Anne Tybjærg-Hansen

Anne Tybjærg-Hansen

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. Published

    Screening of Three Novel Candidate Genes in Arrhythmogenic Right Ventricular Cardiomyopathy

    Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Genetic Testing and Molecular Biomarkers. 15, 4, p. 267-71 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population

    Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

    Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles

    Christoffersen, C., Benn, M., Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Dahlbäck, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research. 53, 10, p. 2198-204 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Xanthelasmas Predict Risk of Ischemic Heart Disease, Myocardial Infarction, and Overall Death in the General Population

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 33 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  7. Published

    Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study

    Christoffersen, M., Frikke-Schmidt, R., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: B M J. 343, p. d5497

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Polygenic risk scores: how much do they add?

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 4 Mar 2014, In: Circulation Research. 129, 9, p. 990-998 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications

    Christoffersen, M. & Tybjærg-Hansen, Anne, Jan 2016, In: Ageing Research Reviews. 25, p. 24-41 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Targeting IL-6 in patients at high cardiovascular risk

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: The Lancet. 397, 10289, p. 2025-2027 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published

    Novel genes in LDL metabolism: a comprehensive overview

    Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Polygenic Risk Scores

    Christoffersen, M. & Tybjærg-Hansen, Anne, 2022, Cardiovascular Risk Assessment in Primary Prevention. Humana Press, p. 429-446 (Contemporary Cardiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  14. Published

    Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses

    Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function

    Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., Van Den Bosch, M. T., Teasdale, J. E., Jones, M., Bond, M., Harper, M. T., Falk, L., Groom, A., Hazell, G. G. J., Paternoster, L., Munafò, M. R., Nordestgaard, B. G., Tybjærg-Hansen, A., Bojesen, S. E., Relton, C., Min, J. L. & 4 others, Davey Smith, G., Mumford, A. D., Poole, A. W. & Timpson, N. J., 2022, In: Circulation Research. 130, 3, p. 384-400 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The European heart journal: Leading the fight to reduce the global burden of cardiovascular disease

    Crea, F., Badimon, L., Berry, C., de Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjærg-Hansen, Anne & EHJ Editorial Board, E. E. B., 2020, In: European Heart Journal. 41, 33, p. 3113-3116 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  17. Published

    The European Heart Journal: fulfilling the mission

    Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C. & Tybjærg-Hansen, Anne, 2022, In: European Heart Journal. 43, 23, p. 2181-2184 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  18. Published

    Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

    Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G. F., Averna, M., Boileau, C., Borén, J., Catapano, A. L., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 11 others, Masana, L., Pajukanta, P., Parhofer, K. G., Ray, K. K., Stalenhoef, A. F. H., Stroes, E., Taskinen, M., Wiegman, A., Wiklund, O., Chapman, M. J. & European Atherosclerosis Society Consensus Panel on Familial Hypercholesterolaemia, E. A. S. C. P. O. F. H., 21 Aug 2014, In: European Heart Journal. 35, 32, p. 2146-2157 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    ΔF508 heterozygosity in cystic fibrosis and susceptibility to asthma

    Dahl, Morten, Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 1998, In: Lancet.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Elevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary disease

    Dahl, M., Tybjærg-Hansen, Anne, Vestbo, J., Lange, Peter & Nordestgaard, Børge, 15 Sep 2001, In: American Journal of Respiratory and Critical Care Medicine. 164, 6, p. 1008-11 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, Morten, Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, Anne & Nordestgaard, B. G., Mar 2011, In: Thorax. 66, 3, p. 197-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Beta2-Adrenergic Receptor Polymorphism Associated With Reduced Lung Function In Two Large Populations

    Dahl, Morten, Thomsen, M., Nordestgaard, Børge, Sethi, A. & Tybjærg-Hansen, Anne, May 2011, C22. PATHOBIOLOGY OF COPD: LESSONS FROM INFLAMMATORY MECHANISMS AND GENOMIC STUDIES.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  24. Published

    Nose and blood pressure

    Dahl, M., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Lange, Peter & Vestbo, J., 15 Jan 2004, In: American Journal of Respiratory and Critical Care Medicine. 169, 2, p. 318; author reply 319

