Andreas Mæchel Fritzen

Andreas Mæchel Fritzen

Associate Professor

ORCID: 0000-0001-8793-9739

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  1. Published

    5´AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, J., Christiansen, M. L. B., Biensø, R. S., Dyck, J. R. B., Pilegaard, Henriette & Kiens, Bente, 2015, In: Journal of Physiology. 593, 21, p. 4765-4780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Adaptations in mitochondrial enzymatic activity occurs independent of genomic dosage in response to aerobic exercise training and deconditioning in human skeletal muscle

    Fritzen, Andreas Mæchel, Thøgersen, F. B., Thybo, K., Vissing, C. R., Krag, T. O., Ruiz-Ruiz, C., Risom, L., Wibrand, F., Høeg, L. D., Kiens, Bente, Duno, M., Vissing, John & Jeppesen, T. D., 2019, In: Cells. 8, 3, 16 p., 237.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2

    Fritzen, Andreas Mæchel, Domingo-Espín, J., Lundsgaard, Anne-Marie, Kleinert, Maximilian, Israelsen, I., Carl, Christian Strini, Nicolaisen, T. S., Kjøbsted, Rasmus, Jeppesen, J. F., Wojtaszewski, Jørgen F P, Lagerstedt, J. O. & Kiens, Bente, 2020, In: Molecular Metabolism. 35, 11 p., 100949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Atlas of exercise-induced brain activation in mice

    Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cancer causes metabolic perturbations associated with reduced insulin-stimulated glucose uptake in peripheral tissues and impaired muscle microvascular perfusion

    Han, X., Raun, Steffen Henning, Carlsson, Michala, Sjøberg, K. A., Henriquez-Olguín, Carlos, Ali, Mona Sadek, Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Møller, Lisbeth L V, Li, Z., Li, J., Jensen, Thomas Elbenhardt, Kiens, Bente & Sylow, Lykke, 2020, In: Metabolism - Clinical and Experimental. 105, 14 p., 154169.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Sjøberg, K. A., Myrmel, L. S., Madsen, L., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2017, In: Molecular Metabolism. 6, 1, p. 22-29 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain

    Jensen, Benjamin Anderschou Holbech, Nielsen, Thomas Svava, Fritzen, Andreas Mæchel, Holm, J. B., Fjære, E., Serup, A. K. L., Borkowski, K., Risis, S., Pærregaard, S. I., Søgaard, I., Poupeau, A. A. G., Poulsen, M., Ma, Tao, Sina, C., Kiens, Bente, Madsen, L., Kristiansen, Karsten & Treebak, Jonas Thue, 2016, In: Metabolism. 65, 12, p. 1706-1719 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Dietary fuels in athletic performance

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie & Kiens, Bente, 2019, In: Annual Review of Nutrition. 39, p. 45-73 29 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Effect of aerobic exercise training and deconditioning on oxidative capacity and muscle mitochondrial enzyme machinery in young and elderly individuals

    Fritzen, Andreas Mæchel, Andersen, S. P., Qadri, K. A. N., Thøgersen, Frank Dyrehauge, Krag, T., Ørngreen, M. C., Vissing, John & Jeppesen, T. D., 2020, In: Journal of Clinical Medicine. 9, 10, 15 p., 3113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Emerging Roles of AMP-Activated Protein Kinase: The Role of AMPK in Regulatin of Substrate Utilisation During and After Acute Exercise, Adipose Tissue Metabolism During Weight Loss, and Autophagy in Skeletal Muscle During Acute Exercise

    Fritzen, Andreas Mæchel, 2016, Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen. 138 p.

