Register 1977-2007 revisited

    Lænkholm, Anne-Vibeke, Jensen, M., Kroman, Niels Thorndahl & Rank, F., 2008, In: Acta Oncologica. 47, 4, p. 765-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Breast cancer stem cells: A moving target for cancer nanomedicine

    Mollenhauer, J., Knoop, A., Bak, M., Lænkholm, Anne-Vibeke, Thomassen, M., Kruse, T. A. & Hoilund-Carlsen, P. F., Dec 2012, In: European Journal of Nanomedicine. 4, 2-4, p. 59-72 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status

    Olafsdottir, E. J., Borg, A., Jensen, M., Gerdes, Anne-Marie Axø, Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, Bent Laursen, Sønderstrup, I. M. H., Hovig, E., Lænkholm, Anne-Vibeke, Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In: British Journal of Cancer. 123, 11, p. 1608-1615 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Calcium electroporation as an adjunct therapy for pembrolizumab-resistant bladder cancer: a case report

    Vissing, M., Munch Larsen, L., Christensen, A. J., Öwall, L., Sinius Pouplier, S., Lænkholm, Anne-Vibeke & Gehl, Julie, 2023, In: Acta Oncologica. 62, 6, p. 614-620 7 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  20. Published

    Capsulectomy Can Successfully Treat Chronic Encapsulated Breast Seroma: A Case Report

    Fosheim, K., Bojesen, S., Troestrup, H. & Lænkholm, Anne-Vibeke, 2022, In: Cureus. 14, 1, 5 p., e21677.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Carcinoma in situ mammae

    Lænkholm, Anne-Vibeke, Hoffmann, J. & Rank, F. E., 10 Sep 2007, In: Ugeskrift for Laeger. 169, 37, p. 3087-90 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Classical pathological variables recorded in the Danish Breast Cancer Cooperative Group's register 1978-2006

    Kiaer, H. W., Lænkholm, Anne-Vibeke, Nielsen, B. B. & Bjerre, K. D., 2008, In: Acta Oncologica. 47, 4, p. 778-83 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling

    Larsen, M. J., Kruse, T. A., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Lykkesfeldt, A. E., Sørensen, K. P., Hansen, Thomas van Overeem, Ejlertsen, Bent Laursen, Gerdes, Anne-Marie Axø & Thomassen, M., 2013, In: P L o S One. 8, 5, 12 p., e64268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG

    Soenderstrup, I. M. H., Lænkholm, Anne-Vibeke, Jensen, M. B., Eriksen, J. O., Gerdes, Anne-Marie Axø, Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 95-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis

    Krøigård, A. B., Larsen, M. J., Lænkholm, Anne-Vibeke, Knoop, A. S., Jensen, J. D., Bak, M., Mollenhauer, J., Kruse, T. A. & Thomassen, M., 2015, In: OncoTarget. 6, 8, p. 5634-49 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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