Anne-Vibeke Lænkholm
Clinical Associate Professor
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Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study
Acs, B. & on behalf of the International Ki67 in Breast Cancer Working Group of the Breast International Group and North American Breast Cancer Group (BIG-NABCG), O. B. O. T. I. K. I. B. C. W. G. O. T. B. I. G. A. N. A. B. C. G. (., 2022, In: Modern Pathology. 35, 10, p. 1362-1369 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness
Andersen, L. V. B., Larsen, M. J., Davies, H., Degasperi, A., Nielsen, H. R., Jensen, L. A., Kroeldrup, L., Gerdes, Anne-Marie Axø, Lænkholm, Anne-Vibeke, Kruse, T. A., Nik-Zainal, S. & Thomassen, M., 2023, In: Breast Cancer Research. 25, 1, 10 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
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Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial
Asleh, K., Lyck Carstensen, S., Tykjaer Jørgensen, C. L., Burugu, S., Gao, D., Won, J. R., Jensen, M., Balslev, E., Lænkholm, Anne-Vibeke, Nielsen, Dorte Lisbet, Ejlertsen, Bent Laursen & Nielsen, T. O., 15 May 2019, In: International Journal of Cancer. 144, 10, p. 2578-2586 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of the change in cutoff values for human epidermal growth factor receptor 2 status by immunohistochemistry and fluorescence in situ hybridization: a study comparing conventional brightfield microscopy, image analysis-assisted microscopy, and interobserver variation
Atkinson, R., Mollerup, J., Lænkholm, Anne-Vibeke, Verardo, M., Hawes, D., Commins, D., Engvad, B., Correa, A., Ehlers, C. C. & Nielsen, K. V., 2011, In: Archives of Pathology & Laboratory Medicine. 135, 8, p. 1010-1016 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mortality rates among early-stage hormone receptor-positive breast cancer patients: a population-based cohort study in Denmark
Danish Breast Cancer Cooperative Group, D. B. C. C. G., 21 Sep 2011, In: Journal of the National Cancer Institute. 103, 18, p. 1363-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ONEST (Observers Needed to Evaluate Subjective Tests) Analysis of Stromal Tumour-Infiltrating Lymphocytes (sTILs) in Breast Cancer and Its Limitations
Cserni, B., Kilmartin, D., O’Loughlin, M., Andreu, X., Bagó-Horváth, Z., Bianchi, S., Chmielik, E., Figueiredo, P., Floris, G., Foschini, M. P., Kovács, A., Heikkilä, P., Kulka, J., Laenkholm, A. V., Liepniece-Karele, I., Marchiò, C., Provenzano, E., Regitnig, P., Reiner, A., Ryška, A. & 17 others, , 2023, In: Cancers. 15, 4, 11 p., 1199.Research output: Contribution to journal › Journal article › Research › peer-review
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PROCURE European consensus on breast cancer multigene signatures in early breast cancer management
Curigliano, G., Cardoso, F., Gnant, M., Harbeck, N., King, J., Lænkholm, Anne-Vibeke, Penault-Llorca, F. & Prat, A., 2023, In: npj Breast Cancer. 9, 8 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
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PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer
Dupont Jensen, J., Lænkholm, Anne-Vibeke, Knoop, A., Ewertz, M., Bandaru, R., Liu, W., Hackl, W., Barrett, J. C. & Gardner, H., 15 Feb 2011, In: Clinical Cancer Research. 17, 4, p. 667-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group
El Bairi, K., Haynes, H. R., Blackley, E., Fineberg, S., Shear, J., Turner, S., de Freitas, J. R., Sur, D., Amendola, L. C., Gharib, M., Kallala, A., Arun, I., Azmoudeh-Ardalan, F., Fujimoto, L., Sua, L. F., Liu, S. W., Lien, H. C., Kirtani, P., Balancin, M., El Attar, H. & 31 others, , 2021, In: npj Breast Cancer. 7, 1, 17 p., 150.Research output: Contribution to journal › Review › Research › peer-review
Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy
Elias, D., Vever, H., Lænkholm, Anne-Vibeke, Gjerstorff, M. F., Yde, C. W., Lykkesfeldt, A. E. & Ditzel, H. J., 9 Apr 2015, In: Oncogene. 34, 15, p. 1919-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Finnålsaspirationscytologi ved mammografiscreening
Engvad, B., Lænkholm, Anne-Vibeke, Schwartz, W. & Bak, M., 17 Aug 2009, In: Ugeskrift for Laeger. 171, 34, p. 2379-82 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prognostic impact of tumor MET expression among patients with stage IV gastric cancer: a Danish cohort study
Erichsen, R., Kelsh, M. A., Oliner, K. S., Nielsen, K. B., Frøslev, T., Lænkholm, Anne-Vibeke, Vyberg, M., Acquavella, J. & Sørensen, H. T., Jul 2016, In: Annals of Epidemiology. 26, 7, p. 500-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of prediction of local recurrence (LR) by Prosigna® (PAM50) in a Danish breast cancer cooperative group (DBCG) cohort of hormone receptor positive (HR+), postmenopausal early breast cancer (EBC) patients allocated to 5yr of endocrine therapy (ET)
Eriksen, J. O., Jensen, M., Lænkholm, Anne-Vibeke, Kibøll, T., Rasmussen, B. B., Knoop, A. S., Ferree, S., Haffner, T., Buckingham, W., Schaper, C. & Ejlertsen, B., 2016, In: Cancer Research. 76, 4 Supplement, 1 p., P2-08-10.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Capsulectomy Can Successfully Treat Chronic Encapsulated Breast Seroma: A Case Report