    Research output: Book/Report › Ph.D. thesis › Research

  12. Published

    Exercise physiology in men and women

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel & Kiens, Bente, 2017, Principles of Gender-Specific Medicine: Gender in the Genomic Era. Legato, M. J. (ed.). 3. ed. Amsterdam: Academic Press, p. 526-542 18 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  13. Published

    Exercise physiology in women and men

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel & Kiens, Bente, 2023, Principles of Gender-Specific Medicine: Sex and Gender-Specific Biology in the Postgenomic Era. Legato, M. J. (ed.). 4 ed. Elsevier, p. 573-587 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  14. Published

    FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis

    Mottillo, E. P., Desjardins, E. M., Fritzen, Andreas Mæchel, Zou, V. Z., Crane, J. D., Yabut, J. M., Kiens, Bente, Erion, D. M., Lanba, A., Granneman, J. G., Talukdar, S. & Steinberg, G. R., 2017, In: Molecular Metabolism. 6, 6, p. 471-481 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Fatty acid type-specific regulation of SIRT1 does not affect insulin sensitivity in human skeletal muscle

    Fritzen, Andreas Mæchel, Lundsgaard, Anne-Marie, Jeppesen, J. F., Sjøberg, K. A., Høeg, L. D., Deleuran, H. H., Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: F A S E B Journal. 33, 4, p. 5510-5519 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. E-pub ahead of print

    Genetics and diet shape the relationship between islet function and whole-body metabolism

    Yau, B., Madsen, S., Healy, M. E., Cooke, K. C., Fritzen, Andreas Mæchel, Thorius, I. H., Stöckli, J., James, D. E. & Kebede, M. A., 3 Apr 2024, (E-pub ahead of print) In: American journal of physiology. Endocrinology and metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Growth factor-dependent and -independent activation of mTORC2

    Knudsen, Jonas Roland, Fritzen, Andreas Mæchel, James, D. E., Jensen, Thomas Elbenhardt, Kleinert, Maximilian & Richter, Erik A., 2020, In: Trends in Endocrinology and Metabolism. 31, 1, p. 13-24 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Human Paneth cell α-defensin-5 treatment reverses dyslipidemia and improves glucoregulatory capacity in diet-induced obese mice

    Larsen, I. S., Fritzen, Andreas Mæchel, Carl, Christian Strini, Agerholm, M., Damgaard, Mads Vargas, Holm, J. B., Marette, A., Nordkild, P., Kiens, Bente, Kristiansen, Karsten, Wehkamp, J. & Jensen, Benjamin Anderschou Holbech, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 1, p. E42-E52 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Insulin tolerance test under anaesthesia to measure tissue-specific insulin-stimulated glucose disposal

    Fazakerley, D. J., Fritzen, Andreas Mæchel, Nelson, M. E., Thorius, I. H., Cooke, K. C., Humphrey, S. J., Cooney, G. J. & James, D. E., 2019, In: Bio-protocol. 9, 2, 13 p., e3146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    LKB1 regulates lipid oxidation during exercise independently of AMPK

    Jeppesen, J. F., Maarbjerg, S. J., Jordy, A. B., Fritzen, Andreas Mæchel, Pehmøller, C., Sylow, Lykke, Serup, A. K. L., Jessen, N., Thorsen, K., Prats Gavalda, Clara, Qvortrup, Klaus, Dyck, J. R. B., Hunter, R. W., Sakamoto, Kei, Thomson, D. M., Schjerling, Peter, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2013, In: Diabetes. 62, 5, p. 1490-1499 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice

    Kleinert, Maximilian, Parker, B. L., Fritzen, Andreas Mæchel, Knudsen, Jonas Roland, Jensen, Thomas Elbenhardt, Kjøbsted, Rasmus, Sylow, Lykke, Ruegg, M. A., James, D. E. & Richter, Erik A., 2017, In: Journal of Physiology. 595, 14, p. 4845-4855 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Measurement of skeletal muscle glucose uptake in mice in response to acute treadmill running

    Møller, Lisbeth L V, Raun, Steffen Henning, Fritzen, Andreas Mæchel & Sylow, Lykke, 2022, In: Journal of Biological Methods. 9, 3, 13 p., e162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel & Kiens, Bente, 2018, In: Trends in Endocrinology and Metabolism. 29, 1, p. 18-30 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

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