Hans K Hasselbalch
Clinical Professor
Department of Clinical Medicine
Køgevej 7 - 13, 4000 Roskilde
Member of:
Internal Medicine: Haematology
- 2024
- Published
JAK2V617F drives gut microbiota differences in patients with myeloproliferative neoplasms
Eickhardt-Dalbøge, C. S., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Lilje, B., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Sørensen, A. L., Ellervik, Christina, Olsen, L. R., Christensen, J. J. E., Nielsen, X. C., Hasselbalch, Hans Carl & Ingham, A. C., 2024, In: European Journal of Haematology. 112, 5, p. 776-787 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CHIP-JAK2V617F, chronic inflammation, abnormal megakaryocyte morphology, organ failure, and multimorbidties
Hasselbalch, Hans Carl, Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina & Wienecke, Troels, 2024, In: Blood advances. 8, 3, p. 681-682 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Neutrophil-to-lymphocyte ratio and all-cause mortality with and without myeloproliferative neoplasms-a Danish longitudinal study
Larsen, Morten Kranker, Skov, V., Kjær, L., Eickhardt-Dalbøge, C. S., Knudsen, T. A., Kristiansen, M. H., Sørensen, A. L., Wienecke, Troels, Andersen, M., Ottesen, J. T., Gudmand-Høyer, J., Snyder, J. A., Andersen, M. P., Torp-Pedersen, Christian, Poulsen, Henrik Enghusen, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2024, In: Blood Cancer Journal. 14, 1, 12 p., 28.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms
Gotfredsen, K., Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 11 Mar 2023, In: Scientific Reports. 13, 1, p. 4077 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2
Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Ellervik, Christina, Larsen, Morten Kranker, Kjær, L., Skov, V., Hasselbalch, Hans Carl & Ottesen, J. T., 2023, In: Cancer Medicine. 12, 4, p. 4218-4226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial
Grauslund, J. H., Holmström, M. O., Martinenaite, E., Lisle, T. L., Glöckner, H. J., Fassi, Daniel El , Klausen, U., Mortensen, R. E. J., Jørgensen, N., Kjær, L., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1117466.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Case Report: First longitudinal study of a patient with CALR positive clonal hematopoiesis of indeterminate potential developing into pre-fibrotic myelofibrosis
Kjær, L., Skov, V., Larsen, Morten Kranker, Boklund, T. I., Andersen, M., Kefala, Maria, Knudsen, T. A., Schjellerup Eickhardt-Dalbøge, C., Stiehl, T., Gudmand-Høyer, J., Snyder, J., Holmström, M., Andersen, M. H., Ottesen, J. T., Ellervik, Christina & Hasselbalch, Hans Carl, 2023, In: Frontiers in Oncology. 13, 8 p., 1176173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated white blood cell counts in ischemic stroke patients are associated with increased mortality and new vascular events
Vo, T. P., Kristiansen, M. H., Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Frontiers in Neurology. 14, 8 p., 1232557.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Event-free survival in patients with polycythemia vera treated with ropeginterferon alfa-2b versus best available treatment
the PROUD-PV Study Group, T. P. S. G., 2023, In: Leukemia. 37, 10, p. 2129-2132 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
High JAK2V617F variant allele frequency is associated with coronary artery but not aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms
Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2023, In: European Journal of Haematology. 111, 3, p. 400-406 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon alpha-2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms
Massarenti, Laura, Knudsen, T. A., Enevold, Christian, Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, 2023, In: British Journal of Haematology. 202, 2, p. 318-327 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study
Kristiansen, M. H., Kjær, L., Skov, V., Larsen, Morten Kranker, Ellervik, Christina, Hasselbalch, Hans Carl & Wienecke, Troels, 2023, In: Blood advances. 7, 19, p. 5825-5834 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pronounced gut microbiota signatures in patients with JAK2V617F-positive essential thrombocythemia
Eickhardt-Dalbøge, C. S., Ingham, A. C., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Andersen, L. O., Larsen, Morten Kranker, Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, Christina, Olsen, L. R., Hasselbalch, Hans Carl, Elmer Christensen, J. J. & Nielsen, X. C., 2023, In: Microbiology Spectrum. 11, 5, 19 p., e0066223.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms
Hasselbalch, Hans Carl, Junker, P., Skov, V., Kjær, L., Knudsen, T. A., Larsen, Morten Kranker, Holmström, M. O., Andersen, Mads Hald, Jensen, C., Karsdal, M. A. & Willumsen, N., 2023, In: Cancers. 15, 17, 47 p., 4323.Research output: Contribution to journal › Review › Research › peer-review
- Published
