Anne Tybjærg-Hansen
Clinical Professor
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Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease
Lundegaard, C., Tybjærg-Hansen, Anne, Grande, P. & Frikke-Schmidt, Ruth, 1 Dec 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. E500-10Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis
Stender, S., Frikke-Schmidt, R., Nordestgaard, Børge, Grande, P. & Tybjærg-Hansen, Anne, 2013, In: The Internet Journal of Internal Medicine. 273, 1, p. 59-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R., Nordestgaard, B. G., Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, Børge, 2009, In: JAMA - Journal of the American Medical Association. 301, 22, p. 2331-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
Jørgensen, A. B., Frikke-Schmidt, R., West, A. S., Grande, P., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: European Heart Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease
Juul, K., Tybjærg-Hansen, A., Marklund, S., Lange, Peter, Nordestgaard, B. G. & Tybjærg-Hansen, Anne, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 8, p. 858-64Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically reduced soluble epoxide hydrolase activity and risk of stroke and other cardiovascular disease
Lee, J., Dahl, M., Grande, P., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2010, In: Stroke. 41, 1, p. 27-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics of Coronary Artery Disease
McPherson, R. & Tybjærg-Hansen, Anne, 18 Feb 2016, In: Circulation Research. 118, 4, p. 564-578 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetisk betinget reduktion i antioxidativ beskyttelse og øget risiko for iskaemisk hjertesygdom--sekundaerpublikation
Juul, K., Tybjærg-Hansen, Anne, Marklund, S., Heegaard, N. H. H., Steffensen, R., Sillesen, H. H., Jensen, G. B. & Nordestgaard, Børge, 2005, In: Ugeskrift for Laeger. 167, 7, p. 767-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme--sekundaerpublikation
Tolstrup, J. S., Nordestgaard, B. G., Rasmussen, S., Tybjærg-Hansen, Anne & Gronbaek, M., 2008, In: Ugeskrift for læger. 170, 35, p. 2672-2675 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomet i kardiologien
Bundgård, Henning, Diness, Birgitte Rode, Tfelt-Hansen, Jacob, Henriksen, F. L., Eschen, O., Skovby, F., Havndrup, O., Jensen, H. K. & Tybjærg-Hansen, Anne, 2014, In: Ugeskrift for Laeger. 176, 46, 5 p., V06140376.Research output: Contribution to journal › Journal article › Research › peer-review
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Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Stevens, C. A. T., Lyons, A. R. M., Dharmayat, K. I., Freiberger, T., Hovingh, G. K., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar-Salinas, C. A., Alhabib, K. F., Alkhnifsawi, M., Almahmeed, W., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 31 others, , 2021, In: The Lancet. 398, 10312, p. 1713-1725 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glutathione S-transferases T1 and M1 and asthma risk in 10,000 individuals and in meta-analysis
Norskov, M., Dahl, Morten & Tybjærg-Hansen, Anne, 1 Sep 2013.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study
Haase, C. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Sep 2015, In: Diabetes. 64, 9, p. 3328-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, , 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy
Ellervik, Christina, Tybjærg-Hansen, Anne, Appleyard, M., Ibsen, H. & Nordestgaard, Børge, 1 Sep 2010, In: Journal of Internal Medicine. 268, 3, p. 252-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease
Johannsen, T. H., Kamstrup, P. R., Andersen, R. V., Jensen, G. B., Sillesen, Henrik, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1264-73 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in ABCC6 and risk of ischemic vascular disease
Hornstrup, L. S., Tybjærg-Hansen, Anne, Haase, C. L., Nordestgaard, Børge, Sillesen, H., Grande, P. & Frikke-Schmidt, R., 2011, In: Circulation: Cardiovascular Genetics. 4, 5, p. 534-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in Abcc6 and Risk of Ischemic Vascular Disease
Hornstrup, L. S., Tybjaerg-Hansen, A., Haase, C. L., Nordestgaard, Børge, Grande, P., Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 38 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase–Lowering Effect of a HSD17B13 Variant
Gellert-Kristensen, H., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Hepatology. 71, 1, p. 56-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High body mass index and cancer risk
Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High fat in blood and body and increased risk of clinically diagnosed non-alcoholic fatty liver disease in 105,981 individuals
Kyhl, L. K., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Nielsen, S. F., 2023, In: Atherosclerosis. 376, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol
Sethi, A. A., Sampson, M., Warnick, R., Muniz, N., Vaisman, B., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Remaley, A. T., 1 Jul 2010, In: Clinical Chemistry. 56, 7, p. 1128-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-throughput genotyping of copy number variation in glutathione S-transferases M1 and T1 using real-time PCR in 20,687 individuals
Norskov, M. S., Frikke-Schmidt, Ruth, Loft, Steffen & Tybjærg-Hansen, Anne, 2009, In: Clinical Biochemistry. 42, 3, p. 201-209 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society
Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G. F., Averna, M., Boileau, C., Borén, J., Catapano, A. L., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 11 others, , 21 Aug 2014, In: European Heart Journal. 35, 32, p. 2146-2157 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls
