Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2018
  2. Published

    Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

    Jerkeman, M., Eskelund, C. W., Hutchings, M., Räty, R., Wader, K. F., Laurell, A., Toldbod, H., Pedersen, L. B., Niemann, Carsten, Dahl, C., Kuitunen, H., Geisler, C. H., Grønbæk, Kirsten & Kolstad, A., 2018, In: The Lancet Haematology. 5, 3, p. e109-e116 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of TP53 mutations in mantle cell lymphoma

    Eskelund, C. W., Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Pedersen, L. B., Geisler, C. H., Jerkeman, M. & Grønbæk, Kirsten, 2018, In: Haematologica. 103, 11, p. e541-e543 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy

    Dahl, M., Kristensen, L. S. & Grønbæk, Kirsten, 2018, In: International Journal of Molecular Sciences. 19, 9, 26 p., 2475.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Long-term clinical outcomes of patients with hematologically unexplained cytopenia after routine assessment: A single center study

    Johansen, M. M., Andersen, M. A., Grønbæk, Kirsten & Hansen, Jakob Werner, 2018, In: European Journal of Haematology. 101, 5, p. 595–603 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mother–child transmission of epigenetic information by tunable polymorphic imprinting

    Carpenter, B. L., Zhou, W., Madaj, Z., DeWitt, A. K., Ross, J. P., Grønbæk, Kirsten, Liang, G., Clark, S. J., Molloy, P. L. & Jones, P. A., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11970-E11977 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging

    Barré, F. P. Y., Claes, B. S. R., Dewez, F., Peutz-Kootstra, C., Munch-Petersen, H. F., Grønbæk, Kirsten, Lund, Anders H., Heeren, R. M. A., Côme, Christophe Roger Michel & Cillero-Pastor, B., 2018, In: Analytical Chemistry. 90, 24, p. 14198-14206 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

    Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, Kirsten, Tost, J. & Jacobsen, Søren, 2018, In: Arthritis & rheumatology (Hoboken, N.J.). 70, 6, p. 878-890 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Mature lymphoid malignancies: origin, stem cells, and chronicity

    Husby, Simon & Grønbæk, Kirsten, Nov 2017, In: Blood advances. 1, 25, p. 2444-2455 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

    mxz703, mxz703 & Grønbæk, Kirsten, Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

    Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  13. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1–Infected Individuals and Are Associated With Markers of Systemic Inflammation

    Ballegaard, V., Ralfkiaer, U., Pedersen, K. K., Hove, M., Koplev, S., Brændstrup, P., Ryder, L. P., Madsen, H. O., Gerstoft, Jan, Grønbæk, Kirsten & Nielsen, S. D., 1 Apr 2017, In: Journal of Acquired Immune Deficiency Syndromes. 74, 4, p. e104-e113

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years

    Kolstad, A., Pedersen, L. B., Eskelund, C. W., Husby, S., Grønbæk, K., Jerkeman, M., Laurell, A., Räty, R., Elonen, E., Andersen, N. S., Brown, P. D. N., Kimby, E., Bentzen, H., Sundström, C., Ehinger, M., Karjalainen-Lindsberg, M. L., Delabie, J., Ralfkiær, E., Fagerli, U. M., Nilsson-Ehle, H. & 5 others, Lauritzsen, G. F., Kuittinen, O., Niemann, Carsten, Geisler, C. H. & the Nordic Lymphoma Group, T. N. L. G., Mar 2017, In: Biology of Blood and Marrow Transplantation. 23, 3, p. 428-435 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

    Eskelund, C. W., Dahl, C., Hansen, Jakob Werner, Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, Simon, Freiburghaus, C., Ek, S., Vestergaard, Anja Holm, Niemann, Carsten, Raty, R., Brown, Peter de Nully, Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, Kirsten, 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

    Myrtue Nielsen, H., Andersen, Christen Bertel L, Westman, M., Sommer Kristensen, L., Asmar, F., Arvid Kruse, T., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Hasselbalch, Hans Carl, Punj, V. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 6774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters

    Helbo, A. S., Lay, F. D., Jones, P. A., Liang, G. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 41947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Årsagen til uforklaret cytopeni kan ofte findes med fokuseret DNA-sekventering

    Hansen, J. W., Husby, S. & Grønbæk, Kirsten, 2017, In: Ugeskrift for Laeger. 179, 25, 4 p., V03170179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

    Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungström, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C. M., Couronné, L. & 35 others, Lenze, D., Baldus, C. D., Bastard, C., Okosun, J., Fitzgibbon, J., Dörken, B., Drexler, H. G., Roos-Weil, D., Schmitt, C. A., Munch-Petersen, H. D., Zenz, T., Hansmann, M., Strefford, J. C., Enblad, G., Bernard, O. A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Grønbæk, Kirsten, Lopez-Guillermo, A., Ogawa, S., Küppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R., Ott, G., Vassilakopoulos, T. P., Hummel, M., Rosenquist, R. & Damm, F., 8 Dec 2016, In: Blood. 128, 23, p. 2666-2670 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

    Hansen, Jakob Werner, Westman, M. K., Sjö, Lene Dissing, Saft, L., Sommer Kristensen, L., mxz703, mxz703, Treppendahl, M., Andersen, M. K. & Grønbæk, Kirsten, Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine

    Liu, M., Ohtani, H., Zhou, W., mxz703, mxz703, Charlet, J., Zhang, Y. W., Shen, H., Baylin, S. B., Liang, G., Grønbæk, Kirsten & Jones, P. A., 13 Sep 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 37, 7 p., 10238-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Immune Mechanisms in Myelodysplastic Syndrome

    Glenthøj, A., mxz703, mxz703, Hansen, Jakob Werner, Hadrup, S. R., O'Connell, C. & Grønbæk, Kirsten, 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

    Munch-Petersen, H. D., Asmar, F., Dimopoulos, K., Areškevičiūtė, A., Brown, Peter de Nully, Girkov, M. S., Pedersen, A., Sjö, Lene Dissing, Heegaard, Steffen, Broholm, H., Kristensen, L. S., Ralfkiaer, E. & Grønbæk, Kirsten, 22 Apr 2016, In: Acta Neuropathologica Communications. 4, 13 p., 40.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma

    Kristensen, L. S., Michaelsen, Signe Regner, Dyrbye, H., Aslan, D., Grunnet, K., Christensen, I. J., Poulsen, H. S., Grønbæk, Kirsten & Broholm, H., Mar 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 3, p. 246-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

    Sommer Kristensen, L., Hansen, Jakob Werner, Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, Ole Birger Vesterager, Brown, Peter de Nully & Grønbæk, Kirsten, 2016, In: Clinical Epigenetics. 8, 11 p., 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 37722667