Kirsten Grønbæk
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
- 2016
- Published
Lenalidomide-bendamustine-rituximab in untreated mantle cell lymphoma > 65 years with untreated mantle cell lymphoma
Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Grønbæk, Kirsten, Sundberg, J., Pedersen, L. B., Ralfkiær, E., Karjalainen-Lindsberg, M., Sundström, C., Ehinger, M., Geisler, C. & Jerkeman, M., 2016, In: Blood. 128, 14, p. 1814-1820Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations
Aslan, D., Garde, C., Nygaard, M. K., Helbo, A. S., Dimopoulos, K., Hansen, Jakob Werner, Severinsen, M. T., Treppendahl, M. B., Sjö, Lene Dissing, Grønbæk, Kirsten & Sommer Kristensen, L., 2016, In: OncoTarget. 7, 9, p. 9951-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING
Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator
Husby, S., Ralfkiaer, U., Garde, C., Zandi, R., Ek, S., Kolstad, A., Jerkeman, M., Laurell, A., Räty, R., Pedersen, L. B., Pedersen, A., Ehinger, M., Sundström, C., Karjalainen-Lindsberg, M-L., Delabie, J., Clasen-Linde, E., Brown, P. D. N., Cowland, J. B., Workman, C. T., Geisler, C. H. & 1 others, , 23 Apr 2015, In: Blood. 125, 17, p. 2669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Expression of miR-155 and miR-21 in Tumor and Stroma Cells in Diffuse Large B-Cell Lymphoma
Munch-Petersen, H. D., Ralfkiaer, U., Sjö, Lene Dissing, Hother, C., Asmar, F., Nielsen, B. S., Brown, P., Ralfkiaer, E. & Grønbæk, Kirsten, Mar 2015, In: Applied Immunohistochemistry & Molecular Morphology. 23, 3, p. 188-195 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of PRDM11 promotes MYC-driven lymphomagenesis
Fog-Tonnesen, C. K., Asmar, F., Côme, Christophe Roger Michel, Jensen, K. T., Johansen, Jens Vilstrup, Bou Kheir, T., Jacobsen, L., Friis, C., Louw, A., Rosgaard, L., Øbro, N. F., Marquart, Hanne Vibeke Hansen, Anthonsen, K., Braat, A. K., van Lohuizen, M., Ralfkiaer, E., Grønbæk, Kirsten & Lund, Anders H., 19 Feb 2015, In: Blood. 125, 8, p. 1272-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allele-Specific DNA Methylation Detection by Pyrosequencing®
Sommer Kristensen, L., Johansen, Jens Vilstrup & Grønbæk, Kirsten, 2015, Pyrosequencing: Methods and Protocols. Lehmann, U. & Tost, J. (eds.). Vol. 1315. p. 271-89 19 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Development and blind clinical validation of a microRNA based predictor of response to treatment with R-CHO(E)P in DLBCL
Knudsen, S., Hother, C., Grønbæk, Kirsten, Jensen, T., Hansen, A., Mazin, W., Dahlgaard, J., Møller, M. B., Ralfkiær, E. & Brown, P. D. N., 2015, In: P L o S One. 10, 2, 15 p., e0115538.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients
Helbo, A. S., Treppendahl, M. B., Aslan, D., Dimopoulos, K., Nandrup-Bus, C., Holm, M. S., Andersen, M. K., Liang, G., Sommer Kristensen, L. & Grønbæk, Kirsten, 2015, In: Genes. 6, 4, p. 977-90 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation
mxz703, mxz703, Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome
Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma
Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation
Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., Christophersen, N. S., Christensen, L. L., Borre, M., Sørensen, K. D., Andersen, L. D., Andersen, C. L., Hulleman, E., Wurdinger, T., Ralfkiær, E., Helin, K., Grønbæk, K., Orntoft, T., Waszak, S. M., Dahan, O. & 3 others, , 11 Sep 2014, In: Cell. 158, 6, p. 1281-92 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat
Andersen, C. L., Bjørn, M. E., McMullin, M. F., Harrison, C., Samuelsson, J., Ejerblad, E., Zweegman, S., Fernandes, S., Bareford, D., Knapper, S., Löfvenberg, E., Linder, O., Andreasson, B., Ahlstrand, E., Jensen, M. K., Bjerrum, O. W., Vestergaard, H., Larsen, H., Klausen, T. W., Mourits-Andersen, T. & 5 others, , Jul 2014, In: Leukemia Research. 38, 7, p. 816-821 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma – a Nordic Lymphoma Group study
Nordström, L., Sernbo, S., Eden, P., Grønbæk, Kirsten, Kolstad, A., Räty, R., Karjalainen, M., Geisler, C., Ralfkiaer, E., Sundström, C., Laurell, A., Delabie, J., Ehinger, M., Jerkeman, M. & Ek, S., Jul 2014, In: British Journal of Haematology. 166, 1, p. 98-108 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome?