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, M., Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Thorax. 66, 3, p. 197-204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Blood pressure, risk of ischemic cerebrovascular and ischemic heart disease, and longevity in alpha(1)-antitrypsin deficiency: the Copenhagen City Heart Study

    Dahl, M., Tybjærg-Hansen, Anne, Sillesen, Henrik, Jensen, G., Steffensen, R. & Nordestgaard, Børge, 11 Feb 2003, In: Circulation. 107, 5, p. 747-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Risk of ischemic heart and ischemic cerebrovascular disease is not increased in S, Z, and 11478A alpha1-antitrypsin carriers of the Copenhagen City Heart Study

    Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Nov 2003, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 11, p. e55; author reply e55

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Morbiditet og mortalitet hos personer med mannosebindende lektinmangel. Osterbroundersøgelsen

    Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 6 Dec 2004, In: Ugeskrift for Laeger. 166, 50, p. 4606-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Baerere af cystisk fibrose har øget risiko for asthma. Osterbroundersøgelsen

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 9 Aug 1999, In: Ugeskrift for Laeger. 161, 32, p. 4507-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

    Dahl, M., Vestbo, J., Zacho, J., Lange, Peter, Tybjærg-Hansen, A., Nordestgaard, B. G., Dahl, M., Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Thorax. 66, 3, p. 197-204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Molecular diagnosis of intermediate and severe alpha(1)-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals

    Dahl, M., Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, Jan 2001, In: Clinical Chemistry. 47, 1, p. 56-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals

    Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  33. Published

    Cystic fibrosis ΔF508 heterozygotes, smoking, and reproduction: studies of 9141 individuals from a general population sample

    Dahl, M., Tybjærg-Hansen, Anne, Wittrup, H. H., Lange, Peter & Nordestgaard, Børge, 1998, In: Genomics. 50, 1, p. 89-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion

    Dahl, M., Nordestgaard, Børge, Lange, Peter & Tybjærg-Hansen, Anne, May 2001, In: Journal of Allergy and Clinical Immunology. 107, 5, p. 818-23 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease

    Dahl, M., Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Asthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based study

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 2005, In: Respiratory Research. 6, p. 113

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease

    Dahl, Morten, Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 1 Feb 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-255

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    DeltaF508 heterozygosity in cystic fibrosis and susceptibility to asthma

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 27 Jun 1998, In: Lancet. 351, 9120, p. 1911-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A population-based study of morbidity and mortality in mannose-binding lectin deficiency

    Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 17 May 2004, In: Journal of Experimental Medicine. 199, 10, p. 1391-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Change in lung function and morbidity from chronic obstructive pulmonary disease in alpha1-antitrypsin MZ heterozygotes: A longitudinal study of the general population

    Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter, Vestbo, J. & Nordestgaard, Børge, 19 Feb 2002, In: Annals of Internal Medicine. 136, 4, p. 270-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals

    Dalila, N., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: Atherosclerosis. 376, p. 26-33 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

    Dewey, F. E., Gusarova, V., Dunbar, R. L., O'Dushlaine, C. T., Schurmann, C., Gottesman, O., McCarthy, S., Van Hout, C. V., Bruse, S., Dansky, H. M., Leader, J. B., Murray, M. F., Ritchie, M. D., Kirchner, H. L., Habegger, L., Lopez, A., Penn, J., Zhao, A., Shao, W., Stahl, N. & 37 others, Murphy, A. J., Hamon, S., Bouzelmat, A., Zhang, R., Shumel, B., Pordy, R., Gipe, D., Herman, G. A., Sheu, W. H., Lee, I., Liang, K., Guo, X., Rotter, J. I., Chen, Y. I., Kraus, W. E., Shah, S. H., Damrauer, S., Small, A., Rader, D. J., Wulff, A. B., Nordestgaard, Børge, Tybjærg-Hansen, Anne, van den Hoek, A. M., Princen, H. M. G., Ledbetter, D. H., Carey, D. J., Overton, J. D., Reid, J. G., Sasiela, W. J., Banerjee, P., Shuldiner, A. R., Borecki, I. B., Teslovich, T. M., Yancopoulos, G. D., Mellis, S. J., Gromada, J. & Baras, A., Jul 2017, In: New England Journal of Medicine. 377, 3, p. 211-221

