Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2020
  2. Published

    Clonal hematopoiesis evolves from pretreatment clones and stabilizes after end of chemotherapy in patients with MCL

    Eskelund, C. W., Husby, Simon, Favero, Francesco, Klausen, T. W., Rodriguez Gonzalez, Francisco G, Kolstad, A., Pedersen, L. B., Räty, R. K., Geisler, C. H., Jerkeman, M., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2020, In: Blood. 135, 22, p. 2000-2004

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

    Hansen, Jakob Werner, Pedersen, D. A., Larsen, L. A., Husby, Simon, Clemmensen, S. B., Hjelmborg, J., Favero, Francesco, Weischenfeldt, Joachim Lütken, Christensen, K. & Grønbæk, Kirsten, 2020, In: Blood. 135, 4, p. 261-268

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

    Saini, S. K., Ørskov, A. D., Bjerregaard, A. M., Unnikrishnan, A., Holmberg-Thydén, S., Borch, A., Jensen, K. V., Anande, G., Bentzen, A. K., Marquard, A. M., Tamhane, T., Treppendahl, M. B., Gang, A. O., Dufva, I. H., Szallasi, Z., Ternette, N., Pedersen, A. G., Eklund, A. C., Pimanda, J., Grønbæk, K. & 1 others, Hadrup, S. R., 2020, In: Nature Communications. 11, 1, 5660.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes

    Wedge, E., Sengeløv, Henrik, Hansen, Jakob Werner, Andersen, N. S., Schjødt, I., Petersen, S. L., Kornblit, B., Grønbæk, Kirsten & Friis, L. S., 2020, In: Biology of Blood and Marrow Transplantation. 26, 6, p. 1091-1098

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study

    Ferrero, S., Rossi, D., Rinaldi, A., Bruscaggin, A., Spina, V., Eskelund, C. W., Evangelista, A., Moia, R., Kwee, I., Dahl, C., Di Rocco, A., Stefoni, V., Diop, F., Favini, C., Ghione, P., Mahmoud, A. M., Schipani, M., Kolstad, A., Barbero, D., Novero, D. & 13 others, Paulli, M., Zamò, A., Jerkeman, M., Gomez Da Silva, M., Santoro, A., Molinari, A., Ferreri, A., Grønbæk, Kirsten, Piccin, A., Cortelazzo, S., Bertoni, F., Ladetto, M. & Gaidano, G., 2020, In: Haematologica. 105, 6, p. 1604-1612

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The diagnostic and prognostic role of flow cytometry in idiopathic and clonal cytopenia of undetermined significance (ICUS/CCUS): A single-center analysis of 79 patients

    Dimopoulos, K., Hansen, O. K., Sjö, Lene Dissing, Saft, L., Schjødt, I. M., Hansen, Jakob Werner & Grønbæk, Kirsten, 2020, In: Cytometry. Part B: Clinical Cytometry. 98, 3, p. 250-258

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples

    Jørgensen, S., Paulsen, I. W., Hansen, Jakob Werner, Tholstrup, Dorte Maegaard, Hother, C., Sørensen, E., Petersen, M. S., Nielsen, K. R., Rostgaard, K., Larsen, M. A. H., Brown, Peter de Nully, Ralfkiær, E., Homburg, K. M., Hjalgrim, Henrik, Erikstrup, C., Ullum, H., Troelsen, J., Grønbæk, Kirsten & Pedersen, Ole Birger Vesterager, 2020, In: Scientific Reports. 10, 1, 9637.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    p53 is associated with high-risk and pinpoints TP53 missense mutations in mantle cell lymphoma

    Rodrigues, J. M., Hassan, M., Freiburghaus, C., Eskelund, C. W., Geisler, C., Räty, R., Kolstad, A., Sundström, C., Glimelius, I., Grønbæk, Kirsten, Kwiecinska, A., Porwit, A., Jerkeman, M. & Ek, S., 2020, In: British Journal of Haematology. 191, 5, p. 796-805

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2019
  12. Published

    Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology

    Nielsen, A. B., Zhou, M., de Smith, A. J., Wang, R., McCoy, L., Hansen, H., Morimoto, L., Grønbæk, Kirsten, Johansen, Christoffer, Kogan, S. C., Metayer, C., Bracci, P. M., Ma, X. & Wiemels, J. L., Nov 2019, In: Haematologica. 104, 11, p. e514-e516 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

    Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients

    Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Epigenetic therapy in hematological cancers

    Dimopoulos, K. & Grønbæk, Kirsten, 2019, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 127, 5, p. 316-328 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma

    Dimopoulos, K., Fibiger Munch-Petersen, H., Winther Eskelund, C., Sjö, Lene Dissing, Ralfkiær, E., Gimsing, P. & Grønbæk, Kirsten, 2019, In: Leukemia and Lymphoma. 60, 1, p. 180-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up

    Baliakas, P., Tesi, B., Wartiovaara-kautto, U., Stray-pedersen, A., Friis, L. S., Dybedal, I., Hovland, R., Jahnukainen, K., Raaschou-Jensen, K., Ljungman, P., Rustad, C. F., Lautrup, C. K., Kilpivaara, O., Kittang, A. O., Grønbæk, Kirsten, Cammenga, J., Hellström-lindberg, E. & Andersen, M. K., 2019, In: HemaSphere. 3, 6, p. 1-10 e321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2018
  19. Published

    Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies

    Dahl, M., Daugaard, I., Andersen, M. S., Hansen, T. B., Grønbæk, Kirsten, Kjems, J. & Kristensen, L. S., 1 Dec 2018, In: Laboratory Investigation. 98, 12, p. 1657-1669 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Vitamin C - A new player in regulation of the cancer epigenome

    Gillberg, Linn, mxz703, mxz703, Liu, M., Harsløf, L. B. S., Jones, P. A. & Grønbæk, Kirsten, Aug 2018, In: Seminars in Cancer Biology. 51, p. 59-67

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon-independent manner

    Dimopoulos, K., Søgaard Helbo, A., Fibiger Munch-Petersen, H., Sjö, Lene Dissing, Christensen, J., Sommer Kristensen, L., Asmar, F., Hermansen, N. E. U., O'Connel, C., Gimsing, P., Liang, G. & Grønbæk, Kirsten, Feb 2018, In: Molecular Oncology. 12, 2, p. 180-195

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Autoimmune Processes as an Important Parameter for the Pathogenesis of Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

    Kaastrup, K., Grønbæk, Kirsten, Hadrup, S. R. & Glenthoj, A., 2018, In: Journal of Blood & Lymph. 08, 02

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity

    Freiburghaus, C., Emruli, V. K., Johansson, A., Eskelund, C. W., Grønbæk, Kirsten, Olsson, R., Ek, F., Jerkeman, M. & Ek, S., 2018, In: BMC Cancer. 18, 1, 17 p., 466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

    Husby, S., Francesco, F., Nielsen, C., Sorensen, B., Baech, J., Hansen, J. W., Gonzalez, G. G. R., Arboe, B., Andersen, L. P., Hastrup, E. K., Fischer-Nielsen, A., Saekmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Knudsen, L. M., Grell, K., Segel, E. K., Ebbesen, L. H., Thorsgaard, M. & 6 others, Josefsson, P. L., El-Galaly, T. C., Brown, Peter de Nully, Weisenfeldt, J., Larsen, T. S. & Grønbæk, Kirsten, 2018, In: Blood. 132, Suppl 1, p. 607 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    DNA methylation levels of the ELMO gene promoter CpG islands in human glioblastomas

    Michaelsen, Signe Regner, Aslan, D., Urup, T., Poulsen, H. S., Grønbæk, Kirsten, Broholm, H. & Kristensen, L. S., 2018, In: International Journal of Molecular Sciences . 19, 3, 13 p., 679.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Epidemiology of chronic red-cell transfusion recipients in Sweden and Denmark-a 10 year follow-up study

    Didriksen, Maria, Rostgaard, K., Grønbæk, Kirsten, Pedersen, Ole Birger Vesterager, Titlestad, K., Erikstrup, C., Nielsen, K. R., Edgren, G., Ullum, H. & Hjalgrim, H., 2018, In: Vox Sanguinis. 113, 8, p. 770-778 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

    Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Human endogenous retroviruses and their implication for immunotherapeutics of cancer

    Attermann, A. S., Bjerregaard, A., Saini, S. K., Grønbæk, Kirsten & Hadrup, S. R., 2018, In: Annals of Oncology. 29, 11, p. 2183-2191 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 37722667