Asmar, F., Hother, C., Kulosman, G., Treppendahl, M. B., Nielsen, H. M., Ralfkiaer, U., Pedersen, A., Møller, M. B., Ralfkiaer, E., de Nully Brown, P. & Grønbæk, Kirsten, 15 Apr 2014, In: OncoTarget. 5, 7, p. 1912-25 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting response to epigenetic therapy
Treppendahl, M. B., Sommer Kristensen, L. & Grønbæk, Kirsten, Jan 2014, In: The Journal of Clinical Investigation. 124, 1, p. 47-55 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies
Gang, A. O., Frøsig, T. M., Brimnes, M. K., Lyngaa, R., Treppendahl, M. B., Grønbæk, Kirsten, Dufva, I. H., Straten, P. T. & Hadrup, S. R., 2014, In: Blood Cancer Journal. 4, 3, p. 1-9 9 p., e197.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia
Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma
Kristensen, L. S., Asmar, F., Dimopoulos, K., Nygaard, M. K., Aslan, D., Hansen, Jakob Werner, Ralfkiaer, E. & Grønbæk, Kirsten, 2014, In: OncoTarget. 5, 20, p. 9798-810 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
Holm, M., Dybedahl, I., Holm, M., Karimi, M., Brandefors, L., Garelius, H., Grövdal, M., Dufva, I. H., Grønbæk, Kirsten, Jansson, M., Marcher, C., Nilsson, L., Kittang, A. O., Porwit, A., Saft, L., Möllgård, L. & Hellström-Lindberg, E., 2014, In: Pediatric Blood & Cancer. 4, 3, p. 1-7 7 p., e189.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma
Kolstad, A., Laurell, A., Jerkeman, M., Grønbæk, K., Elonen, E., Räty, R., Pedersen, L. B., Loft, A., Bogsrud, T. V., Kimby, E., Hansen, P. B., Fagerli, U-M., Nilsson-Ehle, H., Lauritzsen, G. F., Lehmann, A. K., Sundstrom, C., Karjalainen-Lindsberg, M-L., Ralfkiaer, E., Ehinger, M., Delabie, J. & 7 others, , 2014, In: Blood. 123, 19, p. 2953 - 2959 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Paraneoplastisk pancytopeni hos en patient med uerkendt lungecancer
Hansen, J. W., Sjö, L. & Grønbæk, Kirsten, 2014, In: Ugeskrift for Laeger. 176, 19, p. 2-3 2 p., V11130675.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of epigenetics in the biology of multiple myeloma
Dimopoulos, K., Gimsing, P. & Grønbæk, Kirsten, 2014, In: Blood Cancer Journal. 4, 5, p. 1-10 10 p., e207.Research output: Contribution to journal › Review › Research › peer-review
- Published
Validation of a diagnostic miRNA classifier in cutaneous T-cell lymphomas
Marstrand, T., Ahler, C. B., Ralfkiaer, U., Clemmensen, A., Kopp, K. L., Sibbesen, N. A., Krejsgaard, T., Litman, Thomas, Wasik, M. A., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Gjerdum, L. M. R., Gniadecki, R., Ralfkiaer, E., Geisler, Carsten, Woetmann, Anders , Røpke, M. A., Glue, C., Skov, Lone & Ødum, Niels, 2014, In: Leukemia and Lymphoma. 55, 4, p. 957-958 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37722667
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2553
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miR-449 inhibits cell proliferation and is down-regulated in gastric cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
417
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Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
386
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TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy
Research output: Contribution to journal › Journal article › Research
Published