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Lipid-related markers and cardiovascular disease prediction

    Di Angelantonio, E., Gao, P., Pennells, L., Kaptoge, S., Caslake, M., Thompson, A., Butterworth, A. S., Sarwar, N., Wormser, D., Saleheen, D., Ballantyne, C. M., Psaty, B. M., Sundström, J., Ridker, P. M., Nagel, D., Gillum, R. F., Ford, I., Ducimetiere, P., Kiechl, S., Koenig, W. & 31 others, Dullaart, R. P. F., Assmann, G., D'Agostino, R. B., Dagenais, G. R., Cooper, J. A., Kromhout, D., Onat, A., Tipping, R. W., Gómez-de-la-Cámara, A., Rosengren, A., Sutherland, S. E., Gallacher, J., Fowkes, F. G. R., Casiglia, E., Hofman, A., Salomaa, V., Barrett-Connor, E., Clarke, R., Brunner, E., Jukema, J. W., Simons, L. A., Sandhu, M., Wareham, N. J., Khaw, K., Kauhanen, J., Salonen, J. T., Howard, W. J., Nordestgaard, Børge, Wood, A. M., Emerging Risk Factors Collaboration, E. R. F. C. & Tybjærg-Hansen, Anne, 2012, In: J A M A: The Journal of the American Medical Association. 307, 23, p. 2499-506 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

    Do, R., Stitziel, N. O., Won, H-H., Jørgensen, A. B., Duga, S., Angelica Merlini, P., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., Lange, L. A., Peloso, G. M., Auer, P. L., Girelli, D., Martinelli, N., Farlow, D. N., DePristo, M. A., Roberts, R. & 31 others, Stewart, A. F. R., Saleheen, D., Danesh, J., Epstein, S. E., Sivapalaratnam, S., Hovingh, G. K., Kastelein, J. J., Samani, N. J., Schunkert, H., Erdmann, J., Shah, S. H., Kraus, W. E., Davies, R., Nikpay, M., Johansen, C. T., Wang, J., Hegele, R. A., Hechter, E., Marz, W., Kleber, M. E., Huang, J., Johnson, A. D., Li, M., Burke, G. L., Gross, M., Liu, Y., Assimes, T. L., Heiss, G., Lange, E. M., Tybjærg-Hansen, Anne & NHLBI Exome Sequencing Project, N. E. S. P., 5 Feb 2015, In: Nature. 518, 7537, p. 102-6, 4 unpag. pages 9 p.

    Research output: Contribution to journalLetterResearchpeer-review

  45. Published

    Risk of cancer by ATM missense mutations in the general population

    Dombernowsky, S. L., Weischer, M., Allin, K. H., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Oncology. 26, 18, p. 3057-62 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer

    Dombernowsky, S. L., Weischer, M., Freiberg, J. J., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2009, In: Cancer Epidemiology, Biomarkers & Prevention. 18, 8, p. 2339-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Modifications to the Patient Rule-Induction Method that utilize non-additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease

    Dyson, G., Frikke-Schmidt, Ruth, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Sing, C. F., 2009, In: Genetic Epidemiology. 33, 4, p. 317-24 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Blood Chimerism in Dizygotic Monochorionic Twins During 5 Years Observation

    Dziegiel, Morten Hanefeld, Hansen, M. H., Haedersdal, S., Barrett, A. N., Rieneck, K., Main, Katharina Maria, Tybjærg-Hansen, Anne & Clausen, F. B., 2017, In: American Journal of Transplantation. 17, 10, p. 2728-2732

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Risk of cancer by transferrin saturation levels and haemochromatosis genotype: population-based study and meta-analysis

    Ellervik, Christina, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ellervik, Christina, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 1, p. 51-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy

    Ellervik, Christina, Tybjærg-Hansen, Anne, Appleyard, M., Ibsen, H. & Nordestgaard, Børge, 1 Sep 2010, In: Journal of Internal Medicine. 268, 3, p. 252-64 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 924951