Fosheim, K., Bojesen, S., Troestrup, H. & Lænkholm, Anne-Vibeke, 2022, In: Cureus. 14, 1, 5 p., e21677.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of genes with altered expression in medullary breast cancer vs. ductal breast cancer and normal breast epithelia
Gjerstorff, M. F., Benoit, V. M., Lænkholm, Anne-Vibeke, Nielsen, O., Johansen, L. E. & Ditzel, H. J., Jun 2006, In: International Journal of Oncology. 28, 6, p. 1327-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice
Gonzalez-Ericsson, P. I., Stovgaard, E. S., Sua, L. F., Reisenbichler, E., Kos, Z., Carter, J. M., Michiels, S., Le Quesne, J., Nielsen, T. O., Lænkholm, A. V., Fox, S. B., Adam, J., Bartlett, J. M. S., Rimm, D. L., Quinn, C., Peeters, D., Dieci, M. V., Vincent-Salomon, A., Cree, I., Hida, A. I. & 55 others, , 2020, In: Journal of Pathology. 250, 5, p. 667-684Research output: Contribution to journal › Review › Research › peer-review
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Influence of storage temperature and high-temperature antigen retrieval buffers on results of immunohistochemical staining in sections stored for long periods
Grabau, D. A., Nielsen, O., Hansen, S., Nielsen, M. M., Lænkholm, Anne-Vibeke, Knoop, A. & Pfeiffer, P., 1998, In: Applied Immunohistochemistry. 6, 4, p. 209-213 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type 1 in breast cancer patients
Hansen, S., Overgaard, J., Rose, C., Knoop, A., Lænkholm, Anne-Vibeke, Andersen, J., Sørensen, F. B. & Andreasen, P. A., 13 Jan 2003, In: British Journal of Cancer. 88, 1, p. 102-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjuvant chemotherapy in patients with ER-negative/HER2-negative, T1abN0 breast cancer: a nationwide study
Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2023, In: Breast Cancer Research and Treatment. 198, 1, p. 103-112 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adjuvant treatment with trastuzumab of patients with HER2-positive, T1a-bN0M0 breast tumors: A systematic review and meta-analysis
Hassing, C. M. S., Nielsen, Dorte Lisbet, Knoop, A. S., Tvedskov, Tove Filtenborg, Kroman, Niels Thorndahl, Lænkholm, Anne-Vibeke, Juhl, C. B. & Kümler, Iben, 2023, In: Critical Reviews in Oncology/Hematology. 184, 11 p., 103952.Research output: Contribution to journal › Review › Research › peer-review
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Benefit of adjuvant chemotherapy and trastuzumab in patients with HER2-positive, node-negative breast tumors ≤ 10 mm: a nationwide study
Hassing, C. M. S., Mejdahl, M. K., Lænkholm, Anne-Vibeke, Kroman, Niels Thorndahl, Knoop, A. S. & Tvedskov, Tove Filtenborg, 2022, In: Breast Cancer Research and Treatment. 196, 1, p. 197-206Research output: Contribution to journal › Journal article › Research › peer-review
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Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery: a nationwide population-based study
Heeg, E., Jensen, M. B., Hølmich, Lisbet Rosenkrantz, Bodilsen, A., Tollenaar, R. A. E. M., Lænkholm, Anne-Vibeke, Offersen, B. V., Ejlertsen, Bent Laursen, Mureau, M. A. M. & Christiansen, P. M., 2020, In: British Journal of Surgery. 107, 13, p. 1762-1772Research output: Contribution to journal › Journal article › Research › peer-review
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Application of automated image analysis reduces the workload of manual screening of sentinel lymph node biopsies in breast cancer
Holten-Rossing, H., Talman, M. M., Jylling, A. M. B., Lænkholm, Anne-Vibeke, Kristensson, M. & Vainer, B., Dec 2017, In: Histopathology. 71, 6, p. 866-873Research output: Contribution to journal › Journal article › Research › peer-review
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Phage display derived human monoclonal antibodies isolated by binding to the surface of live primary breast cancer cells recognize GRP78
Jakobsen, C. G., Rasmussen, N., Lænkholm, Anne-Vibeke & Ditzel, H. J., 1 Oct 2007, In: Cancer Research. 67, 19, p. 9507-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PIK3CA mutations, PTEN, and pHER2 expression and impact on outcome in HER2-positive early-stage breast cancer patients treated with adjuvant chemotherapy and trastuzumab
Jensen, J. D., Knoop, A., Lænkholm, Anne-Vibeke, Grauslund, M., Jensen, M. B., Santoni Rugiu, Eric, Andersson, M. & Ewertz, M., Aug 2012, In: Annals of oncology : official journal of the European Society for Medical Oncology. 23, 8, p. 2034-2042 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 102813499
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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Research output: Contribution to journal › Journal article › Research › peer-review
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82
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The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer
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Genomic Analyses of Breast Cancer Progression Reveal Distinct Routes of Metastasis Emergence
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