Anne Tybjærg-Hansen
Clinical Professor
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Molecular diagnosis of intermediate and severe alpha(1)-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals
Dahl, M., Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, Jan 2001, In: Clinical Chemistry. 47, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Late-breaking abstract: Glutathione-S-transferase P1 Ile105Val polymorphism associated with elevated lung function and reduced risk of lung cancer and death in 66,000 individuals
Dahl, Morten, Norskov, M., Nordestgaard, B. & Tybjærg-Hansen, Anne, Sep 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Cystic fibrosis ΔF508 heterozygotes, smoking, and reproduction: studies of 9141 individuals from a general population sample
Dahl, M., Tybjærg-Hansen, Anne, Wittrup, H. H., Lange, Peter & Nordestgaard, Børge, 1998, In: Genomics. 50, 1, p. 89-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion
Dahl, M., Nordestgaard, Børge, Lange, Peter & Tybjærg-Hansen, Anne, May 2001, In: Journal of Allergy and Clinical Immunology. 107, 5, p. 818-23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease
Dahl, M., Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Asthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based study
Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 2005, In: Respiratory Research. 6, p. 113Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease
Dahl, Morten, Vestbo, J., Lange, Peter, Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 1 Feb 2007, In: American Journal of Respiratory and Critical Care Medicine. 175, 3, p. 250-255Research output: Contribution to journal › Journal article › Research › peer-review
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DeltaF508 heterozygosity in cystic fibrosis and susceptibility to asthma
Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 27 Jun 1998, In: Lancet. 351, 9120, p. 1911-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A population-based study of morbidity and mortality in mannose-binding lectin deficiency
Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 17 May 2004, In: Journal of Experimental Medicine. 199, 10, p. 1391-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Change in lung function and morbidity from chronic obstructive pulmonary disease in alpha1-antitrypsin MZ heterozygotes: A longitudinal study of the general population
Dahl, M., Tybjærg-Hansen, Anne, Lange, Peter, Vestbo, J. & Nordestgaard, Børge, 19 Feb 2002, In: Annals of Internal Medicine. 136, 4, p. 270-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular diagnosis of intermediate and severe α<inf>1</inf>-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individuals
Dahl, Morten, Nordestgaard, Børge, Lange, Peter, Vestbo, J. & Tybjærg-Hansen, Anne, 2001, In: Clinical Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
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Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society
Cuchel, M., Bruckert, E., Ginsberg, H. N., Raal, F. J., Santos, R. D., Hegele, R. A., Kuivenhoven, J. A., Nordestgaard, B. G., Descamps, O. S., Steinhagen-Thiessen, E., Tybjærg-Hansen, A., Watts, G. F., Averna, M., Boileau, C., Borén, J., Catapano, A. L., Defesche, J. C., Hovingh, G. K., Humphries, S. E., Kovanen, P. T. & 11 others, , 21 Aug 2014, In: European Heart Journal. 35, 32, p. 2146-2157 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The European heart journal: Leading the fight to reduce the global burden of cardiovascular disease
Crea, F., Badimon, L., Berry, C., de Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjærg-Hansen, Anne & EHJ Editorial Board, E. E. B., 2020, In: European Heart Journal. 41, 33, p. 3113-3116 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
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The European Heart Journal: fulfilling the mission
Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C. & Tybjærg-Hansen, Anne, 2022, In: European Heart Journal. 43, 23, p. 2181-2184 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Epigenetic Regulation of F2RL3 Associates with Myocardial Infarction and Platelet Function
Corbin, L. J., White, S. J., Taylor, A. E., Williams, C. M., Taylor, K., Van Den Bosch, M. T., Teasdale, J. E., Jones, M., Bond, M., Harper, M. T., Falk, L., Groom, A., Hazell, G. G. J., Paternoster, L., Munafò, M. R., Nordestgaard, B. G., Tybjærg-Hansen, A., Bojesen, S. E., Relton, C., Min, J. L. & 4 others, , 2022, In: Circulation Research. 130, 3, p. 384-400 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Xanthelasmata, arcus corneae, and ischaemic vascular disease and death in general population: prospective cohort study
Christoffersen, M., Frikke-Schmidt, R., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: B M J. 343, p. d5497Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic risk scores: how much do they add?
Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: Current Opinion in Lipidology. 32, 3, p. 157-162 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study
Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 4 Mar 2014, In: Circulation Research. 129, 9, p. 990-998 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications
Christoffersen, M. & Tybjærg-Hansen, Anne, Jan 2016, In: Ageing Research Reviews. 25, p. 24-41 18 p.Research output: Contribution to journal › Review › Research › peer-review
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Targeting IL-6 in patients at high cardiovascular risk
Christoffersen, M. & Tybjærg-Hansen, Anne, 2021, In: The Lancet. 397, 10289, p. 2025-2027 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Novel genes in LDL metabolism: a comprehensive overview
Christoffersen, M. & Tybjærg-Hansen, Anne, Jun 2015, In: Current Opinion in Lipidology. 26, 3, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic Risk Scores
Christoffersen, M. & Tybjærg-Hansen, Anne, 2022, Cardiovascular Risk Assessment in Primary Prevention. Humana Press, p. 429-446 (Contemporary Cardiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses
Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Mar 2017, In: Experimental Gerontology. 89, p. 69-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Xanthelasmas Predict Risk of Ischemic Heart Disease, Myocardial Infarction, and Overall Death in the General Population
Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 33 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles
Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.Research output: Contribution to journal › Journal article › Research › peer-review
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The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles
Christoffersen, C., Benn, M., Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Dahlbäck, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research. 53, 10, p. 2198-204 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2
Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.Research output: Contribution to journal › Journal article › Research › peer-review
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Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?
Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S., Svendsen, Jesper Hastrup, Christensen, A. H., Benn, M., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 2, p. 148-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening of Three Novel Candidate Genes in Arrhythmogenic Right Ventricular Cardiomyopathy
Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Genetic Testing and Molecular Biomarkers. 15, 4, p. 267-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population
Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients - disease - causing or innocent bystanders?
Christensen, A. H., Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, J. H., 2009, In: Cardiology. 115, 2, p. 148-154 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy
Christensen, Alex Hørby, Andersen, C. B., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Clinical Genetics. 80, 3, p. 256-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Wide spectrum of desmosomal mutations in Danish patients with arrhythmogenic right ventricular cardiomyopathy
Christensen, A. H., Benn, M., Bundgaard, H., Tybjærg-Hansen, Anne, Haunsø, Stig & Svendsen, Jesper Hastrup, Nov 2010, In: Journal of Medical Genetics. 47, 11, p. 736-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
Chapman, M. J., Ginsberg, H. N., Amarenco, P., Andreotti, F., Borén, J., Catapano, A. L., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Nordestgaard, Børge, Ray, K. K., Reiner, Z., Taskinen, M., Tokgözoglu, L., Tybjærg-Hansen, Anne, Watts, G. F. & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 2011, In: European Heart Journal (English Edition). 32, 11, p. 1345-61 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study
Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.Research output: Contribution to journal › Journal article › Research › peer-review
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Surfactant protein-B 121ins2 heterozygosity, reduced pulmonary function, and chronic obstructive pulmonary disease in smokers
Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Jan 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Surfactant Protein-B 121ins2 Heterozygosity, Reduced Pulmonary Function and COPD in Smokers
Bækvad-Hansen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2010, In: American Journal of Respiratory and Critical Care Medicine. 181, 1, p. 17-20 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables
Burgess, S., Thompson, S. G., Thompson, G., Andrews, G., Samani, N. J., Hall-Andersen, A. M., Whincup, P., Morris, R., Lawlor, D. A., Davey Smith, G., Timpson, N., Ebrahim, S., Ben-Shlomo, Y., Brown, M., Ricketts, S., Sandhu, M., Reiner, A., Psaty, B., Lange, L., Cushman, M. & 31 others, , 30 May 2010, In: Statistics in Medicine. 29, 12, p. 1298-311 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomet i kardiologien
Bundgård, Henning, Diness, Birgitte Rode, Tfelt-Hansen, Jacob, Henriksen, F. L., Eschen, O., Skovby, F., Havndrup, O., Jensen, H. K. & Tybjærg-Hansen, Anne, 2014, In: Ugeskrift for Laeger. 176, 46, 5 p., V06140376.Research output: Contribution to journal › Journal article › Research › peer-review
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25-hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants
Brøndum-Jacobsen, P., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: Journal of Thrombosis and Haemostasis. 11, 3, p. 423-431Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in SUSD2 are associated with the risk of ischemic heart disease
Bruikman, C. S., Dalila, N., van Capelleveen, J. C., Kroon, J., Peter, J., Havik, S. R., Willems, M., Huisman, L. C., de Boer, O. J., Hovingh, G. K., Tybjærg-Hansen, Anne & Dallinga-Thie, G. M., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 470-481Research output: Contribution to journal › Journal article › Research › peer-review
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Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M. & 31 others, , 2011, In: American Journal of Human Genetics. 89, 5, p. 619-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Zeller, T., Liquet, B., Newcombe, P., Yengo, L., Wild, P. S., Schillert, A., Ziegler, A., Nielsen, S. F., Butterworth, A. S., Ho, W. K., Castagné, R., Munzel, T., Tregouet, D., Falchi, M., Cambien, F., Nordestgaard, B., Fumeron, F. & 7 others, , 2013, In: P L o S Genetics. 9, 8, p. 1-17 17 p., e1003657.Research output: Contribution to journal › Journal article › Research › peer-review
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Common genetic variation in mc4r does not affect atherosclerotic plaque phenotypes and cardiovascular disease outcomes
Blauw, L. L., Noordam, R., van der Laan, S. W., Trompet, S., Kooijman, S., van Heemst, D., Jukema, J. W., van Setten, J., de Borst, G. J., Tybjærg-Hansen, Anne, Pasterkamp, G., Berbée, J. F. P. & Rensen, P. C. N., 2021, In: Journal of Clinical Medicine. 10, 5, 12 p., 932.Research output: Contribution to journal › Journal article › Research › peer-review
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Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010
Bernini, F., Fisher, R., Freeman, D., Groen, A., Kalopissis, A., Malle, E., Mulder, M., Niemeier, A., Parini, P., Tybjærg-Hansen, Anne & von Eckardstein, A., 2011, In: Atherosclerosis. 215, 1, p. 249-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011
Bernini, F., Costet, P., Ehrenborg, E., Fisher, R., Fielding, B., Freeman, D., Groen, A., Malle, E., Mulder, M., Niemeier, A., Tybjærg-Hansen, Anne & von Eckardstein, A., 2012, In: Atherosclerosis. 221, p. 287-93Research output: Contribution to journal › Journal article › Research
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European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008
Bernini, F., Freeman, D., Groen, A., Heeren, J., Kalopissis, A., Kronenberg, F., Lindstedt, K., Parini, P., Schuster, G., Tybjærg-Hansen, Anne, Dij, K. W. V. & Eckardstein, A. V., 2009, In: Atherosclerosis. 205, 1, p. 41-47 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
Research output: Contribution to journal › Journal article › Research › peer-review
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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