The gut microbiota in patients with polycythemia vera is distinct from that of healthy controls and varies by treatment
Eickhardt-dalbøge, C. S., Ingham, A. C., Andersen, L. O., Nielsen, H. V., Fuursted, K., Stensvold, C. R., Larsen, M. K., Kjær, L., Christensen, S. F., Knudsen, T. A., Skov, V., Ellervik, C., Olsen, L. R., Hasselbalch, Hans Carl, Nielsen, X. C. & Christensen, J. J. E., 2023, In: Blood advances. 7, 13, p. 3326-3337 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic cancer vaccination against mutant calreticulin in myeloproliferative neoplasms induces expansion of specific T cells in the periphery but specific T cells fail to enrich in the bone marrow
Holmström, M. O., Andersen, M., Traynor, S., Ahmad, S. M., Lisle, T. L., Handlos Grauslund, J., Skov, V., Kjær, L., Ottesen, J. T., Gjerstorff, M. F., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1240678.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers
Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, Jun 2022, In: PLoS ONE. 17, 6, 16 p., e0269960.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b
PROUD-PV Study Grp, P. S. G., May 2022, In: Leukemia. 36, 5, p. 1408-1411 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine
Gigoux, M., Holmström, M. O., Zappasodi, R., Park, J. J., Pourpe, S., Bozkus, C. C., Mangarin, L. M. B., Redmond, D., Verma, S., Schad, S., George, M. M., Venkatesh, D., Ghosh, A., Hoyos, D., Molvi, Z., Kamaz, B., Marneth, A. E., Duke, W., Leventhal, M. J., Jan, M. & 23 others, , 2022, In: Science Translational Medicine. 14, 649, eaba4380.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clonal haematopoiesis of indeterminate potential and impaired kidney function—A Danish general population study with 11 years follow-up
Larsen, Morten Kranker, Skov, V., Kjær, L., Møller-Palacino, N. A., Pedersen, R. K., Andersen, M., Ottesen, J. T., Cordua, S., Poulsen, Henrik Enghusen, Dahl, Morten, Knudsen, T. A., Eickhardt-Dalbøge, C. S., Koschmieder, S., Pedersen, K. M., Çolak, Y., Bojesen, Stig Egil, Nordestgaard, Børge, Stiehl, T., Hasselbalch, Hans Carl & Ellervik, Christina, 2022, In: European Journal of Haematology. 109, 5, p. 576-585 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coronary artery- and aortic valve calcifications in patients with Philadelphia-negative myeloproliferative neoplasms
Solli, C. N., Chamat-Hedemand, S., Elming, H., Ngo, A., Kjær, L., Skov, V., Sørensen, A. L., Ellervik, Christina, Fuchs, A., Sigvardsen, P. E., Kühl, J. T., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Hasselbalch, Hans Carl & Bruun, Niels Eske, 2022, In: International Journal of Cardiology. 364, p. 112-118 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic profiling of a randomized trial of interferon-a vs hydroxyurea in MPN reveals mutation-specific responses
Knudsen, T. A., Skov, V., Stevenson, K., Werner, L., Duke, W., Laurore, C., Gibson, C. J., Nag, A., Thorner, A. R., Wollison, B., Hansen, D. L., Ellervik, C., Fassi, D. E., de Stricker, K., Ocias, L. F., Brabrand, M., Bjerrum, O. W., Overgaard, U. M., Frederiksen, M., Kristensen, T. K. & 12 others, , 2022, In: Blood advances. 6, 7, p. 2107-2119 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Healthcare resource utilization in patients with myeloproliferative neoplasms: A Danish nationwide matched cohort study
Christensen, S. F., Svingel, L. S., Kjaersgaard, A., Stenling, A., Darvalics, B., Paulsson, B., Andersen, Christen Bertel L, Christiansen, C. F., Stentoft, J., Starklint, J., Severinsen, M. T., Clausen, M. B., Hilsoe, M. H., Hasselbalch, Hans Carl, Frederiksen, H., Mikkelsen, E. M. & Bak, M., 2022, In: European Journal of Haematology. 109, 5, p. 526-541 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms favorably impacts deregulation of oxidative stress genes and antioxidative defense mechanisms
Skov, V., Thomassen, M., Kjær, L., Ellervik, Christina, Larsen, Morten Kranker, Knudsen, T. A., Kruse, T. A. & Hasselbalch, Hans Carl, 2022, In: PLoS ONE. 17, 6 , e0270669.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients With Myeloproliferative Neoplasms Harbor High Frequencies of CD8 T Cell-Platelet Aggregates Associated With T Cell Suppression
Carnaz Simões, A. M., Holmström, M. O., Aehnlich, P., Rahbech, Anne, Radziwon-Balicka, A., Zamora, C., Wirenfeldt Klausen, T., Skov, V., Kjær, L., Ellervik, Christina, Fassi, Daniel El , Vidal, S., Hasselbalch, Hans Carl, Andersen, Mads Hald & thor Straten, P., 2022, In: Frontiers in Immunology. 13, 866610.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 2849472
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A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
154
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Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
137
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Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development
Research output: Contribution to journal › Journal article › Research › peer-review
Published