Zacho, J., Yazdanyar, S., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: International Journal of Cancer. 128, 3, p. 644-52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and Replication of Six Loci Associated With Gallstone Disease
Gellert-Kristensen, H., Dalila, N., Fallgaard Nielsen, S., Grønne Nordestgaard, B., Tybjærg-Hansen, Anne & Stender, S., Aug 2019, In: Hepatology. 70, 2, p. 597-609 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ikkefastende triglycerider og risiko for iskamisk apopleksi--sekundaerpublikation
Freiberg, J. J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 26, p. 2188-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ikkefastende triglycerider og risiko for iskæmisk apopleksi - sekundærpublikation
Freiberg, J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, Børge, 2009, In: Ugeskrift for læger. 171, p. 2188-2191Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study
Emanuelsson, F., Marott, S., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, Apr 2020, In: Diabetes Care. 43, 4, p. 894-902 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study
Emanuelsson, F., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Sep 2019, In: Journal of the American College of Cardiology. 74, 11, p. 1465-1476Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention
Juul Rasmussen, I., Rasmussen, K. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: European Heart Journal. 41, 41, p. 4024-4033 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of diet on ten-year absolute cardiovascular risk in a prospective cohort of 94 321 individuals: A tool for implementation of healthy diets
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: The Lancet Regional Health - Europe. 19, 100419.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis
Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503Research output: Contribution to journal › Journal article › Research › peer-review
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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving prediction of ischemic cardiovascular disease in the general population using apolipoprotein B: the Copenhagen City Heart Study
Benn, M., Nordestgaard, B., Jensen, G. B., Tybjaerg-Hansen, A., Tybjærg-Hansen, Anne, Benn, M. & Nordestgaard, Børge, 2007, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 3, p. 661-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts
Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study
Benfield, T., Ejrnæs, K., Juul, K., Ostergaard, C., Helweg-Larsen, J., Weis, N., Munthe-Fog, L., Kronborg, G., Andersen, M. R., Tybjærg-Hansen, A., Nordestgaard, B. G., Garred, P., Benfield, T., Ejrnaes, K., Juul, K., Andersen, C. Ø., Helweg-Larsen, J., Weis, N. M., Munthe-Fog, L., Kronborg, G. & 4 others, , 1 Jan 2010, In: Critical Care (Online Edition). 14, 2, p. R28Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome: a population-based study
Benfield, Thomas, Dahl, M., Nordestgaard, B. G., Tybjærg-Hansen, Anne & Dahl, M., 15 Nov 2005, In: Journal of Infectious Diseases. 192, 10, p. 1851-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Trinder, M., Wang, Y., Madsen, C. M., Ponomarev, T., Bohunek, L., Daisley, B. A., Kong, H. J., Blauw, L. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Wurfel, M. M., Russell, J. A., Walley, K. R., Rensen, P. C. N., Boyd, J. H. & Brunham, L. R., 2021, In: Circulation. 143, 9, p. 921–934Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
DBDS Genomic Consortium, D. G. C., 2024, (E-pub ahead of print) In: Nature Genetics. 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar, N., Butterworth, A. S., Freitag, D. F., Gregson, J., Willeit, P., Gorman, D. N., Gao, P., Saleheen, D., Rendon, A., Nelson, C. P., Braund, P. S., Hall, A. S., Chasman, D. I., Tybjærg-Hansen, A., Chambers, J. C., Benjamin, E. J., Franks, P. W., Clarke, R., Wilde, A. A. M., Trip, M. D. & 31 others, , 31 Mar 2012, In: Lancet. 379, 9822, p. 1205-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals
Haase, C. L., Tybjærg-Hansen, Anne, Ali Qayyum, A., Schou, J., Nordestgaard, Børge & Frikke-Schmidt, R., Feb 2012, In: Journal of Clinical Endocrinology and Metabolism. p. E248-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals
Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Leukotriene C-4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, Morten, Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., Apr 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-586Research output: Contribution to journal › Journal article › Research › peer-review
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Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, M., Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid-related markers and cardiovascular disease prediction
Di Angelantonio, E., Gao, P., Pennells, L., Kaptoge, S., Caslake, M., Thompson, A., Butterworth, A. S., Sarwar, N., Wormser, D., Saleheen, D., Ballantyne, C. M., Psaty, B. M., Sundström, J., Ridker, P. M., Nagel, D., Gillum, R. F., Ford, I., Ducimetiere, P., Kiechl, S., Koenig, W. & 31 others, , 2012, In: J A M A: The Journal of the American Medical Association. 307, 23, p. 2499-506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease: A Note on Mendelian Randomization Studies
Würtz, P., Kangas, A. J., Soininen, P., Lehtimäki, T., Kähönen, M., Viikari, J. S., Raitakari, O. T., Järvelin, M., Davey Smith, G., Ala-Korpela, M., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2013, In: Journal of the American College of Cardiology. 62, 20, p. 1906-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
Research output: Contribution to journal › Journal article › Research › peer-review
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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